FR2381007A1 - PROCESS FOR THE PREPARATION OF PATCHOULOL DERIVATIVES - Google Patents

PROCESS FOR THE PREPARATION OF PATCHOULOL DERIVATIVES

Info

Publication number
FR2381007A1
FR2381007A1 FR7726429A FR7726429A FR2381007A1 FR 2381007 A1 FR2381007 A1 FR 2381007A1 FR 7726429 A FR7726429 A FR 7726429A FR 7726429 A FR7726429 A FR 7726429A FR 2381007 A1 FR2381007 A1 FR 2381007A1
Authority
FR
France
Prior art keywords
patchoulol
derivatives
preparation
synthesis
norpatchoulenol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7726429A
Other languages
French (fr)
Other versions
FR2381007B1 (en
Inventor
Elisabeth Becher
Willy Schuep
Peter Karl Matzinger
Paul Jose Teisseire
Charles Ehret
Hiromi Maruyama
Yasuji Suraha
Sayuri Ito
Mayumi Ogawa
Kazuteru Yokose
Toyoaki Sawada
Akiko Fujiwara
Mitsuhiko Fujiwara
Massaki Tazoe
Yoshihiko Shiomi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2381007A1 publication Critical patent/FR2381007A1/en
Application granted granted Critical
Publication of FR2381007B1 publication Critical patent/FR2381007B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/21—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen
    • C07C51/23—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups
    • C07C51/235—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups of —CHO groups or primary alcohol groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne la synthèse de dérivés de patchoulol. Il s'agit d'un procédé pour l'hydroxylation de patchoulol, caractérisé en ce que le patchoulol est hydroxyle dans des conditions aérobies aqueuses en présence d'un micro-organisme oxydant. Ce procédé ouvre la voie à un procédé synthétique partiel de synthese du norpatchoulénol à partir du patchoulol relativement abondant.The invention relates to the synthesis of patchoulol derivatives. This is a process for the hydroxylation of patchoulol, characterized in that the patchoulol is hydroxylated under aqueous aerobic conditions in the presence of an oxidizing microorganism. This process opens the way to a partial synthetic process for the synthesis of norpatchoulenol from relatively abundant patchoulol.

FR7726429A 1977-08-31 1977-08-31 PROCESS FOR THE PREPARATION OF PATCHOULOL DERIVATIVES Granted FR2381007A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3639776A GB1586859A (en) 1977-08-31 1977-08-31 Process for the preparation of patchoulol derivatives

Publications (2)

Publication Number Publication Date
FR2381007A1 true FR2381007A1 (en) 1978-09-15
FR2381007B1 FR2381007B1 (en) 1980-10-17

Family

ID=10387766

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7726429A Granted FR2381007A1 (en) 1977-08-31 1977-08-31 PROCESS FOR THE PREPARATION OF PATCHOULOL DERIVATIVES
FR7811548A Granted FR2381008A1 (en) 1977-08-31 1978-04-19 NEW HYDROXYL PATCHOULOLS

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7811548A Granted FR2381008A1 (en) 1977-08-31 1978-04-19 NEW HYDROXYL PATCHOULOLS

Country Status (7)

Country Link
JP (1) JPS5332195A (en)
BE (1) BE858326A (en)
DE (1) DE2739449A1 (en)
FR (2) FR2381007A1 (en)
GB (1) GB1586859A (en)
IT (1) IT1084200B (en)
NL (1) NL7709693A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2960378D1 (en) * 1978-08-10 1981-08-27 Givaudan & Cie Sa Methanonaphthalene, as well as a process for its preparation and its use for the preparation of norpatchoulenol
JPS5593646A (en) * 1978-12-30 1980-07-16 Matsushita Electric Works Ltd Fluorescent lamp
ZA200700473B (en) * 2006-01-16 2009-08-26 Reliance Life Sciences Pvt Ltd Process for increased patchulol content in essential oil of pogostemon cablin

Also Published As

Publication number Publication date
FR2381008A1 (en) 1978-09-15
GB1586859A (en) 1981-03-25
JPS5332195A (en) 1978-03-27
DE2739449A1 (en) 1978-03-23
BE858326A (en) 1978-03-01
IT1084200B (en) 1985-05-25
FR2381007B1 (en) 1980-10-17
FR2381008B1 (en) 1981-09-04
NL7709693A (en) 1978-03-06

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Legal Events

Date Code Title Description
ST Notification of lapse