FR2439779A2 - Hypotensive hydroxy cyclopentane carboxylic acid lactone(s) - Google Patents

Hypotensive hydroxy cyclopentane carboxylic acid lactone(s)

Info

Publication number
FR2439779A2
FR2439779A2 FR7830054A FR7830054A FR2439779A2 FR 2439779 A2 FR2439779 A2 FR 2439779A2 FR 7830054 A FR7830054 A FR 7830054A FR 7830054 A FR7830054 A FR 7830054A FR 2439779 A2 FR2439779 A2 FR 2439779A2
Authority
FR
France
Prior art keywords
carboxylic acid
acid lactone
cyclopentane carboxylic
hypotensive
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7830054A
Other languages
French (fr)
Other versions
FR2439779B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7608004A external-priority patent/FR2344285A1/en
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7830054A priority Critical patent/FR2439779A2/en
Priority to US06/036,877 priority patent/US4221809A/en
Priority to US06/131,053 priority patent/US4279919A/en
Publication of FR2439779A2 publication Critical patent/FR2439779A2/en
Application granted granted Critical
Publication of FR2439779B2 publication Critical patent/FR2439779B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/32—Unsaturated compounds containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Abstract

The following cyclopentanol derivatives are new. (IA) (1RS, 2SR, 5RS, 3'RS) (1'E) 2,3'dihydroxy 5-(1'-octenyl) cyclopentane carboxylic acid lactone. (IB) (1RS, 2SR, 5RS, 3'SR) (1'E) 2-hydroxy 5-(3'-tetrahydropyranyloxy 1'-nonenyl) cyclopentane carboxylic acid lactone. (IC) (1RS, 2SR, 5RS, 3'SR) (1'E) 2,3-dihydroxy 5-(1'-nonenyl) cyclopentane carboxylic acid lactone, and (ID) (1RS, 2SR, 5RS, 3'SR) (1'E) 2,3-dihydroxy 5-(1'-hexenyl)cyclopentane carboxylic acid lactone.The cpds. are hypotensives. The parent patent covered (IA-C) in general terms and cpds. closely related to
FR7830054A 1976-03-19 1978-10-23 Hypotensive hydroxy cyclopentane carboxylic acid lactone(s) Granted FR2439779A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR7830054A FR2439779A2 (en) 1976-03-19 1978-10-23 Hypotensive hydroxy cyclopentane carboxylic acid lactone(s)
US06/036,877 US4221809A (en) 1978-10-23 1979-05-08 β-Lactones of 2-hydroxy-cyclopentanecarboxylic acid
US06/131,053 US4279919A (en) 1976-03-19 1980-03-17 Novel lactones of cyclopentanols

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7608004A FR2344285A1 (en) 1976-03-19 1976-03-19 NEW LACTONS DERIVED FROM CYCLOPENTANOL, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
FR7830054A FR2439779A2 (en) 1976-03-19 1978-10-23 Hypotensive hydroxy cyclopentane carboxylic acid lactone(s)

Publications (2)

Publication Number Publication Date
FR2439779A2 true FR2439779A2 (en) 1980-05-23
FR2439779B2 FR2439779B2 (en) 1981-05-22

Family

ID=26219362

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7830054A Granted FR2439779A2 (en) 1976-03-19 1978-10-23 Hypotensive hydroxy cyclopentane carboxylic acid lactone(s)

Country Status (1)

Country Link
FR (1) FR2439779A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2344285A1 (en) * 1976-03-19 1977-10-14 Roussel Uclaf NEW LACTONS DERIVED FROM CYCLOPENTANOL, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2344285A1 (en) * 1976-03-19 1977-10-14 Roussel Uclaf NEW LACTONS DERIVED FROM CYCLOPENTANOL, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Also Published As

Publication number Publication date
FR2439779B2 (en) 1981-05-22

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