FR2567521B1 - NEW ACTIVE IONOPHORES - Google Patents

NEW ACTIVE IONOPHORES

Info

Publication number
FR2567521B1
FR2567521B1 FR8411208A FR8411208A FR2567521B1 FR 2567521 B1 FR2567521 B1 FR 2567521B1 FR 8411208 A FR8411208 A FR 8411208A FR 8411208 A FR8411208 A FR 8411208A FR 2567521 B1 FR2567521 B1 FR 2567521B1
Authority
FR
France
Prior art keywords
ionophores
new active
active
new
active ionophores
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8411208A
Other languages
French (fr)
Other versions
FR2567521A1 (en
Inventor
Franz K Jansen
Pierre Gros
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8411208A priority Critical patent/FR2567521B1/en
Priority to CA000481505A priority patent/CA1314245C/en
Priority to IL8913885A priority patent/IL89138A/en
Priority to IL75228A priority patent/IL75228A/en
Priority to GR851229A priority patent/GR851229B/el
Priority to NZ212118A priority patent/NZ212118A/en
Priority to NZ22798585A priority patent/NZ227985A/en
Priority to EP85400998A priority patent/EP0162781B1/en
Priority to AT85400998T priority patent/ATE45092T1/en
Priority to PT80501A priority patent/PT80501B/en
Priority to DK224785A priority patent/DK164457C/en
Priority to DE8585400998T priority patent/DE3571928D1/en
Priority to IE127985A priority patent/IE58480B1/en
Priority to ES543367A priority patent/ES8604228A1/en
Priority to AU42793/85A priority patent/AU600651B2/en
Publication of FR2567521A1 publication Critical patent/FR2567521A1/en
Application granted granted Critical
Publication of FR2567521B1 publication Critical patent/FR2567521B1/en
Priority to US07/034,712 priority patent/US4919928A/en
Priority to IL89138A priority patent/IL89138A0/en
Priority to US07/457,858 priority patent/US4977280A/en
Priority to US07/458,444 priority patent/US5144009A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins
FR8411208A 1984-05-23 1984-07-13 NEW ACTIVE IONOPHORES Expired FR2567521B1 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
FR8411208A FR2567521B1 (en) 1984-07-13 1984-07-13 NEW ACTIVE IONOPHORES
CA000481505A CA1314245C (en) 1984-05-23 1985-05-14 Process for the preparation of conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule, which are useful as immunotoxin potentiators
IL8913885A IL89138A (en) 1984-05-23 1985-05-17 Activated carboxylic ionophores containing a thiol group
IL75228A IL75228A (en) 1984-05-23 1985-05-17 Conjugates in which certain nonovalent carboxylic ionophores are covalently bonded to a macromolecule,their preparation and pharmaceutical compositions containing them as immunotoxin potentiators
NZ212118A NZ212118A (en) 1984-05-23 1985-05-20 Conjugate of macromolecule and ionophore; use as immunotoxin potentiator
NZ22798585A NZ227985A (en) 1984-05-23 1985-05-20 Intermediate activated ionophores carrying a thiol group
GR851229A GR851229B (en) 1984-05-23 1985-05-20
DK224785A DK164457C (en) 1984-05-23 1985-05-21 CONJUGATES, WHICH A MONOVALENT CARBOXYLION CREATURE IS USED BY A COVALENT BINDING, TO A MACROMOLECYLE, PROCEDURE FOR THE PREPARATION OF THE CONJUGATES AND THEIR USE AS IMMUNOTO TORONOUS
AT85400998T ATE45092T1 (en) 1984-05-23 1985-05-21 CONJUGATED DERIVATIVES ASSOCIATED THROUGH COVALENT BONDS WITH A MONOVALENT CARBONYLIONOPHORE, THEIR USE AS POTENTIALIZERS OF IMMUNOTOXINS AND ACTIVATED IONOPHOROUS INTERMEDIATE COMPOUNDS.
PT80501A PT80501B (en) 1984-05-23 1985-05-21 PROCESS FOR OBTAINING CONJUGATES ASSOCIATED BY COVALENT BINDING A MONOVALENT CARBOXYLIC IONOPHORE AND A MACROMOLECULE USEFUL AS IMMUNOTOXIN POTENTIALIZING AGENTS
EP85400998A EP0162781B1 (en) 1984-05-23 1985-05-21 Conjugates associated with a covalent bond to a monovalent carboxylic ionophore and a macromolecule, their use as potentializers of immunotoxines and the activated intermediate ionophores
DE8585400998T DE3571928D1 (en) 1984-05-23 1985-05-21 Conjugates associated with a covalent bond to a monovalent carboxylic ionophore and a macromolecule, their use as potentializers of immunotoxines and the activated intermediate ionophores
IE127985A IE58480B1 (en) 1984-05-23 1985-05-22 Conjugates of monovalent carboxylic ionophores and macromolecules
ES543367A ES8604228A1 (en) 1984-05-23 1985-05-22 Conjugates associated with a covalent bond to a monovalent carboxylic ionophore and a macromolecule, their use as potentializers of immunotoxines and the activated intermediate ionophores.
AU42793/85A AU600651B2 (en) 1984-05-23 1985-05-23 Conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule, their use as immunotoxin potentiators and the intermediate activated ionophores
US07/034,712 US4919928A (en) 1984-05-23 1987-04-06 Conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule, their use as immunotoxin potentiators and the intermediate activated ionophores
IL89138A IL89138A0 (en) 1984-05-23 1989-02-01 Activated carboxylic ionophores containing a thiol group
US07/457,858 US4977280A (en) 1984-05-23 1989-12-27 Conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule, their use as immunotoxin potentiators and the intermediate activated ionophores
US07/458,444 US5144009A (en) 1984-05-23 1989-12-28 Conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule, their use as immunotoxin potentiators and the intermediate activated inophores

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8411208A FR2567521B1 (en) 1984-07-13 1984-07-13 NEW ACTIVE IONOPHORES

Publications (2)

Publication Number Publication Date
FR2567521A1 FR2567521A1 (en) 1986-01-17
FR2567521B1 true FR2567521B1 (en) 1987-01-02

Family

ID=9306132

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8411208A Expired FR2567521B1 (en) 1984-05-23 1984-07-13 NEW ACTIVE IONOPHORES

Country Status (1)

Country Link
FR (1) FR2567521B1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463144A1 (en) * 1979-08-13 1981-02-20 Syntex Inc NEW LAIDLOMYCIN DIESTERS, METHOD FOR THE PRODUCTION THEREOF, VETERINARY COMPOSITIONS CONTAINING SAME, AND USE THEREOF FOR INCREASING FOOD ASSIMILATION PERFORMANCE IN A RUMINANT
FR2498192A2 (en) * 1981-01-22 1982-07-23 Pasteur Institut NOVEL POLYPEPTIDE THIOLE COMPOUND FROM A FRAGMENT OF TETANIC TOXIN, PROCESS FOR OBTAINING SAME AND APPLICATIONS THEREOF
CA1214774A (en) * 1983-02-10 1986-12-02 Yusei Shiraga Benzodiazepine derivative

Also Published As

Publication number Publication date
FR2567521A1 (en) 1986-01-17

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Legal Events

Date Code Title Description
ST Notification of lapse