FR2447931A1 - NOVEL ANTIBIOTIC NAME AX-127B-1, EFFECTIVE IN PARTICULAR AGAINST POSITIVE AND NEGATIVE-GRAM ORGANISMS, AND ITS MANUFACTURING PROCESS VIA A MICROMONOSPORA GENUS - Google Patents
NOVEL ANTIBIOTIC NAME AX-127B-1, EFFECTIVE IN PARTICULAR AGAINST POSITIVE AND NEGATIVE-GRAM ORGANISMS, AND ITS MANUFACTURING PROCESS VIA A MICROMONOSPORA GENUSInfo
- Publication number
- FR2447931A1 FR2447931A1 FR8002115A FR8002115A FR2447931A1 FR 2447931 A1 FR2447931 A1 FR 2447931A1 FR 8002115 A FR8002115 A FR 8002115A FR 8002115 A FR8002115 A FR 8002115A FR 2447931 A1 FR2447931 A1 FR 2447931A1
- Authority
- FR
- France
- Prior art keywords
- nr4porosa
- micromporosa
- negative
- effective
- manufacturing process
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/29—Micromonospora
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
L'ANTIBIOTIQUE AX-127B-1 EST UN COMPOSE DU TYPE AMINO-GLUCOSIDE ET PRESENTE LES PROPRIETES SUIVANTES: A.SOLUBLE DANS L'EAU, TRES LEGEREMENT SOLUBLE DANS LE METHANOL ET ESSENTIELLEMENT INSOLUBLE DANS LES AUTRES SOLVANTS ORGANIQUES COURANTS; B.POIDS MOLECULAIRE 460; C.FORMULE EMPIRIQUE CHNO; D.SPECTRE IR REPRESENTE PAR LA FIGURE1; E.SPECTRE DE MASSE DONNANT POUR L'ION PARENT UNE VALEUR DE 460,2998; F.SPECTRE DE RESONANCE MAGNETIQUE DU CARBONE PRESENTANT LES BANDES SUIVANTES (D, PPM):23,141,448,972,596,2 29,143,456,073,598,5 34,444,257,881,4150,938,546,860,482,6175,3 IL EST PRODUIT PAR UN MICRORGANISME CHOISI PARMI MICROMONOSPORA PILOSOSPORA NRRL11415, MICROMONOSPORA PILOSOSPORA NRRL11416 ET MICROMONOSPORA PILOSOSPORA NRRL11417 ET LEURS MUTANTS.ANTIBIOTIC AX-127B-1 IS AN AMINO-GLUCOSIDE TYPE COMPOUND AND HAS THE FOLLOWING PROPERTIES: A. WATER-SOLUBLE, VERY SLIGHTLY SOLUBLE IN METHANOL AND ESSENTIALLY INSOLUBLE IN OTHER COMMON ORGANIC SOLVENTS; B. MOLECULAR WEIGHT 460; C. EMPIRICAL FORMULA CHNO; D. IR SPECTRUM REPRESENTED BY FIGURE 1; E. MASS SPECTRUM GIVING FOR THE PARENT ION A VALUE OF 460.2998; F. SPECTRUM OF MAGNETIC RESONANCE OF CARBON PRESENTING THE FOLLOWING BANDS (D, PPM): 23,141,448,972,596,2 29,143,456,073,598,5 34,444,257,881,4150,938,546,860,482,6175,3 IT IS PRODUCED BY A MICRORGANISM P11POROSA MICROMPOROSA MICROMPOROSA 11POROSA P11POROSA MICROMPOROSA NR4POROSA Nr4POROSA11POROSA Nr4POROSA Nr4POROSA Nr4POROSA Nr4POROSA Nr4POROSA Nr. PILOSOSPORA NRRL11417 AND THEIR MUTANTS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US837879A | 1979-02-01 | 1979-02-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2447931A1 true FR2447931A1 (en) | 1980-08-29 |
FR2447931B1 FR2447931B1 (en) | 1983-04-01 |
Family
ID=21731303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8002115A Granted FR2447931A1 (en) | 1979-02-01 | 1980-01-31 | NOVEL ANTIBIOTIC NAME AX-127B-1, EFFECTIVE IN PARTICULAR AGAINST POSITIVE AND NEGATIVE-GRAM ORGANISMS, AND ITS MANUFACTURING PROCESS VIA A MICROMONOSPORA GENUS |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS55104298A (en) |
AR (1) | AR221524A1 (en) |
AU (1) | AU5488280A (en) |
BE (1) | BE881476A (en) |
DE (1) | DE3003497A1 (en) |
ES (1) | ES8103165A1 (en) |
FR (1) | FR2447931A1 (en) |
GB (1) | GB2042501B (en) |
IT (1) | IT1149288B (en) |
SE (1) | SE8000786L (en) |
ZA (1) | ZA80373B (en) |
-
1980
- 1980-01-22 ZA ZA00800373A patent/ZA80373B/en unknown
- 1980-01-23 AU AU54882/80A patent/AU5488280A/en not_active Abandoned
- 1980-01-28 AR AR279764A patent/AR221524A1/en active
- 1980-01-28 GB GB8002742A patent/GB2042501B/en not_active Expired
- 1980-01-31 FR FR8002115A patent/FR2447931A1/en active Granted
- 1980-01-31 BE BE0/199210A patent/BE881476A/en not_active IP Right Cessation
- 1980-01-31 IT IT19606/80A patent/IT1149288B/en active
- 1980-01-31 DE DE19803003497 patent/DE3003497A1/en not_active Withdrawn
- 1980-01-31 SE SE8000786A patent/SE8000786L/en not_active Application Discontinuation
- 1980-02-01 JP JP1011680A patent/JPS55104298A/en active Pending
- 1980-02-01 ES ES488208A patent/ES8103165A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE3003497A1 (en) | 1980-08-14 |
AU5488280A (en) | 1980-08-07 |
JPS55104298A (en) | 1980-08-09 |
AR221524A1 (en) | 1981-02-13 |
FR2447931B1 (en) | 1983-04-01 |
ES488208A0 (en) | 1981-02-16 |
GB2042501B (en) | 1983-10-19 |
IT1149288B (en) | 1986-12-03 |
GB2042501A (en) | 1980-09-24 |
SE8000786L (en) | 1980-08-02 |
ZA80373B (en) | 1981-01-28 |
IT8019606A0 (en) | 1980-01-31 |
ES8103165A1 (en) | 1981-02-16 |
BE881476A (en) | 1980-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |