FR2596159B1 - APPARATUS AND METHOD FOR DETERMINING POLYNUCLEOTIDES - Google Patents

APPARATUS AND METHOD FOR DETERMINING POLYNUCLEOTIDES

Info

Publication number
FR2596159B1
FR2596159B1 FR8703886A FR8703886A FR2596159B1 FR 2596159 B1 FR2596159 B1 FR 2596159B1 FR 8703886 A FR8703886 A FR 8703886A FR 8703886 A FR8703886 A FR 8703886A FR 2596159 B1 FR2596159 B1 FR 2596159B1
Authority
FR
France
Prior art keywords
polynucleotides
determining
determining polynucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8703886A
Other languages
French (fr)
Other versions
FR2596159A1 (en
Inventor
B. Hirschfeld Tomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2596159A1 publication Critical patent/FR2596159A1/en
Application granted granted Critical
Publication of FR2596159B1 publication Critical patent/FR2596159B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
FR8703886A 1986-03-21 1987-03-20 APPARATUS AND METHOD FOR DETERMINING POLYNUCLEOTIDES Expired - Lifetime FR2596159B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84214686A 1986-03-21 1986-03-21

Publications (2)

Publication Number Publication Date
FR2596159A1 FR2596159A1 (en) 1987-09-25
FR2596159B1 true FR2596159B1 (en) 1994-01-07

Family

ID=25286639

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8703886A Expired - Lifetime FR2596159B1 (en) 1986-03-21 1987-03-20 APPARATUS AND METHOD FOR DETERMINING POLYNUCLEOTIDES

Country Status (5)

Country Link
JP (1) JP2735189B2 (en)
CA (1) CA1299074C (en)
DE (1) DE3708513C2 (en)
FR (1) FR2596159B1 (en)
GB (1) GB2190189B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937198A (en) * 1989-07-28 1990-06-26 Becton, Dickinson And Company Novel fluorescent dye
DE69125441T2 (en) * 1990-09-28 1997-11-06 Toshiba Kawasaki Kk Gene detection method
US5776672A (en) * 1990-09-28 1998-07-07 Kabushiki Kaisha Toshiba Gene detection method
WO1993020240A1 (en) * 1992-04-06 1993-10-14 Abbott Laboratories Method and device for detection of nucleic acid or analyte using total internal reflectance
DE19518217A1 (en) * 1994-05-11 1995-11-30 Imtec Immundiagnostika Gmbh Determn of DNA after capture by probe immobilised on solid phase
EP0795032A2 (en) * 1994-12-22 1997-09-17 Abbott Laboratories Methods of immobilizing oligonucleotides to solid support materials and methods of using support bound oligonucleotides
DE10118465A1 (en) * 2001-04-07 2002-10-10 Zeiss Carl Jena Gmbh Optical component holding unit, consists of a material with a smaller refractive index than that of the optical component

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1180647A (en) * 1981-07-17 1985-01-08 Cavit Akin Light-emitting polynucleotide hybridization diagnostic method
US4447546A (en) * 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube
GB8311905D0 (en) * 1983-04-29 1983-06-02 Cox R A Isolation and detection of nucleotide sequence
US4737454A (en) * 1983-07-14 1988-04-12 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US4724202A (en) * 1983-12-12 1988-02-09 Molecular Diagnostics, Inc. Use of non-hybridizable nucleic acids for the detection of nucleic acid hybridization
US4671938A (en) * 1985-09-09 1987-06-09 Ciba-Corning Diagnostics, Corp. Immunoassay apparatus
EP0245206A1 (en) * 1986-05-05 1987-11-11 IntraCel Corporation Analytical method for detecting and measuring specifically sequenced nucleic acid

Also Published As

Publication number Publication date
DE3708513C2 (en) 1998-11-05
JPS62266464A (en) 1987-11-19
JP2735189B2 (en) 1998-04-02
FR2596159A1 (en) 1987-09-25
CA1299074C (en) 1992-04-21
GB2190189B (en) 1990-06-13
GB2190189A (en) 1987-11-11
DE3708513A1 (en) 1987-09-24
GB8705957D0 (en) 1987-04-15

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