FR2414915A1 - Medicament a activite prolongee pour le traitement du cancer du sein, constitue d'un melange de 2a-methyl-dihydrotestosterone, de propionate de 2a-methyl-dihydrotestosterone, de capronate de 2a-methyl-dihydrotestosterone et d'heptanoate de 2a-methyl-dihydrotestosterone - Google Patents
Medicament a activite prolongee pour le traitement du cancer du sein, constitue d'un melange de 2a-methyl-dihydrotestosterone, de propionate de 2a-methyl-dihydrotestosterone, de capronate de 2a-methyl-dihydrotestosterone et d'heptanoate de 2a-methyl-dihydrotestosteroneInfo
- Publication number
- FR2414915A1 FR2414915A1 FR7801505A FR7801505A FR2414915A1 FR 2414915 A1 FR2414915 A1 FR 2414915A1 FR 7801505 A FR7801505 A FR 7801505A FR 7801505 A FR7801505 A FR 7801505A FR 2414915 A1 FR2414915 A1 FR 2414915A1
- Authority
- FR
- France
- Prior art keywords
- acting
- long
- mammary carcinoma
- caproate
- propionate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 201000008275 breast carcinoma Diseases 0.000 title abstract 3
- FUZZWVXGSFPDMH-UHFFFAOYSA-M hexanoate Chemical compound CCCCCC([O-])=O FUZZWVXGSFPDMH-UHFFFAOYSA-M 0.000 title abstract 3
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 title abstract 2
- 239000000824 cytostatic agent Substances 0.000 title 1
- 230000001085 cytostatic effect Effects 0.000 title 1
- 229960003604 testosterone Drugs 0.000 title 1
- IKXILDNPCZPPRV-RFMGOVQKSA-N metholone Chemical compound C1C[C@@H]2[C@@]3(C)C[C@@H](C)C(=O)C[C@@H]3CC[C@H]2[C@@H]2CC[C@H](O)[C@]21C IKXILDNPCZPPRV-RFMGOVQKSA-N 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 3
- 206010027476 Metastases Diseases 0.000 abstract 1
- 206010027452 Metastases to bone Diseases 0.000 abstract 1
- 230000001195 anabolic effect Effects 0.000 abstract 1
- 230000001548 androgenic effect Effects 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- MNWFXJYAOYHMED-UHFFFAOYSA-M heptanoate Chemical compound CCCCCCC([O-])=O MNWFXJYAOYHMED-UHFFFAOYSA-M 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008063 pharmaceutical solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0025—Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7801505A FR2414915A1 (fr) | 1978-01-19 | 1978-01-19 | Medicament a activite prolongee pour le traitement du cancer du sein, constitue d'un melange de 2a-methyl-dihydrotestosterone, de propionate de 2a-methyl-dihydrotestosterone, de capronate de 2a-methyl-dihydrotestosterone et d'heptanoate de 2a-methyl-dihydrotestosterone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7801505A FR2414915A1 (fr) | 1978-01-19 | 1978-01-19 | Medicament a activite prolongee pour le traitement du cancer du sein, constitue d'un melange de 2a-methyl-dihydrotestosterone, de propionate de 2a-methyl-dihydrotestosterone, de capronate de 2a-methyl-dihydrotestosterone et d'heptanoate de 2a-methyl-dihydrotestosterone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2414915A1 true FR2414915A1 (fr) | 1979-08-17 |
| FR2414915B1 FR2414915B1 (en, 2012) | 1981-06-12 |
Family
ID=9203649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7801505A Granted FR2414915A1 (fr) | 1978-01-19 | 1978-01-19 | Medicament a activite prolongee pour le traitement du cancer du sein, constitue d'un melange de 2a-methyl-dihydrotestosterone, de propionate de 2a-methyl-dihydrotestosterone, de capronate de 2a-methyl-dihydrotestosterone et d'heptanoate de 2a-methyl-dihydrotestosterone |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2414915A1 (en, 2012) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3118915A (en) * | 1959-02-24 | 1964-01-21 | Syntex Corp | 2alpha-lower alkyl dihydro testosterone and derivatives thereof |
-
1978
- 1978-01-19 FR FR7801505A patent/FR2414915A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3118915A (en) * | 1959-02-24 | 1964-01-21 | Syntex Corp | 2alpha-lower alkyl dihydro testosterone and derivatives thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2414915B1 (en, 2012) | 1981-06-12 |
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| FR2414915A1 (fr) | Medicament a activite prolongee pour le traitement du cancer du sein, constitue d'un melange de 2a-methyl-dihydrotestosterone, de propionate de 2a-methyl-dihydrotestosterone, de capronate de 2a-methyl-dihydrotestosterone et d'heptanoate de 2a-methyl-dihydrotestosterone | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |