FR2424912A1 - IMIDAZOLE DERIVATIVES USED IN PARTICULAR FOR THE TREATMENT OF HYPERTENSION - Google Patents

IMIDAZOLE DERIVATIVES USED IN PARTICULAR FOR THE TREATMENT OF HYPERTENSION

Info

Publication number
FR2424912A1
FR2424912A1 FR7910988A FR7910988A FR2424912A1 FR 2424912 A1 FR2424912 A1 FR 2424912A1 FR 7910988 A FR7910988 A FR 7910988A FR 7910988 A FR7910988 A FR 7910988A FR 2424912 A1 FR2424912 A1 FR 2424912A1
Authority
FR
France
Prior art keywords
hypertension
treatment
imidazole derivatives
derivatives used
imidazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7910988A
Other languages
French (fr)
Other versions
FR2424912B1 (en
Inventor
Tadao Tanouchi
Masanori Kawamura
Ikuo Kajiwara
Yoichi Iguchi
Masaki Hayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP53052266A external-priority patent/JPS6050190B2/en
Priority claimed from JP53068892A external-priority patent/JPS6054307B2/en
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of FR2424912A1 publication Critical patent/FR2424912A1/en
Application granted granted Critical
Publication of FR2424912B1 publication Critical patent/FR2424912B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Abstract

L'INVENTION A POUR OBJET DES DERIVES DE L'IMIDAZOLE. CES DERIVES DE L'IMIDAZOLE REPONDENT A LA FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE R REPRESENTE UN ATOME D'HYDROGENE OU UN GROUPE ALKYLE LINEAIRE OU RAMIFIE ENTHE SUBJECT OF THE INVENTION IS DERIVATIVES OF IMIDAZOLE. THESE DERIVATIVES OF IMIDAZOLE MEET THE GENERAL FORMULA: (CF DRAWING IN BOPI) IN WHICH R REPRESES A HYDROGEN ATOM OR A LINEAR OR BRANCHED ALKYL GROUP

FR7910988A 1978-05-02 1979-05-02 IMIDAZOLE DERIVATIVES USED IN PARTICULAR FOR THE TREATMENT OF HYPERTENSION Granted FR2424912A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP53052266A JPS6050190B2 (en) 1978-05-02 1978-05-02 Imidazole derivative
JP53068892A JPS6054307B2 (en) 1978-06-09 1978-06-09 Imidazole derivative

Publications (2)

Publication Number Publication Date
FR2424912A1 true FR2424912A1 (en) 1979-11-30
FR2424912B1 FR2424912B1 (en) 1983-05-20

Family

ID=26392871

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7910988A Granted FR2424912A1 (en) 1978-05-02 1979-05-02 IMIDAZOLE DERIVATIVES USED IN PARTICULAR FOR THE TREATMENT OF HYPERTENSION

Country Status (5)

Country Link
CH (1) CH640516A5 (en)
DE (1) DE2917456A1 (en)
FR (1) FR2424912A1 (en)
GB (1) GB2024807B (en)
IT (1) IT1162310B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0107618A1 (en) * 1982-09-30 1984-05-02 Ciba-Geigy Ag N-substituted-2-(1-imidazolyl)-indoles
US4539410A (en) * 1982-09-30 1985-09-03 Ciba-Geigy Corporation N-Substituted-2-(1-imidazolyl)indoles

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5756464A (en) * 1980-09-22 1982-04-05 Ono Pharmaceut Co Ltd Imidazole derivative ahd inhibitor for biosyntesis of thromboxane a2
JPS5770872A (en) * 1980-10-22 1982-05-01 Ono Pharmaceut Co Ltd Imidazole derivative and biosynthetic inhibitor against thromboxana a2 containg the same
CS229934B2 (en) * 1981-07-07 1984-07-16 Pfizer Production method subst.indolylacryte acid derivative

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941434A (en) * 1972-08-11 1974-04-18

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1486817A (en) * 1965-07-22 1967-06-30 Basf Ag Insecticides
GB1535777A (en) * 1975-08-26 1978-12-13 Ici Ltd Imidazole and 1,2,4-triazole compounds and their use as pesticides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941434A (en) * 1972-08-11 1974-04-18

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1975 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0107618A1 (en) * 1982-09-30 1984-05-02 Ciba-Geigy Ag N-substituted-2-(1-imidazolyl)-indoles
US4539410A (en) * 1982-09-30 1985-09-03 Ciba-Geigy Corporation N-Substituted-2-(1-imidazolyl)indoles

Also Published As

Publication number Publication date
DE2917456A1 (en) 1980-01-10
GB2024807A (en) 1980-01-16
FR2424912B1 (en) 1983-05-20
IT1162310B (en) 1987-03-25
GB2024807B (en) 1982-07-28
CH640516A5 (en) 1984-01-13
DE2917456C2 (en) 1991-01-10
IT7948874A0 (en) 1979-04-27

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Legal Events

Date Code Title Description
ST Notification of lapse