FR2470998A1 - ASSESSMENT ASSESSMENT FOR CALCULATING PARAMETERS - Google Patents

Abstract

THE PRESENT INVENTION CONCERNS AN ASSESSMENT ASSISTANT FOR CALCULATING LIPID PARAMETERS. THIS AUXILIARY IS CONSISTING OF TWO SCALE GROUPS WITH EACH TIME TWO SCALES FIXED TO ONE ANOTHER, OR ONE SCALE GROUP CONTAINS THE CONCENTRATION GRADUATIONS FOR TRIGLYCERIDES AND HDL-CHOLESTEROL, THE OTHER FOR TOTAL CHOLESTEROL AND LDL-CHOLESTEROL, AND WHERE ONE OF THE SCALE GROUPS IS AVAILABLE IN A MANNER THAT IT CAN MOVE IN RELATION TO THE OTHER. APPLICATION TO MEDICAL ANALYSIS.

Description

-1 -

  The present invention relates to an auxiliary

  evaluation for the calculation of lipid parameters

c.

  In blood or serum, cholesterol

  terol occurs in various lipoprotein fractions, all of which have different meanings in clinical diagnosis. LDL cholesterol (LDL = low density lipoprotein or low density lipoprotein)

  increases the risk of lesions

  blood cholesterol, HDL-cholesterol (HDL = high density lipoprotein or high-density lipoprotein)

  drop. The determination of HDL-cholesterol is pos-

  in a simple way with methods of precipitation

  while there is no known determination

  direct analogous simplicity for LDL-choles-

  terol. There is, however, a formula for approximating the calculation of LDL cholesterol according to which the LDL-cholesterol content corresponds to the total cholesterol content, less the HDL-cholesterol content, minus one-fifth of the triglyceride content.

  (Friedewald et al., Clin Chem 18, 499 (1972)).

  But whatever the simplicity of this relationship, its continual application is very

  tedious. That is why we have already proposed a

  gram for the determination of LDL-cholesterol. This nomogram contains five vertical lines, one close

  on the other separated by determined intervals.

  Four of these lines contain concentration gradations for LDL-cholesterol, total cholesterol, triglycerides or HDL cholesterol, and the fifth line is an auxiliary line that is

  between the triglyceride line and that of the HDL-

  cholesterol. For evaluation, the points are linked

  corresponding to results of measurements on the scales

  Triglycerides and HDL-cholesterol with a straight line; we get a point of intersection with the auxiliary line. This point of intersection and the point corresponding to the measurement result on the cholesterol scale are connected with a second line.

  This line is extended up to the LDL-

  cholesterol; at the point of intersection on this scale

  the concentration of LDL-cholesterol corre-

ponding.

  Although the determination of LDL-choles-

  tol using the nomogram represents a great simplification compared to the calculation, this method however takes time and includes a whole series of possibilities of errors especially for people who are not used to it because it is necessary to record three measures and build two straight before you can

  read the desired scan value.

  The invention responds to the need to create an evaluation aid for the calculation of parameters

  lipids that reduce the overall calorie

  ass to a simple process of setting and reading.

  The subject of the invention is an evaluation aid for calculating lipid parameters, consisting of two groups of scales with two scales each fixedly linked to one another, where one of the groups of scales includes graduations

  of concentration for triglycerides and HDL-

  cholesterol, the other for total cholesterol and LDL-cholesterol, and o one of the groups of scales

  is so arranged as to be able to move about

  port to another. The group of ladders with scales

  separated for total cholesterol and LDL-cholesterol

  rol can also be collected in one scale.

  Ladder groups are preferably -3-

  arranged on two disks linked to each other, arround-

  say, being rotatable relative to each other and of different diameter, the scales being arranged in the form of segments of a circle. It is of course also possible to give the lower disk a square or polygonal shape or to have the groups

  ladders on two devices of the

  gular that can move relative to each other.

  The scale of graduation (angle / unit of

  concentration or length / unit of concentration

  mass concentration) for the three scales of cholesterol, HDLcholesterol and LDL-cholesterol is the same;

  scale scale for the triglyceride scale.

  is one-fifth of the scale of three

  other sizes. The concentration range is

  presented on the scales results from the required reading accuracy and the clinically significant concentration range; for cholesterol, there is at least a range of from 200 to 300 mg / dl, for triglycerides of 50 to 400 mg / dl, for HDL-cholesterol of 10 to 100 mg / dl and for LDL-cholesterol of 120 at 200 mg / dl. Instead of being

  graduated in the usual units (mg / dl) the scales

  they can also be in other units such as mg / l, g / l, mol / l or mmol / l. Additional indications for clinical interpretation such as normal range or risk factors are

also possible.

  The dimensions of the assessment assistant

  according to the invention are determined to have

  sufficient reading accuracy and manageability

  and may vary widely.

  valle. The circular embodiment has for example

  a diameter of about 6 to 20 cm; the form of

  The rectangular section preferably has a size of

3 x 10 cm to 5 x 30 cm.

  The drawings show the preferred embodiments of the evaluation aid according to the invention. Figure 1 shows a circular embodiment, Figures 2 and 3 a

of rectangular realization.

  The circular shape represented on the

  Figure 1 consists of two disks linked to each other

  be in their center and able to turn one

  port to the other, the lower disk being a little larger, so that one can see its graduations over the edge of the upper disk. This lower disc contains the scales for total cholesterol and LDL-cholesterol; in both cases, the concentration units increase in a clockwise direction. The top disk contains

  the scales for HDL-cholesterol and triglycerides

  cerides, the concentration units for HDL-

  increasing cholesterol in the opposite direction of

  guilles of a watch, but corresponding exactly to the measurement of concentration of LDL-cholesterol and total cholesterol, while the units of concentration for triglycerides increase in a clockwise direction and that the measurement of concentration s' pupil at the fifth of that of

other parameters.

  Figure 2 shows a rectangular shape

  depending on the type of a slide rule.

  The two outer scales (LDL-cho-

  and the two inner scales (HDL cholesterol and triglyceride) are fixedly connected to one another and can move relative to each other. The units of concentration increase from left to right, with the exception of those of triglycerides. Figure 3 shows the scales of total cholesterol and LDL-cholesterol in a single scale. Figures 1b, 2b and 3b show sections of Figures 1a,

2a and 3a.

  Determination of LDL-cholesterol

  first by searching in a sample of

  Serum total cholesterol, triglycerides and HDL cholesterol by known methods. In the case of the circular embodiment according to FIG. 1, the discs are then placed so that the points which represent the concentration in

  triglyceride and cholesterol on the correct scales.

  Respondents are facing each other. The point corresponding to the measurement result is then searched on the HDL-cholesterol scale and the result is the concentration of LDL-cholesterol.

located opposite this point.

  Figure 2 shows the

  assigned LDL-cholesterol determination, and the following analysis results are taken as a basis:

  Total cholesterol 260 mg / dl, HDL-choles-

  40 mg / dl, triglyceride 200 mg / dl. The value 260 is then taken to the total cholesterol scale.

  face of the value 40 on the HDL-cholesterol scale.

  On the scale of triglycerides connected in a fixed way on the HDL cholesterol scale, the value is sought; on the LDL-cholesterol scale at the place opposite that value, we read the value

  sought: 180 mg / dl of LDL-cholesterol.

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Claims (6)

  1. Evaluation aid for the calculation of lipid parameters, consisting of two groups of scales with two scales permanently connected to each other in a fixed manner, o a group of scales containing the concentration gradations for triglycerides and HDL cholesterol, the other for total cholesterol and LDL-cholesterol, and where one   groups of ladders is arranged in such a way as to   see moving relative to each other.   2. Evaluation aid according to claim 1, characterized in that the scales for total cholesterol and LDL cholesterol are gathered in one scale.   3. Evaluation assistant according to one of the   1 and 2, characterized in that the groups   The scales are arranged in two circular discs   different diameters connected to each other and   rotatable relative to each other.   4. Evaluation assistant according to one of the   1 to 3, characterized in that the scales   they are arranged in segments of a circle.   5. Evaluation assistant according to one of the   1 and 2, characterized in that the groups   scales are arranged on two rectangular indicating devices that can move one compared to each other.   6. Evaluation assistant according to one of the   Claims 1 to 5, characterized in that the scale   ticks for triglycerides represents the   fifth of the other parameters.