FR2449674A1 - Procede pour la preparation de l'acide o.(2,6-dichloroanilino)-phenylacetique - Google Patents

Procede pour la preparation de l'acide o.(2,6-dichloroanilino)-phenylacetique

Info

Publication number
FR2449674A1
FR2449674A1 FR7914941A FR7914941A FR2449674A1 FR 2449674 A1 FR2449674 A1 FR 2449674A1 FR 7914941 A FR7914941 A FR 7914941A FR 7914941 A FR7914941 A FR 7914941A FR 2449674 A1 FR2449674 A1 FR 2449674A1
Authority
FR
France
Prior art keywords
chloro
reduced
reaction
isatin
iodo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7914941A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcar Srl
Original Assignee
Alcar Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcar Srl filed Critical Alcar Srl
Publication of FR2449674A1 publication Critical patent/FR2449674A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)

Abstract

CET ACIDE EST REPRESENTE PAR LA FORMULE I CI-APRES. POUR LE PREPARER, ON FAIT REAGIR L'ISATINE AVEC LE 2,6-DICHLORO-IODO-BENZENE SUIVANT L'EQUATION II CI-APRES, PUIS ON PREPARE LA TOSYL-HYDRAZONE DE LA 2,6-DICHLOROPHENYL-INDOLO-2,3-DIONE AINSI OBTENUE (EQUATION III CI-APRES) ET ON REDUIT LA TOSYL-HYDRAZONE DE LA 2,6-DICHLOROPHENYL-INDOLO-2,3-DIONE AVEC NABH EN SOLUTION ACIDE A 60-70C (EQUATION IV). L'ACIDE O.(2,6-DICHLOROANILINO)-PHENYLACETIQUE EST UN PRODUIT CONNU DEPUIS QUELQUES ANNEES ENTANT QU'ANTI-INFLAMMATOIRE, ANALGESIQUE ET ANTIPYRETIQUE. (CF DESSIN DANS BOPI)
FR7914941A 1979-02-23 1979-06-12 Procede pour la preparation de l'acide o.(2,6-dichloroanilino)-phenylacetique Withdrawn FR2449674A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20499/79A IT1112024B (it) 1979-02-23 1979-02-23 Processo per la preparazione dell'acido o.(2,6-dicloroanilino)-fenilacetico

Publications (1)

Publication Number Publication Date
FR2449674A1 true FR2449674A1 (fr) 1980-09-19

Family

ID=11167852

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7914941A Withdrawn FR2449674A1 (fr) 1979-02-23 1979-06-12 Procede pour la preparation de l'acide o.(2,6-dichloroanilino)-phenylacetique

Country Status (2)

Country Link
FR (1) FR2449674A1 (fr)
IT (1) IT1112024B (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1595382A (fr) * 1967-12-20 1970-06-08

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1595382A (fr) * 1967-12-20 1970-06-08

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/66 *

Also Published As

Publication number Publication date
IT7920499A0 (it) 1979-02-23
IT1112024B (it) 1986-01-13

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Legal Events

Date Code Title Description
RE Withdrawal of published application