FR24C1000I1 - MULTIMODAL RELEASE FORMULATION BASED ON DOXYLAMINE AND PYRIDOXINE AND/OR METABOLITES OR ASSOCIATED SALTS - Google Patents
MULTIMODAL RELEASE FORMULATION BASED ON DOXYLAMINE AND PYRIDOXINE AND/OR METABOLITES OR ASSOCIATED SALTSInfo
- Publication number
- FR24C1000I1 FR24C1000I1 FR24C1000C FR24C1000C FR24C1000I1 FR 24C1000 I1 FR24C1000 I1 FR 24C1000I1 FR 24C1000 C FR24C1000 C FR 24C1000C FR 24C1000 C FR24C1000 C FR 24C1000C FR 24C1000 I1 FR24C1000 I1 FR 24C1000I1
- Authority
- FR
- France
- Prior art keywords
- doxylamine
- pyridoxine
- metabolites
- release formulation
- formulation based
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 title 2
- HCFDWZZGGLSKEP-UHFFFAOYSA-N doxylamine Chemical compound C=1C=CC=NC=1C(C)(OCCN(C)C)C1=CC=CC=C1 HCFDWZZGGLSKEP-UHFFFAOYSA-N 0.000 title 1
- 229960005178 doxylamine Drugs 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000002207 metabolite Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 235000008160 pyridoxine Nutrition 0.000 title 1
- 239000011677 pyridoxine Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 229940011671 vitamin b6 Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CA2014/050828 WO2016029290A1 (en) | 2014-08-29 | 2014-08-29 | Plurimodal release formulation of doxylamine and pyridoxine and/or metabolites or salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR24C1000I1 true FR24C1000I1 (en) | 2024-02-23 |
Family
ID=55398524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR24C1000C Active FR24C1000I1 (en) | 2014-08-29 | 2024-01-04 | MULTIMODAL RELEASE FORMULATION BASED ON DOXYLAMINE AND PYRIDOXINE AND/OR METABOLITES OR ASSOCIATED SALTS |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP3185856B1 (en) |
| JP (1) | JP6272561B2 (en) |
| KR (1) | KR101831570B1 (en) |
| CN (1) | CN106794148B (en) |
| AR (1) | AR101728A1 (en) |
| AU (1) | AU2014405049B2 (en) |
| CA (1) | CA2920247C (en) |
| CY (1) | CY1120788T1 (en) |
| DK (1) | DK3185856T3 (en) |
| EA (1) | EA032671B1 (en) |
| ES (1) | ES2674996T3 (en) |
| FR (1) | FR24C1000I1 (en) |
| HU (1) | HUE038969T2 (en) |
| IL (1) | IL250541B (en) |
| MX (1) | MX360662B (en) |
| MY (1) | MY196073A (en) |
| PH (1) | PH12017500282A1 (en) |
| PL (1) | PL3185856T3 (en) |
| PT (1) | PT3185856T (en) |
| SA (1) | SA517380942B1 (en) |
| SG (1) | SG11201701448XA (en) |
| TR (1) | TR201809565T4 (en) |
| UA (1) | UA118711C2 (en) |
| WO (1) | WO2016029290A1 (en) |
| ZA (1) | ZA201701063B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2847648T3 (en) | 2018-09-27 | 2021-08-03 | Inibsa Ginecologia S A | Procedure for the preparation of a multiple unit modified release oral dosage form of doxylamine succinate and pyridoxine hydrochloride |
| AR121619A1 (en) | 2020-03-25 | 2022-06-22 | Inibsa Ginecologia S A | A MULTIPLE MODIFIED RELEASE UNIT ORAL DOSAGE FORM OF DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE AND A PROCEDURE FOR THEIR PREPARATION |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2772615B1 (en) * | 1997-12-23 | 2002-06-14 | Lipha | MULTILAYER TABLET FOR INSTANT RELEASE THEN PROLONGED ACTIVE SUBSTANCES |
| CA2350195C (en) * | 2000-12-20 | 2003-06-10 | Duchesnay Inc. | Rapid onset formulation of pyridoxine hydrochloride and doxylamine succinate |
| TWI292138B (en) * | 2004-03-11 | 2008-01-01 | Mstar Semiconductor Inc | Device for adaptively adjusting video's luminance and related method |
| EP1814527B2 (en) * | 2004-11-05 | 2020-11-18 | Boehringer Ingelheim International GmbH | Bilayer tablet comprising telmisartan and amlodipine |
| AR075880A1 (en) * | 2009-03-20 | 2011-05-04 | Novartis Ag | GALENIC FORMULATIONS OF ORGANIC COMPOUNDS THAT INCLUDE ALISQUIRENO AND VALSARTAN. USE. METHOD. |
| EP2500016A1 (en) * | 2011-03-18 | 2012-09-19 | Laboratorios Del. Dr. Esteve, S.A. | Doxylamine resinate complex |
| CA2761212A1 (en) * | 2011-12-07 | 2013-06-07 | Pharmascience Inc. | Disintegrant-free delayed release doxylamine and pyridoxine formulation and process of it manufacturing |
| SG11201403931YA (en) * | 2012-02-22 | 2014-08-28 | Duchesnay Inc | Formulation of doxylamine and pyridoxine and/or metabolites or salts thereof |
| WO2013123569A1 (en) * | 2012-02-22 | 2013-08-29 | Duchesnay Inc. | Formulation of doxylamine and pyridoxine and/or metabolites or salts thereof |
-
2014
- 2014-08-29 WO PCT/CA2014/050828 patent/WO2016029290A1/en active Application Filing
- 2014-08-29 DK DK14900963.1T patent/DK3185856T3/en active
- 2014-08-29 HU HUE14900963A patent/HUE038969T2/en unknown
- 2014-08-29 EP EP14900963.1A patent/EP3185856B1/en active Active
- 2014-08-29 KR KR1020177008120A patent/KR101831570B1/en active IP Right Grant
- 2014-08-29 UA UAA201702935A patent/UA118711C2/en unknown
- 2014-08-29 CN CN201480081512.3A patent/CN106794148B/en active Active
- 2014-08-29 EA EA201790477A patent/EA032671B1/en unknown
- 2014-08-29 JP JP2017511764A patent/JP6272561B2/en active Active
- 2014-08-29 MY MYPI2017700682A patent/MY196073A/en unknown
- 2014-08-29 ES ES14900963.1T patent/ES2674996T3/en active Active
- 2014-08-29 MX MX2017002495A patent/MX360662B/en active IP Right Grant
- 2014-08-29 SG SG11201701448XA patent/SG11201701448XA/en unknown
- 2014-08-29 CA CA2920247A patent/CA2920247C/en active Active
- 2014-08-29 TR TR2018/09565T patent/TR201809565T4/en unknown
- 2014-08-29 AU AU2014405049A patent/AU2014405049B2/en active Active
- 2014-08-29 PL PL14900963T patent/PL3185856T3/en unknown
- 2014-08-29 PT PT14900963T patent/PT3185856T/en unknown
-
2015
- 2015-08-31 AR ARP150102789A patent/AR101728A1/en not_active Application Discontinuation
-
2017
- 2017-02-09 IL IL250541A patent/IL250541B/en active IP Right Grant
- 2017-02-13 ZA ZA201701063A patent/ZA201701063B/en unknown
- 2017-02-15 PH PH12017500282A patent/PH12017500282A1/en unknown
- 2017-02-21 SA SA517380942A patent/SA517380942B1/en unknown
-
2018
- 2018-08-10 CY CY20181100842T patent/CY1120788T1/en unknown
-
2024
- 2024-01-04 FR FR24C1000C patent/FR24C1000I1/en active Active
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