FR2415639A1 - Antigene de surface de l'hepatite b - Google Patents
Antigene de surface de l'hepatite bInfo
- Publication number
- FR2415639A1 FR2415639A1 FR7802322A FR7802322A FR2415639A1 FR 2415639 A1 FR2415639 A1 FR 2415639A1 FR 7802322 A FR7802322 A FR 7802322A FR 7802322 A FR7802322 A FR 7802322A FR 2415639 A1 FR2415639 A1 FR 2415639A1
- Authority
- FR
- France
- Prior art keywords
- banding
- prepn
- hepatitis
- pptn
- isopycnic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Abstract
La présente invention concerne un procédé d'obtention d'antigène de surface de l'hépatite B (en abrégé HB.Ag) à partir de liquide biologique tiré de donneurs humains ayant souffert d'hépatite B. Ce procédé est caractérisé par le fait que l'on traite le liquide par le sulfate d'ammonium en quantité suffisante pour précipiter une fraction d'antigène comprenant du HB.Ag, que l'on soumet la fraction précipitée une striation isopycnique et à une striation zonale vitesse et que l'on récupère un HB.Ag d'une gamme de masse volumique d'environ 1,13 à 1,16 g/ml. Le procédé permet d'obtenir des accroissements notables de productivité et un coût de fonctionnement notablement réduit
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7802322A FR2415639A1 (fr) | 1978-01-27 | 1978-01-27 | Antigene de surface de l'hepatite b |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7802322A FR2415639A1 (fr) | 1978-01-27 | 1978-01-27 | Antigene de surface de l'hepatite b |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2415639A1 true FR2415639A1 (fr) | 1979-08-24 |
FR2415639B1 FR2415639B1 (fr) | 1980-07-18 |
Family
ID=9203900
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7802322A Granted FR2415639A1 (fr) | 1978-01-27 | 1978-01-27 | Antigene de surface de l'hepatite b |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2415639A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2470795A1 (fr) * | 1979-12-07 | 1981-06-12 | Pasteur Institut | Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus |
-
1978
- 1978-01-27 FR FR7802322A patent/FR2415639A1/fr active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2470795A1 (fr) * | 1979-12-07 | 1981-06-12 | Pasteur Institut | Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus |
Also Published As
Publication number | Publication date |
---|---|
FR2415639B1 (fr) | 1980-07-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |