FR2463765B1 - - Google Patents

Info

Publication number
FR2463765B1
FR2463765B1 FR7920907A FR7920907A FR2463765B1 FR 2463765 B1 FR2463765 B1 FR 2463765B1 FR 7920907 A FR7920907 A FR 7920907A FR 7920907 A FR7920907 A FR 7920907A FR 2463765 B1 FR2463765 B1 FR 2463765B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7920907A
Other languages
French (fr)
Other versions
FR2463765A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CM Industries SA
Clin Midy
Original Assignee
CM Industries SA
Clin Midy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CM Industries SA, Clin Midy filed Critical CM Industries SA
Priority to FR7920907A priority Critical patent/FR2463765A1/fr
Priority to EP80401180A priority patent/EP0025727B1/fr
Priority to JP11045680A priority patent/JPS5699413A/ja
Priority to DE8080401180T priority patent/DE3067264D1/de
Priority to CA000359075A priority patent/CA1161849A/en
Priority to US06/178,550 priority patent/US4404217A/en
Publication of FR2463765A1 publication Critical patent/FR2463765A1/fr
Application granted granted Critical
Publication of FR2463765B1 publication Critical patent/FR2463765B1/fr
Priority to CA000426344A priority patent/CA1164464A/en
Priority to US06/530,699 priority patent/US4510315A/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7920907A 1979-08-17 1979-08-17 Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire Granted FR2463765A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR7920907A FR2463765A1 (fr) 1979-08-17 1979-08-17 Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
JP11045680A JPS5699413A (en) 1979-08-17 1980-08-13 Cardiovascularly active indole derivative
DE8080401180T DE3067264D1 (en) 1979-08-17 1980-08-13 Indole derivatives, process for their preparation and medicaments containing them
EP80401180A EP0025727B1 (fr) 1979-08-17 1980-08-13 Dérivés de l'indole, procédé pour leur préparation et médicaments les contenant
CA000359075A CA1161849A (en) 1979-08-17 1980-08-15 Derivatives of indole active on the cardiovascular system
US06/178,550 US4404217A (en) 1979-08-17 1980-08-15 3-Indolyl alkylene amino propanols and cardiovascular compositions thereof
CA000426344A CA1164464A (en) 1979-08-17 1983-04-20 Derivatives of indole active on the cardiovascular system
US06/530,699 US4510315A (en) 1979-08-17 1983-09-09 4[3-(1,1-Dimethyl-2-3(3-indolyl)ethylamino)-2-hydroxypropoxy]indole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7920907A FR2463765A1 (fr) 1979-08-17 1979-08-17 Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire

Publications (2)

Publication Number Publication Date
FR2463765A1 FR2463765A1 (fr) 1981-02-27
FR2463765B1 true FR2463765B1 (en:Method) 1983-01-21

Family

ID=9228923

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7920907A Granted FR2463765A1 (fr) 1979-08-17 1979-08-17 Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire

Country Status (6)

Country Link
US (2) US4404217A (en:Method)
EP (1) EP0025727B1 (en:Method)
JP (1) JPS5699413A (en:Method)
CA (1) CA1161849A (en:Method)
DE (1) DE3067264D1 (en:Method)
FR (1) FR2463765A1 (en:Method)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (de) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
FR2543952B1 (fr) * 1982-09-03 1986-02-21 Bristol Myers Co Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2589863B1 (fr) * 1985-11-12 1988-07-29 Sanofi Sa Derives d'hydroxy-4 indole, leur procede de preparation et leur utilisation
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
FR2638747B1 (fr) * 1988-11-08 1993-12-24 Synthelabo Derives de phenyloxypropanolamines, leur preparation et leur application en therapeutique
US5189179A (en) * 1990-08-29 1993-02-23 Merrell Dow Pharmaceuticals Inc. Serotonin 5ht1a agonists
US5436264A (en) * 1993-08-19 1995-07-25 Syntex (U.S.A.) Inc. N-aryloxyalkyl tryptamine α1 -adrenergic receptor antagonists
AU3386199A (en) * 1998-04-08 1999-10-25 American Home Products Corporation N-aryloxyethyl-indoly-alkylamines for the treatment of depression (5-ht1a receptor active agents)
US6121307A (en) * 1998-04-08 2000-09-19 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
DE10306941A1 (de) * 2003-02-18 2004-08-26 Merck Patent Gmbh Benzofuranoxyethylamine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH585199A5 (en:Method) * 1972-09-15 1977-02-28 Siegfried Ag
US4234595A (en) * 1977-07-13 1980-11-18 Mead Johnson & Company 3-Indolyl-tertiary butylaminopropanols
CA1116598A (en) * 1977-07-13 1982-01-19 William T. Comer 3-indolyl-tertiary butylaminopropanols

Also Published As

Publication number Publication date
EP0025727B1 (fr) 1984-03-28
CA1161849A (en) 1984-02-07
JPS5699413A (en) 1981-08-10
US4510315A (en) 1985-04-09
DE3067264D1 (en) 1984-05-03
US4404217A (en) 1983-09-13
FR2463765A1 (fr) 1981-02-27
EP0025727A1 (fr) 1981-03-25

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse