FR2372144A1 - METHOD FOR THE PREPARATION OF L-SERINE - Google Patents

METHOD FOR THE PREPARATION OF L-SERINE

Info

Publication number
FR2372144A1
FR2372144A1 FR7736100A FR7736100A FR2372144A1 FR 2372144 A1 FR2372144 A1 FR 2372144A1 FR 7736100 A FR7736100 A FR 7736100A FR 7736100 A FR7736100 A FR 7736100A FR 2372144 A1 FR2372144 A1 FR 2372144A1
Authority
FR
France
Prior art keywords
serine
glycocoll
preparation
glycocolle
purine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7736100A
Other languages
French (fr)
Other versions
FR2372144B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP14374876A external-priority patent/JPS5369883A/en
Priority claimed from JP14738976A external-priority patent/JPS5372893A/en
Priority claimed from JP14739076A external-priority patent/JPS5372894A/en
Priority claimed from JP15302476A external-priority patent/JPS5379096A/en
Priority claimed from JP4253677A external-priority patent/JPS5910194B2/en
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of FR2372144A1 publication Critical patent/FR2372144A1/en
Application granted granted Critical
Publication of FR2372144B1 publication Critical patent/FR2372144B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne un procédé de préparation de L-sérine. Il s'agit d'un procédé pour la préparation de L-sérine, caractérisé par le fait que l'on transforme du glycocolle en L-sérine dans un milieu aqueux contenant du glycocolle en présence de cellules microbiennes d'un mutant appartenant au genre Nocardia capable de transformer le glycocolle en L-sérine et n'ayant qu'une aptitude faible ou nulle à décomposer la L-sérine et/ou présentant une certaine résistance à l'un au moins des antagonistes métaboliques choisis parmi ceux du glycocolle, de la sérine, de la methionine, de la glutamine, de l'histidine, de la leucine, de l'isoleucine, de la valine, de la purine, de la pyrimidine ou de l'acide folique, on accumule la L-sérine dans le milieu et on la recueille à partir de celui-ci. Ce procédé permet d'obtenir des rendements élevés.The invention relates to a process for preparing L-serine. This is a process for the preparation of L-serine, characterized by the fact that glycocolle is transformed into L-serine in an aqueous medium containing glycocoll in the presence of microbial cells of a mutant belonging to the genus Nocardia capable of transforming glycocoll into L-serine and having little or no ability to decompose L-serine and / or exhibiting some resistance to at least one of the metabolic antagonists chosen from those of glycocoll, serine, methionine, glutamine, histidine, leucine, isoleucine, valine, purine, pyrimidine or folic acid, L-serine is accumulated in the middle and we collect it from it. This process makes it possible to obtain high yields.

FR7736100A 1976-11-30 1977-11-30 METHOD FOR THE PREPARATION OF L-SERINE Granted FR2372144A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP14374876A JPS5369883A (en) 1976-11-30 1976-11-30 Preparation of l-serine by fermentation
JP14738976A JPS5372893A (en) 1976-12-08 1976-12-08 Preparation of l-serine by fermentation
JP14739076A JPS5372894A (en) 1976-12-08 1976-12-08 Preparation of l-serine by fermentation
JP15302476A JPS5379096A (en) 1976-12-20 1976-12-20 Preparation of l-serine by fermentation
JP4253677A JPS5910194B2 (en) 1977-04-15 1977-04-15 Production method of L-serine

Publications (2)

Publication Number Publication Date
FR2372144A1 true FR2372144A1 (en) 1978-06-23
FR2372144B1 FR2372144B1 (en) 1981-01-09

Family

ID=27522260

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7736100A Granted FR2372144A1 (en) 1976-11-30 1977-11-30 METHOD FOR THE PREPARATION OF L-SERINE

Country Status (4)

Country Link
CA (1) CA1097240A (en)
DE (1) DE2753422C3 (en)
FR (1) FR2372144A1 (en)
GB (1) GB1592499A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2555198A1 (en) * 1983-11-22 1985-05-24 Grace W R Ltd METHOD FOR ENHANCING A MICROORGANISM STRAIN FOR THE PREPARATION OF L-SERINE BY FERMENTATION AND THE STRAIN OBTAINED
EP0213736A2 (en) * 1985-07-29 1987-03-11 MITSUI TOATSU CHEMICALS, Inc. Method for separating glycine and L-serine from a solution containing same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005049527B4 (en) 2005-10-17 2013-05-08 Forschungszentrum Jülich GmbH Process for the preparation of L-serine, gene sequence, vectors and microorganism

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS516236B2 (en) * 1972-11-24 1976-02-26

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1974 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2555198A1 (en) * 1983-11-22 1985-05-24 Grace W R Ltd METHOD FOR ENHANCING A MICROORGANISM STRAIN FOR THE PREPARATION OF L-SERINE BY FERMENTATION AND THE STRAIN OBTAINED
EP0213736A2 (en) * 1985-07-29 1987-03-11 MITSUI TOATSU CHEMICALS, Inc. Method for separating glycine and L-serine from a solution containing same
EP0213736A3 (en) * 1985-07-29 1987-11-11 Mitsui Toatsu Chemicals, Incorporated Method for separating glycine and l-serine from a solution containing same

Also Published As

Publication number Publication date
DE2753422B2 (en) 1980-07-03
DE2753422C3 (en) 1981-03-19
FR2372144B1 (en) 1981-01-09
GB1592499A (en) 1981-07-08
CA1097240A (en) 1981-03-10
DE2753422A1 (en) 1978-06-01

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