FR2549082B2 - Vecteurs perfectionnes d'expression d'une proteine ayant l'activite de l'antitrypsine-a1 humaine - Google Patents
Vecteurs perfectionnes d'expression d'une proteine ayant l'activite de l'antitrypsine-a1 humaineInfo
- Publication number
- FR2549082B2 FR2549082B2 FR8311594A FR8311594A FR2549082B2 FR 2549082 B2 FR2549082 B2 FR 2549082B2 FR 8311594 A FR8311594 A FR 8311594A FR 8311594 A FR8311594 A FR 8311594A FR 2549082 B2 FR2549082 B2 FR 2549082B2
- Authority
- FR
- France
- Prior art keywords
- activity
- expression vectors
- protein expression
- improved protein
- human antitrypsin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8125—Alpha-1-antitrypsin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/73—Expression systems using phage (lambda) regulatory sequences
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8311594A FR2549082B2 (fr) | 1983-07-12 | 1983-07-12 | Vecteurs perfectionnes d'expression d'une proteine ayant l'activite de l'antitrypsine-a1 humaine |
AT84400126T ATE55150T1 (de) | 1983-01-21 | 1984-01-20 | Expressionsvektoren und deren verwendung zur herstellung eines proteins mit menschlicher alpha-antitrypsin-aktivitaet. |
DE8484400126T DE3482840D1 (de) | 1983-01-21 | 1984-01-20 | Expressionsvektoren und deren verwendung zur herstellung eines proteins mit menschlicher alpha-antitrypsin-aktivitaet. |
CA000445727A CA1303530C (fr) | 1983-01-21 | 1984-01-20 | VECTEURS D'EXPRESSION ET LEUR UTILISATION POUR LA PREPARATION D'UNE PROTEINE AYANT UNE ACTIVITE .alpha. -ANTITRYPSINE HUMAINE |
PCT/FR1984/000014 WO1984002918A1 (fr) | 1983-01-21 | 1984-01-20 | NOUVEAUX VECTEURS D'EXPRESSION ET LEUR APPLICATION A LA PREPARATION D'UNE PROTEINE AYANT L'ACTIVITE DE L'ANTITRYPSINE-alpha1 HUMAINE |
EP84400126A EP0114777B1 (fr) | 1983-01-21 | 1984-01-20 | Nouveaux vecteurs d'expression et leur application à la préparation d'une protéine ayant l'activité de l'antitrypsine-alpha 1 humaine |
DK450584A DK450584D0 (da) | 1983-01-21 | 1984-09-20 | Ekspressionsvektorer og anvendelse deraf til fremstilling af et protein med aktiviteten af humant antitrypsin-alfa1 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8311594A FR2549082B2 (fr) | 1983-07-12 | 1983-07-12 | Vecteurs perfectionnes d'expression d'une proteine ayant l'activite de l'antitrypsine-a1 humaine |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2549082A2 FR2549082A2 (fr) | 1985-01-18 |
FR2549082B2 true FR2549082B2 (fr) | 1986-05-16 |
Family
ID=9290756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8311594A Expired FR2549082B2 (fr) | 1983-01-21 | 1983-07-12 | Vecteurs perfectionnes d'expression d'une proteine ayant l'activite de l'antitrypsine-a1 humaine |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2549082B2 (fr) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE895961A (fr) * | 1983-02-21 | 1983-06-16 | Wallone Region | Procede de preparation d'un clone bacterien produisant de 1'alpha 1-antitrypsine humaine |
-
1983
- 1983-07-12 FR FR8311594A patent/FR2549082B2/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2549082A2 (fr) | 1985-01-18 |
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