FR2421896A1 - Procede d'isolation a partir de la plante zoapatle de deux composes biologiquement actifs derives du methyl-2 hydroxy-3 beta-hydroxyethylidene-6 oxepanne - Google Patents

Procede d'isolation a partir de la plante zoapatle de deux composes biologiquement actifs derives du methyl-2 hydroxy-3 beta-hydroxyethylidene-6 oxepanne

Info

Publication number
FR2421896A1
FR2421896A1 FR7822513A FR7822513A FR2421896A1 FR 2421896 A1 FR2421896 A1 FR 2421896A1 FR 7822513 A FR7822513 A FR 7822513A FR 7822513 A FR7822513 A FR 7822513A FR 2421896 A1 FR2421896 A1 FR 2421896A1
Authority
FR
France
Prior art keywords
biologically active
oxepanne
hydroxyethylidene
beta
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7822513A
Other languages
English (en)
Other versions
FR2421896B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Publication of FR2421896A1 publication Critical patent/FR2421896A1/fr
Application granted granted Critical
Publication of FR2421896B1 publication Critical patent/FR2421896B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/04—Seven-membered rings not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

L'invention concerne un procédé d'isolation de substances d'évacuation utérine à partir de la plante zoapatle. Ce procédé comprend le traitement de résidus contenant des substances biologiquement actives de formules I-a et I-b suivantes :
FR7822513A 1977-08-08 1978-07-28 Procede d'isolation a partir de la plante zoapatle de deux composes biologiquement actifs derives du methyl-2 hydroxy-3 beta-hydroxyethylidene-6 oxepanne Granted FR2421896A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/822,479 US4112079A (en) 1977-08-08 1977-08-08 Isolation of uteroevacuant substances from plant extracts

Publications (2)

Publication Number Publication Date
FR2421896A1 true FR2421896A1 (fr) 1979-11-02
FR2421896B1 FR2421896B1 (fr) 1982-12-31

Family

ID=25236149

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7822513A Granted FR2421896A1 (fr) 1977-08-08 1978-07-28 Procede d'isolation a partir de la plante zoapatle de deux composes biologiquement actifs derives du methyl-2 hydroxy-3 beta-hydroxyethylidene-6 oxepanne

Country Status (5)

Country Link
US (1) US4112079A (fr)
JP (1) JPS5449316A (fr)
CA (1) CA1112650A (fr)
FR (1) FR2421896A1 (fr)
GB (1) GB2014559B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4176188A (en) * 1976-11-18 1979-11-27 Ortho Pharmaceutical Corp. Utero-evacuants
US4256644A (en) * 1978-12-18 1981-03-17 Ortho Pharmaceutical Corporation Chemical intermediates in the preparation of oxepane compounds
US4491593A (en) * 1983-01-27 1985-01-01 Gallegos Alfredo J Compositions and methods for fertility control

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2395777A1 (fr) * 1977-06-30 1979-01-26 Snam Progetti Compositions chimiques a base de trihalogenures de titane, procede pour leur preparation et leur application
FR2395755A1 (fr) * 1977-06-29 1979-01-26 Ortho Pharma Corp Isolement de substances biologiquement actives, utiles notamment pour l'evacuation de l'uterus, a partir d'extraits de la plante zoapatle

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4006227A (en) * 1973-11-15 1977-02-01 Gallegos Alfred J Compositions and methods for fertility control
US3996132A (en) * 1974-07-18 1976-12-07 Ortho Pharmaceutical Corporation Purification of utero-evacuant extracts from plant substances
US3986952A (en) * 1975-11-17 1976-10-19 Ortho Pharmaceutical Corporation Isolation of utero-evacuant substances from plant extracts
US4060604A (en) * 1976-09-27 1977-11-29 Ortho Pharmaceutical Corporation Isolation of utero-evacuant substances from plant extracts
US4046882A (en) * 1976-11-18 1977-09-06 Ortho Pharmaceutical Corporation Isolation of utero-evacuant substances from plant extracts

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2395755A1 (fr) * 1977-06-29 1979-01-26 Ortho Pharma Corp Isolement de substances biologiquement actives, utiles notamment pour l'evacuation de l'uterus, a partir d'extraits de la plante zoapatle
FR2395777A1 (fr) * 1977-06-30 1979-01-26 Snam Progetti Compositions chimiques a base de trihalogenures de titane, procede pour leur preparation et leur application

Also Published As

Publication number Publication date
US4112079A (en) 1978-09-05
GB2014559B (en) 1982-03-10
CA1112650A (fr) 1981-11-17
GB2014559A (en) 1979-08-30
FR2421896B1 (fr) 1982-12-31
JPS5449316A (en) 1979-04-18

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Legal Events

Date Code Title Description
ST Notification of lapse