FR2500755B1 - - Google Patents

Info

Publication number
FR2500755B1
FR2500755B1 FR8200025A FR8200025A FR2500755B1 FR 2500755 B1 FR2500755 B1 FR 2500755B1 FR 8200025 A FR8200025 A FR 8200025A FR 8200025 A FR8200025 A FR 8200025A FR 2500755 B1 FR2500755 B1 FR 2500755B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8200025A
Other versions
FR2500755A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of FR2500755A1 publication Critical patent/FR2500755A1/fr
Application granted granted Critical
Publication of FR2500755B1 publication Critical patent/FR2500755B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
FR8200025A 1981-01-05 1982-01-04 Compositions de plasmine stabilisee, leur procede de preparation et leurs applications, notamment comme agents de balayage scintigraphique Granted FR2500755A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8100133 1981-01-05

Publications (2)

Publication Number Publication Date
FR2500755A1 FR2500755A1 (fr) 1982-09-03
FR2500755B1 true FR2500755B1 (fr) 1984-01-13

Family

ID=10518790

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8200025A Granted FR2500755A1 (fr) 1981-01-05 1982-01-04 Compositions de plasmine stabilisee, leur procede de preparation et leurs applications, notamment comme agents de balayage scintigraphique

Country Status (8)

Country Link
US (1) US4462980A (fr)
BE (1) BE891679A (fr)
CH (1) CH648862A5 (fr)
DE (1) DE3200058A1 (fr)
DK (1) DK982A (fr)
FR (1) FR2500755A1 (fr)
IT (1) IT1194135B (fr)
NL (1) NL8200004A (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816568A (en) * 1986-05-16 1989-03-28 International Minerals & Chemical Corp. Stabilization of growth hormones
US5288489A (en) * 1991-08-28 1994-02-22 Orion Therapeutic Systems, Inc. Fibrinolysis and fibrinogenolysis treatment
US6964764B2 (en) * 1999-11-13 2005-11-15 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US6355243B1 (en) * 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US7544500B2 (en) * 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6969515B2 (en) 1999-11-13 2005-11-29 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
EP1337548B1 (fr) * 2000-11-28 2008-07-16 David M. Waisman Polypeptides anti-angiogeniques
US20040142897A1 (en) * 2001-11-28 2004-07-22 Waisman David M. Compositions and methods for inhibiting tumor growth and metastasis
AU2002357017A1 (en) * 2001-11-28 2003-06-10 Mediomics, Llc Anti-angiogenesis methods, compositions and uses therefor
GB0228409D0 (en) 2002-12-06 2003-01-08 Thromb X Nv Pharmacological vitreolysis
EP1581164A4 (fr) 2002-12-13 2008-03-12 Mediomics Llc Compositions et methodes d'inhibition de la croissance des tumeurs et des metastases
KR20080022108A (ko) * 2005-06-14 2008-03-10 니혼 메디피직스 가부시키가이샤 방사성 화상 진단제
US8617863B2 (en) * 2008-06-04 2013-12-31 Grifols Therapeutics Inc. Composition, method, and kit for preparing plasmin
US9206410B2 (en) 2009-03-03 2015-12-08 Grifols Therapeutics Inc. Compositions, methods and kits for preparing plasminogen and plasmin prepared therefrom
NZ597452A (en) 2009-07-10 2013-10-25 Thrombogenics Nv Variants of plasminogen and plasmin
AU2012204874B9 (en) 2011-01-05 2014-10-30 Thrombogenics Nv Plasminogen and plasmin variants
EP2741767A1 (fr) 2011-08-12 2014-06-18 ThromboGenics N.V. Variants du plasminogène et de la plasmine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950513A (en) * 1965-12-03 1976-04-13 Novo Terapeutisk Laboratorium A/S Process of stabilizing therapeutically useful plasmin solutions
US3720761A (en) * 1968-10-14 1973-03-13 W Hunter Injectable radio-pharmaceutical scanning agent and preparation
US3863004A (en) * 1972-03-20 1975-01-28 Mallinckrodt Chemical Works Denatured macroprotein with divalent tin for tagging with technetium-99m and method of preparation
US4048296A (en) * 1975-05-27 1977-09-13 Mallinckrodt, Inc. Radiopharmaceutical scanning agents
US4062933A (en) * 1975-05-27 1977-12-13 Mallinckrodt, Inc. Colloidal compositions with protective agents suitable for radioactive labeling
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
US4462980A (en) 1984-07-31
CH648862A5 (de) 1985-04-15
DE3200058A1 (de) 1982-11-04
BE891679A (fr) 1982-07-05
FR2500755A1 (fr) 1982-09-03
NL8200004A (nl) 1982-08-02
IT1194135B (it) 1988-09-14
IT8125932A0 (it) 1981-12-31
DK982A (da) 1982-07-06

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Legal Events

Date Code Title Description
ST Notification of lapse