FR2588723A1 - ANTI-DEGLUTITION SOLID HERBICIDE COMPOSITION CONTAINING PARAQUAT AND THICKENING AGENT - Google Patents

Abstract

IT INCLUDES A 1,1-DIMETHYL-4,4-DIPYRIDYLIUM SALT AND A THICKENER, A WATER-ABSORBING FINE MINERAL POWDER, CAPABLE OF CONVERTING A WATER-BASED SOLUTION OF 1-1-DIMETHYL-4,4-DIPYRIDYLIUM INTO A FORM SOLID. THE WATER-ABSORBING FINE MINERAL POWDER IS CONSTITUTED BY AT LEAST ONE GROUP MEMBER FORMED BY WHITE CARBON, DIATOMATED EARTH, FINALLY DIVIDED CALCIUM SILICATE, PERLITE, CALCINE CAOLIN, AND ZEOLITE. THE THICKENING AGENT IS AT LEAST ONE AGENT OF THE GROUP CONSTITUTED BY THE SALTS OF ALGINIC ACID, PROPYLENE GLYCOL ALGINATES, CARRAGEENAN, GUAR GUM, MODIFIED GUAR GUM, XANTHAN GUM, XANTHAN GUM, MODIFIED SANDS CARBOXYMETHYL CELLULOSE, METHYL CELLULOSE, HYDROXYALKYL CELLULOSES, PECTIN, LOCUST BEAN GUM, CARBOXYMETHYL SALTS STARCH, PULLULANE, POLYVINYL ALCOYLRYL AMERICAN AND POLYRACYL ACRYLID AMBER, POLYRACINYL ACRYLRYLRYLIDE AND POLYRACIDRIS AMERRY . APPLICATION TO THE PREVENTION OF INTOXICATIONS.

Description

SOLID HERBICIDE COMPOSITION

ANTI - DEGLUTITION

  The invention relates to a solid anti-swallowing herbicide composition (i.e., a herbicidal composition which does not readily swallow). More particularly, it relates to a solid anti-swallowing herbicide composition containing, as a herbicidal agent, a salt of 1,1'-4,4'-dimethyl-pyridylium (called "paraquat"), which is not easily swallowed, even if such

  Paraquat solution was drunk accidentally or intentionally.

  The importance of herbicides or pesticides in agriculture is widely recognized, and many herbicides or pesticides are used in practice. Herbicides or pesticides used in practice should be deposited and registered, after having undergone a severe examination including toxicity and safety, in accordance with current laws and regulations. As a result, as long as herbicides or pesticides are used properly, following the instructions for use, they are not dangerous to the human body in any way. However, in the current state of affairs, poisoning accidents caused by a portion of herbicide or pesticide still occur, despite the fact that the correct handling of herbicides or pesticides and the prevention thus exercised against the possible risks incurred by the human body, have been studied and that the dangers of misuse have been widely disseminated for a long time. In particular a herbicide,

  paraquat is widespread because of its high herbicidal activity.

  and its ease of application, and quite a few

  poisoning accidents were caused by accidental ingestion

  such or intentional paraquat, despite clear indications as to its toxicity. The reason is that paraquat is

  characterized by very high acute toxicity and is available

  commercially available in the form of an aqueous concentrate solution

relatively high.

  Paraquat is generally marketed as an approximately 20 to 30% aqueous solution. For use, the crude paraquat solution is diluted 300 to 1500 times with water and the resulting dilute paraquat solution is generally sprayed as a herbicide at a rate of 100 to 150 liters per 100 m. The acute oral toxicity of paraquat is an LD50 of 166 to 217 mg / kg (rat) and is described in "Kyukyu Igaku" 4 (4), p. 399 (1980), that the lethal dose of paraquat for humans is about 15 ml of a 20% aqueous solution. On the other hand, he

  is described in "Gekkan Yakuji" 25 (8), p. 147 (1983), that a quantity

  The average amount swallowed in one sip by an adult is about 1 ml in general. This means that, if a commercial paraquat solution is accidentally or intentionally ingested, a sip of the paraquat solution is enough to be lethal

for a human being.

  Various attempts have been made to prevent

  accidental damage caused by paraquat. For example, odorant or coloring compositions are incorporated into the paraquat solutions to prevent accidental ingestion by imparting an unpleasant odor or color. However, this is ineffective - in the case of children or against voluntary ingestion. In addition, it has been proposed to include in paraquat solutions nausea or emetic, in order to quickly remove from the stomach and digestive system paraquat ingested inadvertently before the paraquat is absorbed by the body. However, it is unfortunate to note that currently, once paraquat has been swallowed, there is no effective method of treatment although it depends on the amount swallowed, even though paraquat has been

vomited at an early stage.

  Accordingly, although various attempts have been made to solve the above-mentioned problems, an appropriate and effective means has not been found so far. In order to prevent accidental poisoning caused by oral ingestion of paraquat, the concentration of paraquat marketed is expected to be reduced so that a lethal amount is not reached if a relatively large amount of paraquat has not been swallowed. However, this causes disadvantages in the transport and storage of paraquat solutions and also adversely affects the handling of paraquat. On the other hand, it is considered that when paraquat is marketed in solid form, in place of an aqueous solution, paraquat is hardly ingested, poisoning caused by accidental ingestion of paraquat can be prevented and plus, its transportation and storage are more convenient. However, since paraquat is completely soluble in water, it is easy to prepare an aqueous solution containing a lethal amount of paraquat, from this solid paraquat with a sip of water, and it would be difficult to prevent ingestion

  poison with suicidal intent.

  Accordingly, the object of the present invention is to eliminate the aforementioned disadvantages of paraquat and to provide a solid anti-swallowing herbicide composition for the effective prevention of acute intoxication caused by accidental or deliberate ingestion of paraquat, without adversely affect its essential characteristics, to

  know, a strong herbicidal action and easy application.

  Other objects and advantages of the present invention

  will appear in the light of the description below.

  In accordance with the present invention, there is provided a solid herbicide anti-swallowing composition, comprising a salt

  1,1'-dimethyl-4,4'-bipyridylium and a thickening agent.

  According to the invention, since the herbicidal composition

  It is in solid form and contains a thickening agent, it is difficult to swallow in the solid form, and if a quantity of the composition corresponding to a lethal dose for a human being is dissolved in a glass of water, it is not obtained a non-fluidizable mixture, which is difficult to swallow. Of course, the present solid herbicidal composition can be converted into an aqueous solution by diluting the composition with a large amount of water. However, since the paraquat concentration of this diluted solution is very low, a lethal amount can not be ingested without the absorption of a very large amount of the diluted solution. This is difficult to achieve in practice and the action of nausea can be used to reduce the likelihood of death due to such ingestion. Moreover, since the present solid herbicidal composition can be stored and transported in glass or plastic containers and the present solid herbicidal composition can be used at the site by dilution with water, there is no need for essential difference between the present herbicidal solid composition and conventional commercially available paraquat solutions from the point of view of transport, handling and applicability. When the present solid herbicidal composition is diluted with a significant amount of water for use at the site, the solid herbicidal composition

  becomes a low viscosity solution suitable for spraying

  tion. In addition, the herbicidal solid composition according to the invention may optionally contain, in addition to paraquat and thickening agent, various conventional ingredients such as dyes, odor compositions and nausea, in order to perfect

  still the security of use. In addition, it is also possible

  to include surfactants and other components having herbicidal activity in the present herbicidal composition, in order to improve the herbicidal action and the ease of application of

the composition.

  The paraquat that can be used in the present herbicidal composition

  This acid is preferably in solid form. As a result, salts

  1,1'-dimethyl-4,4'-bipyridylium (e.g. dichloride, dibro-

  mure and bismethylsulfate or complex salts with for example manganese, iron, urea, thiourea, p-animophenol, catechol) in the form of crystals, can be directly mixed with the thickening agent. However, the paraquat solutions available in industry or commerce may also be used in the preparation of the present solid herbicidal composition by the addition of a mineral fine water-absorbing powder.

  to form a fluidizable solid paraquat apparently free of water.

  Any fine mineral water-absorbing powder may be used for

  this effect provided that it does not affect the herbicide action of

  - 5 - cuat and. the characteristics of the thickeners. Examples of water-absorbing fine inorganic powder are white carbon, diatomaceous earth, finely divided calcium silicate, perlite, calcined caolin and zeolite. These pouares can be used alone or in mixture. There is no critical limit to the amount of mineral fine powder absorbing water, as long as the paraquat solution can be solidified. For example, in the case of white carbon, the powder can be mixed in an identical amount, up to 10 times the amount

  of water contained in the aqueous solution of paraquat.

  There is no critical limit to the paraquat concentration of the present solid herbicidal compositions. However, I / e the paraquat concentration is too low, it is not

  necessary to use a small dilution ratio of the

  With the addition of water to obtain the desired concentration for on-site spraying, the spraying tends to become difficult from the point of view of viscosity as well as from the point of view of viscosity. transport and storage

  also tend to decrease. On the other hand, when the concentration

  Paraquat 2D of the herbicidal composition is too high, the problems mentioned above do not appear, but the authorized safety range tends to be reduced from the point of view of

  prevention of accidental poisoning.

  For these reasons, the preferred concentration range in the practice of the present paraquat herbicidal compositions is

  Between about 5% to 40% by weight.

  Thickening agents useful in the present invention are those capable of increasing the viscosity or forming the gel by adding a relatively small amount (e.g., 300 ml or less) of water to the solid herbicidal composition.

  room temperature in a short time. The types of thick agents

  are not limited to the extent that the above conditions are met. Various natural and synthetic thickeners can be used in the present invention. Typical examples of such thickeners are the salts of alginic acid, alginates of propylene glycol; - 6 - carrageenan, guar gum, modified guar gum, gum

  xanthan, modified xanthan gum, carboxymethyl

  cellulose, methyl cellulose, hydroxyalkyl celluloses,

  pectin, locust bean gum, carboxymethyl

  starch, pullulan, polyvinyl alcohol, polyvinyl

  rolidone, salts of polyacrylic acid, and polyacrylamide.

  These thickeners can be used alone or in mixture.

  In addition, various conventional acids or salts may also be used in the herbicidal compositions of the invention to further enhance the gelling or thickening characteristics of the herbicidal solid composition. The addition of mineral salts to the present herbicidal composition can further improve the gelling properties of the compositions

herbicides according to the invention.

  There are no defined concentrations of thickening agents

  in the solid herbicidal compositions present since the concentration depends to a large extent on the type of the thickening agent and the paraquat concentration. As a practical measure, the thickening agent can be used in a proportion such that the herbicidal compositions cause gelation at a paraquat concentration of 5% by weight or more when the herbicidal composition according to the invention is diluted with water. This means that when the paraquat concentration of the solid herbicide is 5 to 40% by weight, the thickening agent can be added in such a proportion that the whole composition becomes a viscous liquid or a gel that can not be swallowed easily. when the herbicidal compositions are diluted, with an equal amount of water in the case of a paraquat concentration of 5%, to 10 times the amount of water in the case of a paraquat concentration

40%.

  The solid herbicidal composition according to the invention can

  additionally, as an optional component, dyes

  odorant, nausea, and other conventional formulations to improve the safety of paraquat herbicide, as well as surfactants and other herbicidal components to improve herbicidal activity. However, it should be noted that these optional components must be added in such a proportion that the herbicidal action and other characteristics of this

  composition are not affected.

EXAMPLES

  The invention will be better understood using the examples and tests below, without being in any way limited. In the

  examples, "parts" and "%" are always by weight, unless otherwise indicated

contrary.

Examples 1 to 7

  Wettable paraquat powders were prepared by homogenous mixing and milling of solid paraquat components and other ingredients in the following formulation ratios: (1) Paraquat dichloride 25 parts Carboxymethyl sodium starch 75 parts R (PRIMOJEL: Matsutani Kagaku Kogyo Co., Ltd.) (2) Paraquat dichloride Guar gum R (EMCO GUM CSA 200/50: Meyhall - Chemical parts parts AG) Borax 20 White carbon 20 R (CARPLEX # 80: Shionogi & Co., Ltd., in "white carbon" suite) (3) paraquat dichloride Pullulan 60 R (PULLULAN PF 30: Hayashibara Seibutsukagaku Kenkyusho KK) parts parts parts white carbon 20 parts surfactant (polyoxyethylene nonylphenyl ether) parts (4) paraquat dichloride 15 parts Polyvinyl pyrrolidone 60 parts Polyvinyl pyrrolidone-K-90: White carbon Wako Pure Chemical Industries, Ltd.) Surfactant 5 parts (Polyoxyethylene ether of higher aliphatic alcohol) (5) Dichloride Paraquat 15 parts Starch 60 parts R (Solvitose C-5: Matsutaji Kagaki Kogyo Co., Ltd.) White carbon 20 parts Surfactant 5 parts (Polyoxyethylene alkylamine) (6) Paraquat dichloride 25 parts Xanthan gum 20 parts R (KELZAN : Kelco Merck Division, "Xantham Gum" below) White Carbon 30 parts Surfactant 5 parts (Polyoxyethylene nonylphenyl ether) Foaming agent malic acid 10 parts Sodium bicarbonate 10 parts (7) Paraquat dimethylsulfate 30 parts Xanthan gum 40 parts White carbon 25 parts Surfactant 5 parts (polyoxyethylene nonylphenyl ether) Examples 8 to 21 Wettable paraquat powders were prepared by homogeneous mixing and grinding of a concentrated paraquat solution (i.e., an aqueous solution containing 37% by weight of paraquat dichloride) and other ingredients of the following formulation ratios: ns-9- (8) Solution. paraquat concentrate Sodium Alginate (KELGIN R: Kelco Merck Division) White Carbon Surfactant (Polyoxyethylene Nonylphenyl Ether) (9) Concentrated Paraquat Solution Propylene Glycol Alginate (KIMIROID: Kimitsu Kagaku Kogyo KK) White Carbon Surfactant (Polyoxyethylene Nonylphenyl Ether) ) (10) Concentrated Paraquat Carrageenan Solution

(TAKARAGEN G50

(TAKARAGEN G50

  : Takagen Corporation) White Carbon Surfactant (Polyoxyethylene Nonylphenyl Ether) (11) Concentrated Paraquat Solution Guar Gum

(EMCO GUM R CSA 200/50)

  White carbon Surfactant (Polyoxyethylene nonylphenyl ether) Nausea (Hydrochloride emetine) Odor composition (e-Phenethyl alcohol) (12) Concentrated paraquat solution Modified guar gum (JAGUAR HP-8: Meyhall Chemical AG) (JAGUAR HP-B Meyhall Chemical AG ) 27 parts parts 23 parts parts parts parts 27 parts parts 23 parts parts parts parts 1 part 4 parts parts

- 10 -

  White Carbon Surfactant (Polyoxyethylene Nonylphenyl Ether) Nausea (Emitted Tartar) e-Phenethyl Alcohol (13) Concentrated Paraquat Solution Gum x: Anthane

(Kelzan)

  White Carbon Surfactant (Polyoxyethylene Nonylphenyl Ether) Anhydrous Sodium Sulfate (14) Concentrated Paraquat Solution Carboxymethyl Sodium Cellulose

(SUNROSE SN 2OTC: Sanyo

  Kokusaku Pulp Co., Ltd.) White Carbon Surfactant (Polyoxyethylene Nonylphenyl Ether) (15) Concentrated Paraquat Methyl Cellulose Solution R (MAPOROSE M-10O00: Matsumoto Yushi Seiyaku KK) White Carbon Surfactant (Polyoxyethylene Nonylphenyl Ether) (16) Concentrated Solution of paraquat carboxymethyl sodium starch

(PRIMOJEL R

  Carbon white Surfactant (Polyoxyethylene nonylphenyl ether) parts parts 1 part 4 parts parts parts parts parts 27 parts parts 23 parts 4 parts parts 36 parts 4 parts parts 57 parts 18 parts parts

- 11 -

  (17) Concentrated solution of paraquat Polyvinyl alcohol (PVA 117S: Kuraray Co., Ltd.) White carbon Surfactant (Polyoxyethylene nonylphenyl ether) (18) Concentrated paraquat solution Polyacrylamide (VISCOMATE R NS: Showa - Denko KK) White carbon Surfactant (Polyoxyethylene nonylphenyl ether) (19) Concentrated paraquat solution 27 parts parts 23 parts parts 24 parts 31 parts parts Pectin 45 parts (GENU PECTIN BB RAPID SET, Copenhagen Pectin Factory Ltd.) White carbon 23 parts Surfactant 5 parts (Polyoxyethylene nonylphenyl ether) (20) concentrated solution of paraquat A n = xanthan gum

(Kelzan)

  Locust bean gum (MEYPRODYN: Meyhall Chemical AG) (MEYPRODYN: Meyhall Chemical AG) 14 parts parts White carbon 31 parts Surfactant 5 parts (Polyoxyethylene nonylphenyl ether) (21) Concentrated paraquat solution 40 parts Xanthan gum 18 parts

(Kelzan)

  Diatomaceous earth 37 parts (RADIOLITE: Showa Kagaku K.K.) Surfactant 5 parts (Polyoxyethylene nonylphenyl ether) 9 7 nri

- 12 -

Example 22

  The following ingredients were dissolved in water Paraquat dichloride 30 parts Guar gum 30 parts R

(EMCO GUM CSA 200/50)

White carbon 23 parts R

(CARPLEX P 80)

  Surfactant 7 parts (Polyoxyethylene nonylphenyl ether) Sodium sulfate 10 parts The resulting solution was granulated by means of a

  atomizer to obtain a granulated powder of wettable paraquat.

  Examples 23 to 25 Wettable paraquat powders having the following compositions were prepared by uniform mixing and milling of a

  concentrated aqueous solution of paraquat and other ingredients.

  (23) paraquat dichloride 35 parts guar gum 23 parts

(EMCO GUM R CSA 200/50)

  White carbon 42 parts (24) Paraquat dichloride 35 parts Carrageenan 23 parts (TAKARAGEN: Takagen Corporation) White carbon. 42 parts (25) paraquat dichloride 35 parts xanthan gum 23 parts

(Kelzan)

  White Carbon 42 parts Test Example 1 30 g of a solid composition prepared in Example 1 were mixed with 150 ml of water, with stirring, so that

  obtain a mixture having a paraquat concentration of 5%.

  The mixture became pasty quickly after the addition of water.

  Thus a pasty mixture, difficult to swallow, was obtained.

  The resulting paraquat paste composition was then diluted with water to a proportion such that 50 g of the component

- 13 -

  active ingredients were included in the diluted composition. The diluted herbicidal composition thus obtained was pulverized under pressure on the foliage (or stems and leaves) of digitaria,

  cyperus, common white anserine, anserine, millet

  yard, grown in test pots, using a pressure atomizer, in a proportion such that 50 g of the active component are applied over 100 m. Before spraying, a

  conventional non-ionic spraying agent has been added to the

herbicide.

  During spraying, it did not happen

  obstruction of the spray nozzle of the atomizer.

  When the herbicidal action has been compared to that of a solution

  commercially available paraquat, 5 days after treatment.

  no significant difference could be observed.

  Test Example 2 g of a solid composition prepared in Example 11 were mixed with 150 ml of water, with stirring, in such a way as to

  obtain a mixture having a paraquat concentration of 5%.

  The mixture became pasty quickly after the addition of water.

  Thus a pasty mixture difficult to swallow was obtained.

  The resulting paraquat paste composition was then diluted with water to such an extent that 50 g of the active component was included in 150 liters of the diluted composition. The diluted herbicidal composition thus obtained was pulverized under pressure on the foliage of digitaria, cyperus, common white anserine, anserine, millet of barnyard, grown in pots

  test, using a pressure atomizer, in a proportion

  such that 50 g of the active component are spread over 100 m.

  Before spraying, a conventional non-ionic spreading agent

  has been added to the herbicide composition.

  During spraying, no obstruction of the spray nozzle of the atomizer was observed. When the herbicide actions were compared to those of a commercially available paraquat solution, 5 days after treatment, it was not

  no essential difference was observed.

- 14 -

  Test Example 3 g of a solid composition prepared in Example 13 were mixed with 150 ml of water, with stirring, so as to obtain a mixture having a paraquat concentration of 5%. The mixture became pasty shortly after the addition of water.

  Thus, a pasty mixture difficult to swallow was obtained.

  The resulting paraquat paste composition was then diluted with water to such an extent that 50 g of the active component was included in 150 liters of the diluted composition. The diluted herbicidal composition thus obtained was pulverized under pressure on the foliage of digitaria, cyperus, common white anserin, anserine, millet of backyard, grown in test pots, using a pressure atomizer, in a proportion of 50 g of active component per 100 m. Before spraying, a non-ionic spreading agent

  Conventional has been added to the herbicidal composition.

  During spraying, it did not happen

  obstruction of the spray nozzle of the atomizer.

  When the herbicide or weed control effect has been compared to that of a commercially available paraquat solution, 5 days

  after treatment, there was no significant difference between

  tial. Test Example 4 g of the composition prepared in Example 15 were mixed with 150 ml of water, with stirring, in such a way that

  obtain a mixture having a paraquat concentration of 5%.

  The mixture became pasty shortly after the addition of water.

  Thus a pasty mixture, difficult to swallow, was obtained.

  The resulting paraquat paste composition was diluted with water in a proportion such that 50 g of the component

  active ingredients are included in 150 liters of the diluted composition.

  The diluted herbicidal composition thus obtained was sprayed under pressure onto the foliage of digitaria, cyperus, common white worm, anserine, backyard millet, grown in test pots, using a pressure atomizer, in a proportion of 50 g of active component per 100 m. Before a proportion of 50 g of active component per 100 m. Before the

- 15 -

  spraying, a conventional non-ionic spreading agent has

  has been added to the herbicidal composition.

  During spraying, it did not happen

  obstruction of the spray nozzle of the atomizer.

  When the herbicide action was compared to that of a commercially available paraquat solution, 5 days

  after the treatment, there was no noticeable difference.

  Test Example 5 The herbicidal action of the paraquat wettable powders obtained in Examples 23 to 25 was evaluated in a culture field. As reference examples, an aqueous solution of paraquat at 24% and a liquid agent of bialaphos at 32% were used. The weeds used for the trial were 25 to 30 cm digitaria, 25 cm tall, yellow prickly

  height of 50 cm, and anserine having a height of 25 cm.

  The area of each test was 1.5m x 2m (ie

  ie 3 m). Samples of the diluted herbicidal composition containing 0.3% of a surfactant were sprayed using a pressurized atomizer, in a proportion of active component of 0.5 or 1 kg of A.I. (i.e., active ingredient) per ml.

  hectare and in a proportion of spray water of 1000 l / ha.

  Six days after spraying, the herbicide action was observed according to the following standards: 0 ... no action

100 ... complete destruction.

  The results are shown in Table 1. As is clear from the results shown in Table 1, since the height of the grass at the time of treatment was relatively large, complete destruction was not obtained for 0, 5 kg AI per hectare. However, for 1 kg of A.I / ha, good results were obtained and there was no essential difference between the compositions of the examples.

  and 25 and the conventional paraquat composition.

Table 1

  Composition Sample No. Rate of Application (kg ai / ha) Control of Digitaria Herbicide Activity

Example No. 23

Example NO. 24

Example No. 25

  Paraquat Bialaphos Control (no treatment) 0.5 1.0 0.5 1, o 0.5 1.0 0.5 1, 0 0.5 1, oo Persicaria o White Anserine o0 Anserine i on IO Co Co ru IU

17 2588723

Claims (8)

  1. A solid anti-swallowing herbicide composition comprising a salt of 1,1'-dimethyl-4,4'-bipyridylium in solid form and a thickening agent.   The composition of claim 1, further comprising a water-absorbing mineral fine powder capable of converting an aqueous solution of 1,1'-dimethyl-4,4'-bipyridylium to a solid form. 3. Composition according to claim 2, characterized in that the mineral fine powder absorbing water is constituted by at least one member of the group formed by white carbon, diatomaceous earth, finely divided calcium silicate, perlite, the calcined caolin, and zeolite.   4. Composition according to claim 1, characterized in that the thickening agent is at least one of the group consisting of salts of alginic acid, propylene glycol alginates, carrageenan, gomm9guar, modified guar gum, xanthan gum, modified xanthan gum, salts of carboxymethyl cellulose, methyl cellulose, hydroxyalkyl celluloses, pectin, goe, locust bean, carboxymethyl starch salts, pullulan, polyvinyl alcohol, polyvinyl pyrrolidone, the salts of polyacrylic acid, and the polyacryl amide.   5. Composition according to claim 1, characterized in that the salt content of 1,1'-diRethyl -4,4'-bipyridylium of the   composition is 5 to 40% by weight.   6. Composition according to claim 1, characterized in that the thickening agent content of the composition is such that the composition becomes practically non-viscous by adding a quantity of water equivalent to 10 times greater, calculated on the composition, and that the composition becomes a liquid to 18 2588723   low viscosity, easy to spray, by addition of at least   1500 times the amount of water calculated on the composition.   7. Composition according to claim 1, characterized in that   it further comprises a surfactant and a nausea.   8. Composition according to claim 5, characterized in that the thickener content in the composition is such that the entire composition becomes a viscous liquid or a gel that can not be swallowed easily when the herbicidal composition is diluted with an equal amount in the case of a paraquat concentration of 5%. to 10 times the amount of water in   the case of a paraquat concentration of 40%.