FR2396761A1 - PROCESS FOR THE PREPARATION OF R, S-2,3,5,6-TETRAHYDRO-6-PHENYL-IMIDAZO (2,1-B) -THIAZOLE AND ITS PHARMACEUTICALLY ACCEPTABLE ACID ADDITIONAL SALTS, USING AN ALKYLXANTHOGENATE OR THIOPHENE - Google Patents

PROCESS FOR THE PREPARATION OF R, S-2,3,5,6-TETRAHYDRO-6-PHENYL-IMIDAZO (2,1-B) -THIAZOLE AND ITS PHARMACEUTICALLY ACCEPTABLE ACID ADDITIONAL SALTS, USING AN ALKYLXANTHOGENATE OR THIOPHENE

Info

Publication number
FR2396761A1
FR2396761A1 FR7820188A FR7820188A FR2396761A1 FR 2396761 A1 FR2396761 A1 FR 2396761A1 FR 7820188 A FR7820188 A FR 7820188A FR 7820188 A FR7820188 A FR 7820188A FR 2396761 A1 FR2396761 A1 FR 2396761A1
Authority
FR
France
Prior art keywords
imidazo
thiazole
tetrahydro
phenyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7820188A
Other languages
French (fr)
Other versions
FR2396761B1 (en
Inventor
Atanas Georgiev Georgiev
Christo Petrov Daskalov
Venzel Georgiev Michajlov
Kina Vesselinova Konstantinova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmachim DSO
Original Assignee
Pharmachim DSO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmachim DSO filed Critical Pharmachim DSO
Publication of FR2396761A1 publication Critical patent/FR2396761A1/en
Application granted granted Critical
Publication of FR2396761B1 publication Critical patent/FR2396761B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

a. Procédé de préparation du R,S-2,3,5,6-tétrahydro-6-phényl-imidazo (2,1-b)-thiazole. b. Il consiste à faire réagir la R,S- alpha -(2-hydroxyéthylaminométhyl)-benzylamine avec un composé de formule :at. Process for the preparation of R, S-2,3,5,6-tetrahydro-6-phenyl-imidazo (2,1-b) -thiazole. b. It consists of reacting R, S- alpha - (2-hydroxyethylaminomethyl) -benzylamine with a compound of formula:

FR7820188A 1977-07-06 1978-07-06 PROCESS FOR THE PREPARATION OF R, S-2,3,5,6-TETRAHYDRO-6-PHENYL-IMIDAZO (2,1-B) -THIAZOLE AND ITS PHARMACEUTICALLY ACCEPTABLE ACID ADDITIONAL SALTS, USING AN ALKYLXANTHOGENATE OR THIOPHENE Granted FR2396761A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG3790777 1977-07-06

Publications (2)

Publication Number Publication Date
FR2396761A1 true FR2396761A1 (en) 1979-02-02
FR2396761B1 FR2396761B1 (en) 1981-12-18

Family

ID=3904004

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7820188A Granted FR2396761A1 (en) 1977-07-06 1978-07-06 PROCESS FOR THE PREPARATION OF R, S-2,3,5,6-TETRAHYDRO-6-PHENYL-IMIDAZO (2,1-B) -THIAZOLE AND ITS PHARMACEUTICALLY ACCEPTABLE ACID ADDITIONAL SALTS, USING AN ALKYLXANTHOGENATE OR THIOPHENE

Country Status (12)

Country Link
JP (1) JPS5414997A (en)
BE (1) BE868744A (en)
CA (1) CA1100508A (en)
DE (1) DE2829822A1 (en)
ES (1) ES471356A1 (en)
FR (1) FR2396761A1 (en)
GB (1) GB2002350B (en)
HU (1) HU181927B (en)
IT (1) IT1174324B (en)
NL (1) NL7807266A (en)
SU (1) SU922107A1 (en)
YU (1) YU162278A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5330897U (en) * 1976-08-24 1978-03-16
CA1135270A (en) * 1978-11-06 1982-11-09 American Cyanamid Company Processes for the preparation of tetramisole and novel intermediates
DE2963498D1 (en) * 1978-11-06 1982-09-30 American Cyanamid Co Process for the preparation of tetramisole

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3726894A (en) * 1971-06-24 1973-04-10 American Cyanamid Co The compound 1-(2-hydroxyethyl)-4-phenyl-2-imidazolidinethione
FR2209576A1 (en) * 1972-12-08 1974-07-05 Janssen Pharmaceutica Nv

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3726894A (en) * 1971-06-24 1973-04-10 American Cyanamid Co The compound 1-(2-hydroxyethyl)-4-phenyl-2-imidazolidinethione
FR2209576A1 (en) * 1972-12-08 1974-07-05 Janssen Pharmaceutica Nv

Also Published As

Publication number Publication date
NL7807266A (en) 1979-01-09
CA1100508A (en) 1981-05-05
GB2002350B (en) 1982-02-10
FR2396761B1 (en) 1981-12-18
BE868744A (en) 1978-11-03
YU162278A (en) 1982-08-31
JPS5414997A (en) 1979-02-03
HU181927B (en) 1983-11-28
IT7850170A0 (en) 1978-07-05
IT1174324B (en) 1987-07-01
GB2002350A (en) 1979-02-21
DE2829822A1 (en) 1979-02-01
SU922107A1 (en) 1982-04-23
ES471356A1 (en) 1979-09-16

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