FR2491469B1 - - Google Patents

Info

Publication number
FR2491469B1
FR2491469B1 FR8021095A FR8021095A FR2491469B1 FR 2491469 B1 FR2491469 B1 FR 2491469B1 FR 8021095 A FR8021095 A FR 8021095A FR 8021095 A FR8021095 A FR 8021095A FR 2491469 B1 FR2491469 B1 FR 2491469B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8021095A
Other versions
FR2491469A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Priority to FR8021095A priority Critical patent/FR2491469A1/fr
Priority to FR8106916A priority patent/FR2503155A2/fr
Priority to IL63940A priority patent/IL63940A/xx
Priority to MX10162481U priority patent/MX6654E/es
Priority to IE2257/81A priority patent/IE51821B1/en
Priority to DE8181401501T priority patent/DE3164201D1/de
Priority to LU88262C priority patent/LU88262I2/xx
Priority to AT81401501T priority patent/ATE7910T1/de
Priority to EP81401501A priority patent/EP0049658B1/fr
Priority to FI813034A priority patent/FI77230C/fi
Priority to AR81286934A priority patent/AR242949A1/es
Priority to EG556/81A priority patent/EG15361A/xx
Priority to DZ816331A priority patent/DZ327A1/fr
Priority to MA19495A priority patent/MA19294A1/fr
Priority to AU75949/81A priority patent/AU542611B2/en
Priority to DK434381A priority patent/DK157011C/da
Priority to PT73755A priority patent/PT73755B/fr
Priority to UA3344196A priority patent/UA6308A1/uk
Priority to PH26297A priority patent/PH17516A/en
Priority to CA000387093A priority patent/CA1341196C/fr
Priority to OA57509A priority patent/OA06914A/fr
Priority to GR66179A priority patent/GR75016B/el
Priority to NO813339A priority patent/NO160780C/no
Priority to HU812838A priority patent/HU185147B/hu
Priority to DD81233794A priority patent/DD201783A5/de
Priority to YU2366/81A priority patent/YU43720B/xx
Priority to SU813344196A priority patent/SU1153827A3/ru
Priority to KR1019810003709A priority patent/KR860001875B1/ko
Priority to ZA816844A priority patent/ZA816844B/xx
Priority to US06/308,234 priority patent/US4508729A/en
Priority to NZ198535A priority patent/NZ198535A/en
Priority to JP56157367A priority patent/JPS5791974A/ja
Priority to ES505999A priority patent/ES8305723A1/es
Publication of FR2491469A1 publication Critical patent/FR2491469A1/fr
Priority to US06/420,005 priority patent/US4565819A/en
Application granted granted Critical
Publication of FR2491469B1 publication Critical patent/FR2491469B1/fr
Priority to US06/659,276 priority patent/US4616031A/en
Priority to US06/659,274 priority patent/US4644008A/en
Priority to US06/659,275 priority patent/US4616029A/en
Priority to US06/679,320 priority patent/US4616030A/en
Priority to NL930046C priority patent/NL930046I2/nl
Priority to LTRP981A priority patent/LT2504B/xx
Priority to LV931141A priority patent/LV5484A3/xx
Priority to GEAP19941926A priority patent/GEP19970943B/en
Priority to MD95-0107A priority patent/MD381C2/ro
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8021095A 1979-12-07 1980-10-02 Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme Granted FR2491469A1 (fr)

Priority Applications (43)

Application Number Priority Date Filing Date Title
FR8021095A FR2491469A1 (fr) 1980-10-02 1980-10-02 Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR8106916A FR2503155A2 (fr) 1980-10-02 1981-04-07 Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
IL63940A IL63940A (en) 1980-10-02 1981-09-25 N-acyl carboxy perhydroindoles or perhydroisoquinolines,their preparation and pharmaceutical compositions containing them
MX10162481U MX6654E (es) 1980-10-02 1981-09-28 Procedimiento de preparacion de acidos azabicicloalcanodicarboxilicos sustituidos
IE2257/81A IE51821B1 (en) 1980-10-02 1981-09-29 Substituted imino-diacids,their preparation and pharmaceutical compositions containing them
DE8181401501T DE3164201D1 (en) 1980-10-02 1981-09-29 Substituted imino diacids, their preparation and pharmaceutical preparations containing them
LU88262C LU88262I2 (fr) 1980-10-02 1981-09-29
AT81401501T ATE7910T1 (de) 1980-10-02 1981-09-29 Substituierte iminodisaeuren, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
EP81401501A EP0049658B1 (fr) 1980-10-02 1981-09-29 Iminodiacides substitués, leur préparation et compositions pharmaceutiques les contenant
AR81286934A AR242949A1 (es) 1980-10-02 1981-09-30 Procedimiento de preparacion de nuevos n¡(carboxialquilamino)acil¿amino acidos biciclicos.
EG556/81A EG15361A (en) 1980-10-02 1981-09-30 Nouveaux amino diacides substituted,leur procede dnouveaux amino diacides substitues,leurs procedes e preparation et leur empoi comme inhibiteur d'enzde preparation et leur emploi comme inhibiteur d'eime nzyme
DZ816331A DZ327A1 (fr) 1980-10-02 1981-09-30 Imino diacides substitutes, leur préparation e composition pharmaceutiques les contenant.
MA19495A MA19294A1 (fr) 1980-10-02 1981-09-30 Procede de preparation d'imino-diacides substitues.
FI813034A FI77230C (fi) 1980-10-02 1981-09-30 Foerfarande foer framstaellning av substituerade perhydroindoliminodisyror med antihypertensiv aktivitet.
HU812838A HU185147B (en) 1980-10-02 1981-10-01 Process for the preparation of aza-bicyclo-alkan-dicarboxylic acid derivatives
PT73755A PT73755B (fr) 1980-10-02 1981-10-01 Procede de preparation d'imino diacides substitues
UA3344196A UA6308A1 (uk) 1980-10-02 1981-10-01 Спосіб одержання заміщених амінокислот, їх рацематів або оптичних ізомерів, або їх фармацевтично прийнятних солей
PH26297A PH17516A (en) 1980-10-02 1981-10-01 Substituted iminodiacids,their preparation and pharmaceutical composition containing them
CA000387093A CA1341196C (fr) 1980-10-02 1981-10-01 Procede de preparation d'imino diacides substitues
OA57509A OA06914A (fr) 1980-10-02 1981-10-01 Procédé de préparation d'iminodiacides substitués.
GR66179A GR75016B (fr) 1980-10-02 1981-10-01
NO813339A NO160780C (no) 1980-10-02 1981-10-01 Analogifremgangsmaate ved fremstilling av substituerte iminodisyrer.
AU75949/81A AU542611B2 (en) 1980-10-02 1981-10-01 Indole and isoquinoline derivatives
DD81233794A DD201783A5 (de) 1980-10-02 1981-10-01 Verfahren zur herstellung von substituierten zweibasischen iminosaeuren
DK434381A DK157011C (da) 1980-10-02 1981-10-01 Analogifremgangsmaade til fremstilling af 2-carboxy-perhydroindolderivater
SU813344196A SU1153827A3 (ru) 1980-10-02 1981-10-01 Способ получени замещенных аминодикислот,их рацематов или оптических изомеров,или их фармацевтически приемлемых солей
YU2366/81A YU43720B (en) 1980-10-02 1981-10-01 Process for producing substituted iminodiacids
KR1019810003709A KR860001875B1 (ko) 1980-10-02 1981-10-02 치환된 아미노이산의 제조방법
ZA816844A ZA816844B (en) 1980-10-02 1981-10-02 Substituted iminodiacids,their preparation and pharmaceutical compositions containing them
US06/308,234 US4508729A (en) 1979-12-07 1981-10-02 Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
NZ198535A NZ198535A (en) 1980-10-02 1981-10-02 Substituted azabicycloalkanedicarboxylic acids and pharmaceutical compositions containing such
JP56157367A JPS5791974A (en) 1980-10-02 1981-10-02 Imino diacid compound, manufacture and medicinal composition containing same as active component
ES505999A ES8305723A1 (es) 1980-10-02 1981-10-02 Procedimiento de preparacion de nuevos imino diacidos susti-tuidos y de sus sales
US06/420,005 US4565819A (en) 1979-12-07 1982-09-20 Substituted imino diacids, their preparation and pharmaceutical compositions which contain them
US06/659,275 US4616029A (en) 1979-12-07 1984-10-10 Perhydromdole-2-carboxylic acids as antihypertensives
US06/659,276 US4616031A (en) 1979-12-07 1984-10-10 Perhydroindole-2-carboxylic acids as antihypertensives
US06/659,274 US4644008A (en) 1979-12-07 1984-10-10 Perhydroindole-2-carboxylic acids as antihypertensives
US06/679,320 US4616030A (en) 1979-12-07 1984-12-06 Perhydroindole-2-carboxylic acids as antihypertensives
NL930046C NL930046I2 (nl) 1980-10-02 1993-06-01 Gesubstitueerde iminodizuren, hun bereiding en henbevattende farmaceutische mengsels.
LTRP981A LT2504B (lt) 1980-10-02 1993-09-16 Pakeistu aminodirugsciu, ju racematu arba optiniu izomeru. arba ju farmaciskai priimtinu drusku gavimo budas
LV931141A LV5484A3 (lv) 1980-10-02 1993-10-08 Panemiens aizvietotu aminodikarbonskabju to racematu vai optisko izomeru vai to farmaceitiski pienemamo salu iegusanai
GEAP19941926A GEP19970943B (en) 1980-10-02 1994-05-16 Method of obtaining substituted aminodiacids,their racemates or optical isomers,or their pharmaceutically acceptable salts
MD95-0107A MD381C2 (ro) 1980-10-02 1994-12-29 Procedeu de obţinere a aminodiacizilor substituiţi, racematelor sau izomerilor lor optici, sau sărurilor lor farmaceutic admisibile

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8021095A FR2491469A1 (fr) 1980-10-02 1980-10-02 Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme

Publications (2)

Publication Number Publication Date
FR2491469A1 FR2491469A1 (fr) 1982-04-09
FR2491469B1 true FR2491469B1 (fr) 1983-05-13

Family

ID=9246484

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8021095A Granted FR2491469A1 (fr) 1979-12-07 1980-10-02 Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme

Country Status (6)

Country Link
DZ (1) DZ327A1 (fr)
FR (1) FR2491469A1 (fr)
LT (1) LT2504B (fr)
MA (1) MA19294A1 (fr)
YU (1) YU43720B (fr)
ZA (1) ZA816844B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
US4483850A (en) * 1982-05-10 1984-11-20 Merck & Co., Inc. N-Terminal substituted oligopeptide converting enzyme inhibitors
DE3242151A1 (de) * 1982-11-13 1984-05-17 Hoechst Ag, 6230 Frankfurt Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
GB8311286D0 (en) * 1983-04-26 1983-06-02 Searle & Co Carboxyalkyl peptide derivatives
DE3333454A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0018104B1 (fr) * 1979-03-26 1983-05-25 Takeda Chemical Industries, Ltd. Dérivés de la tétrahydro-isoquinoléine, leur préparation, dérivés et compositions pharmaceutiques les contenant pour utilisation dans la prévention et dans le traitement de l'hypertension

Also Published As

Publication number Publication date
YU43720B (en) 1989-10-31
FR2491469A1 (fr) 1982-04-09
YU236681A (en) 1983-09-30
ZA816844B (en) 1982-09-29
DZ327A1 (fr) 2004-09-13
LT2504B (lt) 1994-02-15
MA19294A1 (fr) 1982-04-01

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Legal Events

Date Code Title Description
TP Transmission of property