FR2421178A1 - CONJUGATE OF AN ACYL-N-ACETYLMURAMYL-PEPTIDE DERIVATIVE AND AN ANTIGEN, ITS PREPARATION PROCESS AND ITS THERAPEUTIC APPLICATION - Google Patents

CONJUGATE OF AN ACYL-N-ACETYLMURAMYL-PEPTIDE DERIVATIVE AND AN ANTIGEN, ITS PREPARATION PROCESS AND ITS THERAPEUTIC APPLICATION

Info

Publication number
FR2421178A1
FR2421178A1 FR7908265A FR7908265A FR2421178A1 FR 2421178 A1 FR2421178 A1 FR 2421178A1 FR 7908265 A FR7908265 A FR 7908265A FR 7908265 A FR7908265 A FR 7908265A FR 2421178 A1 FR2421178 A1 FR 2421178A1
Authority
FR
France
Prior art keywords
acetylmuramyl
acyl
antigen
conjugate
peptide derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7908265A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2421178A1 publication Critical patent/FR2421178A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention a pour objet un produit conjugué d'un dérivé d'acyl-N-acétylmuramyl-peptide et d'un antigène qui répond à la formule :The subject of the invention is a conjugate product of an acyl-N-acetylmuramyl-peptide derivative and of an antigen which corresponds to the formula:

FR7908265A 1978-03-31 1979-04-02 CONJUGATE OF AN ACYL-N-ACETYLMURAMYL-PEPTIDE DERIVATIVE AND AN ANTIGEN, ITS PREPARATION PROCESS AND ITS THERAPEUTIC APPLICATION Withdrawn FR2421178A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3790178A JPS54130516A (en) 1978-03-31 1978-03-31 Acyllnnacetylmuramylpeptide derivativeeantigen combination

Publications (1)

Publication Number Publication Date
FR2421178A1 true FR2421178A1 (en) 1979-10-26

Family

ID=12510433

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7908265A Withdrawn FR2421178A1 (en) 1978-03-31 1979-04-02 CONJUGATE OF AN ACYL-N-ACETYLMURAMYL-PEPTIDE DERIVATIVE AND AN ANTIGEN, ITS PREPARATION PROCESS AND ITS THERAPEUTIC APPLICATION

Country Status (4)

Country Link
JP (1) JPS54130516A (en)
DE (1) DE2912865A1 (en)
FR (1) FR2421178A1 (en)
GB (1) GB2020665A (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0025842A2 (en) * 1979-07-31 1981-04-01 Fujisawa Pharmaceutical Co., Ltd. Peptides, process for their preparation, their pharmaceutical compositions and their intermediates
EP0027260A2 (en) * 1979-10-11 1981-04-22 Fujisawa Pharmaceutical Co., Ltd. Peptides, processes for their preparation and pharmaceutical compositions containing them
FR2477551A1 (en) * 1980-03-10 1981-09-11 Anvar NEW DERIVATIVES OF A-TREHALOSE AND MEDICAMENTS CONTAINING SAME
FR2482959A2 (en) * 1979-06-29 1981-11-27 Rhone Poulenc Ind Merrifield synthesis of immunostimulant and adjuvant tri:peptide(s) - produces fatty acid acrylated l-alanine d-glutamic acid 2-lysine or 2,6-di:amino-pimelamic acid cpds.
FR2482958A2 (en) * 1979-06-29 1981-11-27 Rhone Poulenc Ind Immunostimulant and adjuvant L-alanyl-D-glutamyl tri:peptide derivs. - in which the C-terminal aminoacid is l-lysine or di:amino-pimelic acid and which has a fatty acid n-acyl gp.
FR2546756A1 (en) * 1983-06-03 1984-12-07 Centre Nat Rech Scient NOVEL IMMUNOSTIMULATING DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS A MEDICINAL PRODUCT
EP0277755A1 (en) * 1987-01-30 1988-08-10 Kissei Pharmaceutical Co. Ltd. 4H-quinolizin-4-one compounds exhibiting therapeutic activities

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10610564B2 (en) 2015-02-26 2020-04-07 Stc.Unm IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
GB2579253A (en) * 2018-11-28 2020-06-17 Pedanius Therapeutics Ltd Antibacterial antisense agents

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1915970A1 (en) * 1968-03-29 1969-10-09 Anvar Process for the manufacture of products based on active protein substances
DE2450355A1 (en) * 1973-10-23 1975-05-28 Anvar ADJUVANCES FORMED FROM N-ACYL-MURAMIC ACID DERIVATIVES AND VACCINES CONTAINING THEM
EP0003833A2 (en) * 1978-02-24 1979-09-05 Ciba-Geigy Ag Antigen derivatives, process for their preparation, pharmaceutical compositions containing them

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1915970A1 (en) * 1968-03-29 1969-10-09 Anvar Process for the manufacture of products based on active protein substances
DE2450355A1 (en) * 1973-10-23 1975-05-28 Anvar ADJUVANCES FORMED FROM N-ACYL-MURAMIC ACID DERIVATIVES AND VACCINES CONTAINING THEM
EP0003833A2 (en) * 1978-02-24 1979-09-05 Ciba-Geigy Ag Antigen derivatives, process for their preparation, pharmaceutical compositions containing them

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2482959A2 (en) * 1979-06-29 1981-11-27 Rhone Poulenc Ind Merrifield synthesis of immunostimulant and adjuvant tri:peptide(s) - produces fatty acid acrylated l-alanine d-glutamic acid 2-lysine or 2,6-di:amino-pimelamic acid cpds.
FR2482958A2 (en) * 1979-06-29 1981-11-27 Rhone Poulenc Ind Immunostimulant and adjuvant L-alanyl-D-glutamyl tri:peptide derivs. - in which the C-terminal aminoacid is l-lysine or di:amino-pimelic acid and which has a fatty acid n-acyl gp.
EP0025842A2 (en) * 1979-07-31 1981-04-01 Fujisawa Pharmaceutical Co., Ltd. Peptides, process for their preparation, their pharmaceutical compositions and their intermediates
EP0025842A3 (en) * 1979-07-31 1982-02-10 Fujisawa Pharmaceutical Co. Ltd. Peptides, process for their preparation, their pharmaceutical compositions and their intermediates
EP0027260A2 (en) * 1979-10-11 1981-04-22 Fujisawa Pharmaceutical Co., Ltd. Peptides, processes for their preparation and pharmaceutical compositions containing them
EP0027260A3 (en) * 1979-10-11 1981-06-03 Fujisawa Pharmaceutical Co. Ltd. New peptides, processes for their preparation and pharmaceutical compositions containing them
FR2477551A1 (en) * 1980-03-10 1981-09-11 Anvar NEW DERIVATIVES OF A-TREHALOSE AND MEDICAMENTS CONTAINING SAME
WO1981002576A1 (en) * 1980-03-10 1981-09-17 Anvar New derivatives of 1'0alpha,0alpha'-trehalose and drugs containing them
FR2546756A1 (en) * 1983-06-03 1984-12-07 Centre Nat Rech Scient NOVEL IMMUNOSTIMULATING DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS A MEDICINAL PRODUCT
EP0128097A1 (en) * 1983-06-03 1984-12-12 Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) Immunostiumulating derivatives, their preparation and their use as medicines
EP0277755A1 (en) * 1987-01-30 1988-08-10 Kissei Pharmaceutical Co. Ltd. 4H-quinolizin-4-one compounds exhibiting therapeutic activities

Also Published As

Publication number Publication date
GB2020665A (en) 1979-11-21
JPS54130516A (en) 1979-10-09
DE2912865A1 (en) 1979-10-18

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Legal Events

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ST Notification of lapse