FR2367494A1 - Nouveaux derives de nitrosouree et procede pour leur preparation - Google Patents
Nouveaux derives de nitrosouree et procede pour leur preparationInfo
- Publication number
- FR2367494A1 FR2367494A1 FR7631482A FR7631482A FR2367494A1 FR 2367494 A1 FR2367494 A1 FR 2367494A1 FR 7631482 A FR7631482 A FR 7631482A FR 7631482 A FR7631482 A FR 7631482A FR 2367494 A1 FR2367494 A1 FR 2367494A1
- Authority
- FR
- France
- Prior art keywords
- substd
- leukaemia
- low toxicity
- days
- tumour agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000032839 leukemia Diseases 0.000 title abstract 3
- -1 N-nitroso ureido Chemical group 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 231100000053 low toxicity Toxicity 0.000 title abstract 2
- 235000000346 sugar Nutrition 0.000 title 1
- 150000008163 sugars Chemical class 0.000 title 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- 241000030360 Peromyscus truei Species 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940045719 antineoplastic alkylating agent nitrosoureas Drugs 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 1
- 125000003147 glycosyl group Chemical group 0.000 abstract 1
- 238000011081 inoculation Methods 0.000 abstract 1
- 230000009935 nitrosation Effects 0.000 abstract 1
- 238000007034 nitrosation reaction Methods 0.000 abstract 1
- 229930190553 ribostamycin Natural products 0.000 abstract 1
- NSKGQURZWSPSBC-NLZFXWNVSA-N ribostamycin Chemical compound N[C@H]1[C@H](O)[C@@H](O)[C@H](CN)O[C@@H]1O[C@@H]1[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@H](CO)O2)O)[C@H](O)[C@@H](N)C[C@H]1N NSKGQURZWSPSBC-NLZFXWNVSA-N 0.000 abstract 1
- 229960003485 ribostamycin Drugs 0.000 abstract 1
- NSKGQURZWSPSBC-UHFFFAOYSA-N ribostamycin A Natural products NC1C(O)C(O)C(CN)OC1OC1C(OC2C(C(O)C(CO)O2)O)C(O)C(N)CC1N NSKGQURZWSPSBC-UHFFFAOYSA-N 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7631482A FR2367494A1 (fr) | 1976-10-18 | 1976-10-18 | Nouveaux derives de nitrosouree et procede pour leur preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7631482A FR2367494A1 (fr) | 1976-10-18 | 1976-10-18 | Nouveaux derives de nitrosouree et procede pour leur preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2367494A1 true FR2367494A1 (fr) | 1978-05-12 |
| FR2367494B1 FR2367494B1 (OSRAM) | 1980-09-26 |
Family
ID=9178965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7631482A Granted FR2367494A1 (fr) | 1976-10-18 | 1976-10-18 | Nouveaux derives de nitrosouree et procede pour leur preparation |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2367494A1 (OSRAM) |
-
1976
- 1976-10-18 FR FR7631482A patent/FR2367494A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2367494B1 (OSRAM) | 1980-09-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |