FR2470767B1 - - Google Patents

Info

Publication number
FR2470767B1
FR2470767B1 FR7930046A FR7930046A FR2470767B1 FR 2470767 B1 FR2470767 B1 FR 2470767B1 FR 7930046 A FR7930046 A FR 7930046A FR 7930046 A FR7930046 A FR 7930046A FR 2470767 B1 FR2470767 B1 FR 2470767B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7930046A
Other languages
French (fr)
Other versions
FR2470767A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Priority to FR7930046A priority Critical patent/FR2470767A1/fr
Priority to FR8016875A priority patent/FR2487829A2/fr
Priority to US06/212,607 priority patent/US4404206A/en
Priority to EP80401728A priority patent/EP0031741A1/fr
Priority to ES497517A priority patent/ES497517A0/es
Priority to JP17195780A priority patent/JPS5692270A/ja
Priority to AU65123/80A priority patent/AU539414B2/en
Priority to CA000366326A priority patent/CA1209985A/fr
Publication of FR2470767A1 publication Critical patent/FR2470767A1/fr
Priority to US06/308,234 priority patent/US4508729A/en
Application granted granted Critical
Publication of FR2470767B1 publication Critical patent/FR2470767B1/fr
Priority to US06/420,005 priority patent/US4565819A/en
Priority to US06/659,276 priority patent/US4616031A/en
Priority to US06/659,275 priority patent/US4616029A/en
Priority to US06/659,274 priority patent/US4644008A/en
Priority to US06/679,320 priority patent/US4616030A/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR7930046A 1979-12-07 1979-12-07 Nouveaux iminoacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzymes Granted FR2470767A1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR7930046A FR2470767A1 (fr) 1979-12-07 1979-12-07 Nouveaux iminoacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzymes
FR8016875A FR2487829A2 (fr) 1979-12-07 1980-07-31 Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
EP80401728A EP0031741A1 (fr) 1979-12-07 1980-12-03 Nouveaux iminoacides substitués, leurs procédés de préparation et leur emploi comme inhibiteurs d'enzymes
US06/212,607 US4404206A (en) 1979-12-07 1980-12-03 Substituted iminoacid derivatives, process for preparing them and their use as enzyme inhibitors
AU65123/80A AU539414B2 (en) 1979-12-07 1980-12-05 2-carboxylic azabicydoalkanes
JP17195780A JPS5692270A (en) 1979-12-07 1980-12-05 Novel bicyclic iminooacids* their manufacture and medicine containing them
ES497517A ES497517A0 (es) 1979-12-07 1980-12-05 Procedimiento de preparacion de nuevos iminoacidos y de sus derivados.
CA000366326A CA1209985A (fr) 1979-12-07 1980-12-08 Procede de preparation de nouveaux imino acides substitues
US06/308,234 US4508729A (en) 1979-12-07 1981-10-02 Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
US06/420,005 US4565819A (en) 1979-12-07 1982-09-20 Substituted imino diacids, their preparation and pharmaceutical compositions which contain them
US06/659,276 US4616031A (en) 1979-12-07 1984-10-10 Perhydroindole-2-carboxylic acids as antihypertensives
US06/659,274 US4644008A (en) 1979-12-07 1984-10-10 Perhydroindole-2-carboxylic acids as antihypertensives
US06/659,275 US4616029A (en) 1979-12-07 1984-10-10 Perhydromdole-2-carboxylic acids as antihypertensives
US06/679,320 US4616030A (en) 1979-12-07 1984-12-06 Perhydroindole-2-carboxylic acids as antihypertensives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7930046A FR2470767A1 (fr) 1979-12-07 1979-12-07 Nouveaux iminoacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzymes

Publications (2)

Publication Number Publication Date
FR2470767A1 FR2470767A1 (fr) 1981-06-12
FR2470767B1 true FR2470767B1 (no) 1982-04-30

Family

ID=9232491

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7930046A Granted FR2470767A1 (fr) 1979-12-07 1979-12-07 Nouveaux iminoacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzymes

Country Status (2)

Country Link
JP (1) JPS5692270A (no)
FR (1) FR2470767A1 (no)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350704A (en) 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4350633A (en) 1980-07-01 1982-09-21 American Home Products Corporation N-(2-Substituted-1-oxoalkyl)-2,3-dihydro-1H-indole-2-carboxylic acid derivatives

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2048863B (en) * 1979-05-16 1983-06-15 Morton Norwich Products Inc Tetrahydroisoquinoline-3-carboxylic acids
US4460775A (en) * 1979-08-09 1984-07-17 Norwich Eaton Pharmaceuticals, Inc. 2-(3-Mercapto-1-oxopropyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid derivatives
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
EP0278530A3 (de) * 1980-08-30 1989-08-02 Hoechst Aktiengesellschaft Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung
US4479963A (en) * 1981-02-17 1984-10-30 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4665087A (en) * 1982-02-22 1987-05-12 Ciba-Geigy Corporation 1-(carbamyl, thiocarbamyl, and iminocarbamyl)-indoline derivatives
AU2013202978B2 (en) * 2012-01-25 2016-05-19 Novartis Ag Heterocyclic compounds and methods for their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1524481A (en) * 1976-01-07 1978-09-13 Farmaceutici Italia Tetrahydo - imidazopyridine derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350633A (en) 1980-07-01 1982-09-21 American Home Products Corporation N-(2-Substituted-1-oxoalkyl)-2,3-dihydro-1H-indole-2-carboxylic acid derivatives
US4350704A (en) 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids

Also Published As

Publication number Publication date
JPH0127061B2 (no) 1989-05-26
FR2470767A1 (fr) 1981-06-12
JPS5692270A (en) 1981-07-25

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Legal Events

Date Code Title Description
ST Notification of lapse