FR2457301A1 - N-ACYL AND N-ALKYL DERIVATIVES OF FORTIMICIN B, THEIR MANUFACTURING PROCESS AND THEIR USE AS ANTIBIOTICS - Google Patents

N-ACYL AND N-ALKYL DERIVATIVES OF FORTIMICIN B, THEIR MANUFACTURING PROCESS AND THEIR USE AS ANTIBIOTICS

Info

Publication number
FR2457301A1
FR2457301A1 FR7913167A FR7913167A FR2457301A1 FR 2457301 A1 FR2457301 A1 FR 2457301A1 FR 7913167 A FR7913167 A FR 7913167A FR 7913167 A FR7913167 A FR 7913167A FR 2457301 A1 FR2457301 A1 FR 2457301A1
Authority
FR
France
Prior art keywords
fortimicin
manufacturing process
antibiotics
acyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7913167A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to FR7913167A priority Critical patent/FR2457301A1/en
Publication of FR2457301A1 publication Critical patent/FR2457301A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

DERIVES N-ACYLES ET N-ALKYLES DE LA FORTIMICINE B, LEUR PROCEDE DE FABRICATION ET LEUR UTILISATION COMME ANTIBIOTIQUES. LA PRESENTE INVENTION CONCERNE LES DERIVES DE FORTIMICINES B REPRESENTES PAR LA FORMULE: (CF DESSIN DANS BOPI) DANS LAQUELLE R ET R REPRESENTENT DIVERS GROUPEMENTS ALKYLE ET ACYLE ET LES SELS SUBSTITUES SUR LES ATOMES D'AZOTE EN POSITION 2 ETOU 4 INDIQUES DANS LE MEMOIRE DE CES COMPOSES ACCEPTABLES PHARMACEUTIQUES AINSI QUE LES COMPOSITIONS PHARMACEUTIQUES CONTENANT CES COMPOSES ET LE PROCEDE DE FABRICATION DE CES COMPOSES. UTILISATION DE CES COMPOSES COMME ANTIBIOTIQUES CONTRE LES BACTERIES GRAM-POSITIVES ET GRAM-NEGATIVES.N-ACYL AND N-ALKYL DERIVATIVES OF FORTIMICIN B, THEIR MANUFACTURING PROCESS AND THEIR USE AS ANTIBIOTICS. THE PRESENT INVENTION CONCERNS FORTIMICIN B DERIVATIVES REPRESENTED BY THE FORMULA: (CF DRAWING IN BOPI) IN WHICH R AND R REPRESENT VARIOUS ALKYL AND ACYL GROUPS AND THE SUBSTITUTED SALTS ON THE NITROGEN ATOMS IN POSITION 2 AND OR 4 INDICATED IN THE MEMORY OF THESE ACCEPTABLE PHARMACEUTICAL COMPOUNDS AS WELL AS PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND THE MANUFACTURING PROCESS OF THESE COMPOUNDS. USE OF THESE COMPOUNDS AS ANTIBIOTICS AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA.

FR7913167A 1979-05-23 1979-05-23 N-ACYL AND N-ALKYL DERIVATIVES OF FORTIMICIN B, THEIR MANUFACTURING PROCESS AND THEIR USE AS ANTIBIOTICS Pending FR2457301A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7913167A FR2457301A1 (en) 1979-05-23 1979-05-23 N-ACYL AND N-ALKYL DERIVATIVES OF FORTIMICIN B, THEIR MANUFACTURING PROCESS AND THEIR USE AS ANTIBIOTICS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7913167A FR2457301A1 (en) 1979-05-23 1979-05-23 N-ACYL AND N-ALKYL DERIVATIVES OF FORTIMICIN B, THEIR MANUFACTURING PROCESS AND THEIR USE AS ANTIBIOTICS

Publications (1)

Publication Number Publication Date
FR2457301A1 true FR2457301A1 (en) 1980-12-19

Family

ID=9225792

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7913167A Pending FR2457301A1 (en) 1979-05-23 1979-05-23 N-ACYL AND N-ALKYL DERIVATIVES OF FORTIMICIN B, THEIR MANUFACTURING PROCESS AND THEIR USE AS ANTIBIOTICS

Country Status (1)

Country Link
FR (1) FR2457301A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5446747A (en) * 1977-09-21 1979-04-12 Kyowa Hakko Kogyo Co Ltd Fortimicin ko and its preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5446747A (en) * 1977-09-21 1979-04-12 Kyowa Hakko Kogyo Co Ltd Fortimicin ko and its preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1979 *

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