FR2571255B1 - WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS BASED ON ACID SALTS (-) CIS-1,2-EPOXYPROPYLPHOSPHONIC WITH AMINO ACIDS - Google Patents

WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS BASED ON ACID SALTS (-) CIS-1,2-EPOXYPROPYLPHOSPHONIC WITH AMINO ACIDS

Info

Publication number
FR2571255B1
FR2571255B1 FR8514800A FR8514800A FR2571255B1 FR 2571255 B1 FR2571255 B1 FR 2571255B1 FR 8514800 A FR8514800 A FR 8514800A FR 8514800 A FR8514800 A FR 8514800A FR 2571255 B1 FR2571255 B1 FR 2571255B1
Authority
FR
France
Prior art keywords
epoxypropylphosphonic
cis
water
amino acids
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8514800A
Other languages
French (fr)
Other versions
FR2571255A1 (en
Inventor
Stefania Meola
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seuref AG
Original Assignee
Seuref AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seuref AG filed Critical Seuref AG
Publication of FR2571255A1 publication Critical patent/FR2571255A1/en
Application granted granted Critical
Publication of FR2571255B1 publication Critical patent/FR2571255B1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR8514800A 1984-10-05 1985-10-07 WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS BASED ON ACID SALTS (-) CIS-1,2-EPOXYPROPYLPHOSPHONIC WITH AMINO ACIDS Expired FR2571255B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4792/84A CH660306A5 (en) 1984-10-05 1984-10-05 WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS BASED ON SALTS OF (-)CIS-1,2-EPOXYPROPYLPHOSPHONIC ACID WITH AMINO ACIDS.

Publications (2)

Publication Number Publication Date
FR2571255A1 FR2571255A1 (en) 1986-04-11
FR2571255B1 true FR2571255B1 (en) 1988-09-16

Family

ID=4282621

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8514800A Expired FR2571255B1 (en) 1984-10-05 1985-10-07 WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS BASED ON ACID SALTS (-) CIS-1,2-EPOXYPROPYLPHOSPHONIC WITH AMINO ACIDS

Country Status (11)

Country Link
JP (1) JPS62223121A (en)
KR (1) KR860003012A (en)
AT (1) AT383736B (en)
BE (1) BE903369A (en)
CH (1) CH660306A5 (en)
DE (1) DE3535356A1 (en)
ES (1) ES8609351A1 (en)
FR (1) FR2571255B1 (en)
GB (1) GB2165152B (en)
IT (1) IT1201479B (en)
NL (1) NL8502712A (en)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH310498A (en) * 1951-11-14 1955-10-31 Waldhof Zellstoff Fab Process for stabilizing alkali salts of adenosine polyphosphoric acids.
DE1767212B1 (en) * 1967-04-13 1971-05-06 Sumitomo Chemical Co Process for making injectable drugs
US3639590A (en) * 1967-07-25 1972-02-01 Merck & Co Inc Antibacterial composition containing (-) (cis-1 2-epoxypropyl) phosphoric acid
BE756953A (en) * 1969-10-02 1971-04-01 Merck & Co Inc POTENTIALIZATION OF ANTIBIOTICS
IT1161974B (en) * 1978-02-02 1987-03-18 Italchemi Spa CIS.I 2 EPOXYPROPYLPHOSPHONIC ACID DERIVATIVES THEIR PREPARATION PROCEDURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE2813814A1 (en) * 1978-03-31 1979-10-18 Boehringer Mannheim Gmbh Increasing the enteral reabsorption of pharmaceuticals - by administration together with an aminoacid or a peptide
IT1112282B (en) * 1978-07-19 1986-01-13 Zambon Spa Bis- (2-AMMONIUM-2-hydroxymethyl-1,3-propanediol) (2R-CIS) - (3-METILOSSIRANIL) phosphonate
IT1097578B (en) * 1978-07-31 1985-08-31 Italchemi Spa METHOD FOR PREPARING ACID SALTS (-)
US4235900A (en) * 1978-11-15 1980-11-25 E. R. Squibb & Sons, Inc. Cephradine compositions

Also Published As

Publication number Publication date
IT1201479B (en) 1989-02-02
NL8502712A (en) 1986-05-01
ES8609351A1 (en) 1986-09-01
JPS62223121A (en) 1987-10-01
KR860003012A (en) 1986-05-19
ATA287185A (en) 1987-01-15
ES547625A0 (en) 1986-09-01
IT8522367A0 (en) 1985-10-04
CH660306A5 (en) 1987-04-15
FR2571255A1 (en) 1986-04-11
BE903369A (en) 1986-02-03
DE3535356A1 (en) 1986-04-24
GB8524550D0 (en) 1985-11-06
GB2165152B (en) 1988-03-16
GB2165152A (en) 1986-04-09
AT383736B (en) 1987-08-10

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Legal Events

Date Code Title Description
TP Transmission of property
TP Transmission of property
ST Notification of lapse