FR2580638B1 - NOVEL 4-PHENYLPROPYL INDOLE DERIVATIVES, SALTS THEREOF, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM - Google Patents

NOVEL 4-PHENYLPROPYL INDOLE DERIVATIVES, SALTS THEREOF, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM

Info

Publication number
FR2580638B1
FR2580638B1 FR8506135A FR8506135A FR2580638B1 FR 2580638 B1 FR2580638 B1 FR 2580638B1 FR 8506135 A FR8506135 A FR 8506135A FR 8506135 A FR8506135 A FR 8506135A FR 2580638 B1 FR2580638 B1 FR 2580638B1
Authority
FR
France
Prior art keywords
medicaments
salts
novel
preparation
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8506135A
Other languages
French (fr)
Other versions
FR2580638A1 (en
Inventor
Francois Clemence
Jacques Guillaume
Gilles Hamon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR8506135A priority Critical patent/FR2580638B1/en
Priority to US06/853,030 priority patent/US4853408A/en
Priority to ZA862974A priority patent/ZA862974B/en
Priority to AU56492/86A priority patent/AU592985B2/en
Priority to CA000507303A priority patent/CA1265805A/en
Priority to IE106386A priority patent/IE59151B1/en
Priority to DK183886A priority patent/DK167394B1/en
Priority to FI861681A priority patent/FI85138C/en
Priority to JP61092469A priority patent/JPS61249959A/en
Priority to HU861694A priority patent/HU195482B/en
Priority to EP86400884A priority patent/EP0201400B1/en
Priority to AT86400884T priority patent/ATE44734T1/en
Priority to DE8686400884T priority patent/DE3664466D1/en
Publication of FR2580638A1 publication Critical patent/FR2580638A1/en
Application granted granted Critical
Publication of FR2580638B1 publication Critical patent/FR2580638B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8506135A 1985-04-23 1985-04-23 NOVEL 4-PHENYLPROPYL INDOLE DERIVATIVES, SALTS THEREOF, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM Expired FR2580638B1 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR8506135A FR2580638B1 (en) 1985-04-23 1985-04-23 NOVEL 4-PHENYLPROPYL INDOLE DERIVATIVES, SALTS THEREOF, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM
US06/853,030 US4853408A (en) 1985-04-23 1986-04-17 4-phenylpropyl-indoles having antiarythmic activity
ZA862974A ZA862974B (en) 1985-04-23 1986-04-21 Derivatives of 4-phenylpropyl indole,their salts,process for preparing them,their use as medicaments and compositions containing them
FI861681A FI85138C (en) 1985-04-23 1986-04-22 Process for the preparation of therapeutically useful 4-phenylpropylindole derivatives
IE106386A IE59151B1 (en) 1985-04-23 1986-04-22 New derivatives of 4-phenylpropyl indole and their salts, their preparation process, their use as medicaments and the pharmaceutical compositions containing them
DK183886A DK167394B1 (en) 1985-04-23 1986-04-22 4-PHENYLPROPYLINDOL COMPOUNDS, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM
AU56492/86A AU592985B2 (en) 1985-04-23 1986-04-22 New derivatives of 4-phenylpropyl indole and their salts, their preparation process, their use as medicaments and the pharmaceutical compositions containing them
CA000507303A CA1265805A (en) 1985-04-23 1986-04-22 Preparation of novel 4- phenylpropyl indole derivatives
HU861694A HU195482B (en) 1985-04-23 1986-04-23 Process for preparing new 4-/phenyl-propyl/-indole derivatives and pharmaceutical compositions containing them
EP86400884A EP0201400B1 (en) 1985-04-23 1986-04-23 4-phenyl propyl indole derivatives and their salts, process for their preparation, their use as medicines and compositions containing them
AT86400884T ATE44734T1 (en) 1985-04-23 1986-04-23 4-PHENYLPROPYLINDOL DERIVATIVES AND THEIR SALTS, PROCESSES FOR THE PREPARATION, THEIR USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
DE8686400884T DE3664466D1 (en) 1985-04-23 1986-04-23 4-phenyl propyl indole derivatives and their salts, process for their preparation, their use as medicines and compositions containing them
JP61092469A JPS61249959A (en) 1985-04-23 1986-04-23 4-phenylpropylindole and novel derivatives of same salt, manufacture, use as drug and medicinal composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8506135A FR2580638B1 (en) 1985-04-23 1985-04-23 NOVEL 4-PHENYLPROPYL INDOLE DERIVATIVES, SALTS THEREOF, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
FR2580638A1 FR2580638A1 (en) 1986-10-24
FR2580638B1 true FR2580638B1 (en) 1987-06-12

Family

ID=9318554

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8506135A Expired FR2580638B1 (en) 1985-04-23 1985-04-23 NOVEL 4-PHENYLPROPYL INDOLE DERIVATIVES, SALTS THEREOF, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM

Country Status (3)

Country Link
JP (1) JPS61249959A (en)
FR (1) FR2580638B1 (en)
ZA (1) ZA862974B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2528043A1 (en) * 1982-06-03 1983-12-09 Roussel Uclaf NOVEL 1,3-DIHYDRO 4- / 1-HYDROXY-2-AMINO-ETHYL / 2H-INDOL-2-ONE DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME

Also Published As

Publication number Publication date
ZA862974B (en) 1987-06-24
FR2580638A1 (en) 1986-10-24
JPS61249959A (en) 1986-11-07

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Legal Events

Date Code Title Description
ST Notification of lapse