FR2415459A1 - LOCAL PREPARATIONS FOR EYE USE - Google Patents

LOCAL PREPARATIONS FOR EYE USE

Info

Publication number
FR2415459A1
FR2415459A1 FR7900789A FR7900789A FR2415459A1 FR 2415459 A1 FR2415459 A1 FR 2415459A1 FR 7900789 A FR7900789 A FR 7900789A FR 7900789 A FR7900789 A FR 7900789A FR 2415459 A1 FR2415459 A1 FR 2415459A1
Authority
FR
France
Prior art keywords
preparations
ophthalmic drug
eye
eye use
local
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7900789A
Other languages
French (fr)
Other versions
FR2415459B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of FR2415459A1 publication Critical patent/FR2415459A1/en
Application granted granted Critical
Publication of FR2415459B1 publication Critical patent/FR2415459B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des préparations locales à usage oculaire. Les préparations de l'invention sont constituées d'une dispersion aqueuse d'un médicament ophtalmique et d'un polymère de poids moléculaire élevé formant un gel très visqueux, que l'on peut utiliser pour prolonger la durée d'activité du médicament ophtalmique lorsqu'on applique le gel au sac conjonctival de l'oeil. L'invention s'applique en particulier à des compositions gélifiées contenant un médicament ophtalmique, qui ont une action prolongée avec une rétention importante au contact de l'oeil.The invention relates to local preparations for ocular use. The preparations of the invention consist of an aqueous dispersion of an ophthalmic drug and a high molecular weight polymer forming a highly viscous gel, which can be used to prolong the potency of the ophthalmic drug when 'the gel is applied to the conjunctival sac of the eye. The invention applies in particular to gelled compositions containing an ophthalmic drug, which have a prolonged action with a high retention in contact with the eye.

FR7900789A 1978-01-25 1979-01-12 LOCAL PREPARATIONS FOR EYE USE Granted FR2415459A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87207478A 1978-01-25 1978-01-25

Publications (2)

Publication Number Publication Date
FR2415459A1 true FR2415459A1 (en) 1979-08-24
FR2415459B1 FR2415459B1 (en) 1983-03-18

Family

ID=25358780

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7900789A Granted FR2415459A1 (en) 1978-01-25 1979-01-12 LOCAL PREPARATIONS FOR EYE USE

Country Status (7)

Country Link
JP (2) JPS6059885B2 (en)
CA (1) CA1108053A (en)
CH (1) CH640737A5 (en)
DE (1) DE2902863C2 (en)
FR (1) FR2415459A1 (en)
GB (1) GB2013084B (en)
MX (1) MX6520E (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE6466T1 (en) 1979-10-26 1984-03-15 Smith And Nephew Associated Companies P.L.C. AUTOCLAVABLE EMULSIONS.
GB2075837B (en) * 1980-05-14 1984-03-14 Hisamitsu Pharmaceutical Co Topical pharmaceutical gel containing anti-inflammatory analgesic agents
US6255299B1 (en) 1985-01-07 2001-07-03 Leo Pharmaceutical Products Ltd. Opthalmic gel composition and method of treating eye infections
GB8500310D0 (en) * 1985-01-07 1985-02-13 Leo Pharm Prod Ltd Pharmaceutical preparation
US5192535A (en) * 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
US5188826A (en) * 1988-02-08 1993-02-23 Insite Vision Incorporated Topical ophthalmic suspensions
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
JP2873530B2 (en) * 1991-12-13 1999-03-24 参天製薬株式会社 Carboxyvinyl polymer-containing ophthalmic base showing Newtonian viscosity
CN1049358C (en) * 1993-01-01 2000-02-16 参天制药株式会社 Carboxybinil polymer which shows newtonian viscosity
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
DE69523044T2 (en) 1994-03-04 2002-06-20 Univ Washington Seattle BLOCK AND GRAFT COPOLYMERS AND RELATED METHOD
US5683709A (en) * 1994-05-05 1997-11-04 Ciba Vision Corporation Poly(benzalkonium salt) as an anti-microbial agent for aqueous drug compositions
DE19614823A1 (en) * 1996-04-15 1997-10-16 Mann Gerhard Chem Pharm Fab Ophthalmic composition with prolonged retention time on the eye
MXPA02003731A (en) 1999-10-15 2003-12-11 Leo Pharm Prod Ltd Novel fusidic acid derivatives.
DK1654002T4 (en) * 2003-08-07 2014-02-17 Allergan Inc Compositions for applying therapeutic agents to the eyes
DE102010009475B4 (en) 2010-02-26 2011-11-24 F. Holzer Gmbh Process for the preparation of a dosable ready-to-use preparation

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1492076A1 (en) * 1964-10-06 1969-11-13 Squibb & Sons Inc Process for the production of therapeutically effective preparations containing dimethyl sulfoxide
DE2239206A1 (en) * 1971-08-12 1973-03-15 Hydrophilics Int Inc COPOLYMER
FR2191941A1 (en) * 1972-07-10 1974-02-08 Serabonian Giacomo Gelatinising water-sol and aq liqs - by addn of carboxypolymer and alginic acid salt
FR2277859A1 (en) * 1974-07-08 1976-02-06 Oreal EXCIPIENTS PREPARED FROM BASIC AMINO ACIDS AND VINYL ETHER-MALEIC ANHYDRIDE COPOLYMERS, THEIR PREPARATION AND APPLICATION
FR2285896A1 (en) * 1974-09-24 1976-04-23 Nippon Kayaku Kk PHARMACEUTICAL PREPARATION INTENDED FOR ADMINISTRATION IN THE ORAL CAVITY
US3957740A (en) * 1972-04-24 1976-05-18 Hydrophilics International, Inc. Copolymers
DE2636559A1 (en) * 1975-08-27 1977-03-17 Hydrophilics Int Inc PHARMACEUTICAL PRODUCT

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2038105A1 (en) * 1969-04-01 1971-01-08 Syntex Corp Antiinflammatory steroid preparations
DK135267A (en) * 1971-02-25
DE2265164C3 (en) * 1972-10-18 1985-08-22 Vsesojuznyj naučno-issledovatel'skij i ispytatel'nyj institut medicinskoj techniki, Moskau/Moskva Use of acrylic acid amide copolymers for the production of bases for ophthalmic drug forms
AR206692A1 (en) * 1972-12-27 1976-08-13 Alza Corp DISPENSING AGENT OF SUSTAINED RELEASE OF ACTIVE SUBSTANCES
US4003991A (en) * 1974-08-27 1977-01-18 National Patent Development Corporation Ophthalmic formulation
JPS6056684B2 (en) * 1977-11-07 1985-12-11 東興薬品工業株式会社 eye drops

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1492076A1 (en) * 1964-10-06 1969-11-13 Squibb & Sons Inc Process for the production of therapeutically effective preparations containing dimethyl sulfoxide
DE2239206A1 (en) * 1971-08-12 1973-03-15 Hydrophilics Int Inc COPOLYMER
US3957740A (en) * 1972-04-24 1976-05-18 Hydrophilics International, Inc. Copolymers
FR2191941A1 (en) * 1972-07-10 1974-02-08 Serabonian Giacomo Gelatinising water-sol and aq liqs - by addn of carboxypolymer and alginic acid salt
FR2277859A1 (en) * 1974-07-08 1976-02-06 Oreal EXCIPIENTS PREPARED FROM BASIC AMINO ACIDS AND VINYL ETHER-MALEIC ANHYDRIDE COPOLYMERS, THEIR PREPARATION AND APPLICATION
FR2285896A1 (en) * 1974-09-24 1976-04-23 Nippon Kayaku Kk PHARMACEUTICAL PREPARATION INTENDED FOR ADMINISTRATION IN THE ORAL CAVITY
DE2636559A1 (en) * 1975-08-27 1977-03-17 Hydrophilics Int Inc PHARMACEUTICAL PRODUCT

Also Published As

Publication number Publication date
FR2415459B1 (en) 1983-03-18
CA1108053A (en) 1981-09-01
GB2013084B (en) 1982-07-28
CH640737A5 (en) 1984-01-31
JPS6059885B2 (en) 1985-12-27
DE2902863C2 (en) 1994-02-24
JPS54110312A (en) 1979-08-29
JPH0428244B2 (en) 1992-05-13
JPS62215518A (en) 1987-09-22
DE2902863A1 (en) 1979-07-26
MX6520E (en) 1985-06-27
GB2013084A (en) 1979-08-08

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