FR2500835B1 - - Google Patents

Info

Publication number
FR2500835B1
FR2500835B1 FR8103906A FR8103906A FR2500835B1 FR 2500835 B1 FR2500835 B1 FR 2500835B1 FR 8103906 A FR8103906 A FR 8103906A FR 8103906 A FR8103906 A FR 8103906A FR 2500835 B1 FR2500835 B1 FR 2500835B1
Authority
FR
France
Prior art keywords
solvent medium
hydrazine derivative
isosorbide
isosorbitol
mononitrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8103906A
Other languages
English (en)
French (fr)
Other versions
FR2500835A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe Nationale des Poudres et Explosifs
Original Assignee
Societe Nationale des Poudres et Explosifs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe Nationale des Poudres et Explosifs filed Critical Societe Nationale des Poudres et Explosifs
Priority to FR8103906A priority Critical patent/FR2500835A1/fr
Priority to IN113/DEL/82A priority patent/IN157599B/en
Priority to US06/349,073 priority patent/US4381400A/en
Priority to ES509741A priority patent/ES8302716A1/es
Priority to CA000397069A priority patent/CA1182829A/en
Priority to AT82400328T priority patent/ATE10371T1/de
Priority to DE8282400328T priority patent/DE3261256D1/de
Priority to EP82400328A priority patent/EP0059664B1/fr
Priority to IE428/82A priority patent/IE52602B1/en
Priority to JP57029107A priority patent/JPS57156492A/ja
Priority to HU82603A priority patent/HU191346B/hu
Publication of FR2500835A1 publication Critical patent/FR2500835A1/fr
Application granted granted Critical
Publication of FR2500835B1 publication Critical patent/FR2500835B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR8103906A 1981-02-27 1981-02-27 Procede de synthese des mononitrates d'isosorbide Granted FR2500835A1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR8103906A FR2500835A1 (fr) 1981-02-27 1981-02-27 Procede de synthese des mononitrates d'isosorbide
IN113/DEL/82A IN157599B (enExample) 1981-02-27 1982-02-11
US06/349,073 US4381400A (en) 1981-02-27 1982-02-16 Process for the synthesis of isosorbide mononitrates
ES509741A ES8302716A1 (es) 1981-02-27 1982-02-19 "procedimiento de sintesis de mononitratos de isosorbido".
AT82400328T ATE10371T1 (de) 1981-02-27 1982-02-25 Verfahren zur herstellung von isosorbidmononitraten.
DE8282400328T DE3261256D1 (en) 1981-02-27 1982-02-25 Process for the preparation of isosorbide mononitrates
CA000397069A CA1182829A (en) 1981-02-27 1982-02-25 Process for the synthesis of isosorbide mononitrates
EP82400328A EP0059664B1 (fr) 1981-02-27 1982-02-25 Procédé de synthèse des mononitrates d'isosorbide
IE428/82A IE52602B1 (en) 1981-02-27 1982-02-26 Process for the synthesis of isosorbide mononitrates
JP57029107A JPS57156492A (en) 1981-02-27 1982-02-26 Manufacture of isosorbidomononitrate
HU82603A HU191346B (en) 1981-02-27 1982-02-26 Process for preparing isosorbide-mononitrate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8103906A FR2500835A1 (fr) 1981-02-27 1981-02-27 Procede de synthese des mononitrates d'isosorbide

Publications (2)

Publication Number Publication Date
FR2500835A1 FR2500835A1 (fr) 1982-09-03
FR2500835B1 true FR2500835B1 (enExample) 1983-10-21

Family

ID=9255675

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8103906A Granted FR2500835A1 (fr) 1981-02-27 1981-02-27 Procede de synthese des mononitrates d'isosorbide

Country Status (11)

Country Link
US (1) US4381400A (enExample)
EP (1) EP0059664B1 (enExample)
JP (1) JPS57156492A (enExample)
AT (1) ATE10371T1 (enExample)
CA (1) CA1182829A (enExample)
DE (1) DE3261256D1 (enExample)
ES (1) ES8302716A1 (enExample)
FR (1) FR2500835A1 (enExample)
HU (1) HU191346B (enExample)
IE (1) IE52602B1 (enExample)
IN (1) IN157599B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3124410A1 (de) * 1981-06-22 1983-01-05 Heinrich Mack Nachf., 7918 Illertissen Verfahren zur herstellung von isosorbid-2-nitrat
JPS60149521A (ja) * 1984-01-18 1985-08-07 Eisai Co Ltd 高眼圧・緑内障治療・予防用点眼剤
EP0266450B1 (en) * 1986-11-05 1992-01-15 Consiglio Nazionale Delle Ricerche Process for the selective preparation of isosorbide-2-mononitrate from isosorbide-2,5-dinitrate
IT1208537B (it) * 1985-05-10 1989-07-10 Consiglio Nazionale Ricerche Processo per la preparazione dell'isosorbide-5-monoidrato.
EP0201067B1 (en) * 1985-05-10 1991-08-07 Consiglio Nazionale Delle Ricerche Process for the preparation of isosorbide-5-mononitrate
FR2601386B1 (fr) * 1986-07-11 1988-11-18 Centre Nat Rech Scient Procede de bioconversion selective du dinitrate d'isosorbitol
DE4410997A1 (de) * 1994-03-30 1995-10-26 Isis Pharma Gmbh Pharmazeutische Zubereitungen und Arzneistoffe zur Prävention und Behandlung endothelialer Dysfunktionen
IT1311986B1 (it) * 1999-03-26 2002-03-22 Dinamite Dipharma S P A In For Procedimento per la preparazione di monoesteri nitrici di compostidiidrossialchilici e diidrossicicloalchilici.
GB9930778D0 (en) * 1999-12-29 2000-02-16 Archimici Ltd Compound synthesis
DE102008050597A1 (de) 2008-10-09 2010-04-15 Actavis Deutschland Gmbh & Co. Kg Pharmazeutische Zubereitungen zur Anwendung in einem Verfahren zur therapeutischen Behandlung von Hörsturz
CN104892623B (zh) * 2015-06-11 2017-08-11 山东新时代药业有限公司 一种5‑单硝酸异山梨酯的制备方法
CN113105470A (zh) * 2021-03-15 2021-07-13 海南通用康力制药有限公司 单硝酸异山梨酯的合成方法及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886186A (en) * 1971-04-29 1975-05-27 American Home Prod Mononitrate esters of 1,4:3,6-dianhydro-d-glucitol

Also Published As

Publication number Publication date
HU191346B (en) 1987-02-27
EP0059664A1 (fr) 1982-09-08
IE52602B1 (en) 1987-12-23
IE820428L (en) 1982-08-27
EP0059664B1 (fr) 1984-11-21
CA1182829A (en) 1985-02-19
ES509741A0 (es) 1983-02-01
US4381400A (en) 1983-04-26
JPS57156492A (en) 1982-09-27
IN157599B (enExample) 1986-05-03
ES8302716A1 (es) 1983-02-01
ATE10371T1 (de) 1984-12-15
DE3261256D1 (en) 1985-01-03
FR2500835A1 (fr) 1982-09-03

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Legal Events

Date Code Title Description
ST Notification of lapse