FR2367489A1 - NEW ESTERS OF 2-HYDROXYMETHYL-2-PHENYL-1,3-INDANEDIONE - Google Patents

NEW ESTERS OF 2-HYDROXYMETHYL-2-PHENYL-1,3-INDANEDIONE

Info

Publication number
FR2367489A1
FR2367489A1 FR7631284A FR7631284A FR2367489A1 FR 2367489 A1 FR2367489 A1 FR 2367489A1 FR 7631284 A FR7631284 A FR 7631284A FR 7631284 A FR7631284 A FR 7631284A FR 2367489 A1 FR2367489 A1 FR 2367489A1
Authority
FR
France
Prior art keywords
phenyl
indanedione
hydroxymethyl
esters
new esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7631284A
Other languages
French (fr)
Other versions
FR2367489B1 (en
Inventor
Jacques Viret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SEMS
Original Assignee
SEMS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SEMS filed Critical SEMS
Priority to FR7631284A priority Critical patent/FR2367489A1/en
Priority to CH1163477A priority patent/CH624379A5/en
Priority to DE19772744809 priority patent/DE2744809A1/en
Priority to BE2056343A priority patent/BE859783A/en
Priority to ES463298A priority patent/ES463298A1/en
Publication of FR2367489A1 publication Critical patent/FR2367489A1/en
Application granted granted Critical
Publication of FR2367489B1 publication Critical patent/FR2367489B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

New industrial products, the 2-hydroxymethyl-2-phenyl-1,3-indanedione esters of formula: where R is especially a phenyl, phenoxyalkyl, phenylalkyl, heterocyclic or CH2CH2CO2R' group, where R' is especially H, phenyl, phenylalkyl or heterocyclic, are prepared by reaction of 2-hydroxymethyl-2-phenyl-1,3-indanedione with an acid of formula RCOOH or one of its functional derivatives. These esters are useful in therapeutics, especially as anticoagulating agents for the prevention and the treatment of thromboses.
FR7631284A 1976-10-18 1976-10-18 NEW ESTERS OF 2-HYDROXYMETHYL-2-PHENYL-1,3-INDANEDIONE Granted FR2367489A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR7631284A FR2367489A1 (en) 1976-10-18 1976-10-18 NEW ESTERS OF 2-HYDROXYMETHYL-2-PHENYL-1,3-INDANEDIONE
CH1163477A CH624379A5 (en) 1976-10-18 1977-09-23 Process for the preparation of new 2-hydroxymethyl-2-phenyl-1,3-indanedione esters
DE19772744809 DE2744809A1 (en) 1976-10-18 1977-10-05 NEW ESTERS OF 2-HYDROXYMETHYL-2-PHENYL-1,3-INDANDIONE
BE2056343A BE859783A (en) 1976-10-18 1977-10-17 NEW ESTERS OF 2-HYDROXYMETHYL-2-PHENYL-1,3-INDANEDIONE
ES463298A ES463298A1 (en) 1976-10-18 1977-10-17 Procedure for the preparation of a new ester of 2-hydroxymethyl-2-phenyl-1,3-indanodiona. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7631284A FR2367489A1 (en) 1976-10-18 1976-10-18 NEW ESTERS OF 2-HYDROXYMETHYL-2-PHENYL-1,3-INDANEDIONE

Publications (2)

Publication Number Publication Date
FR2367489A1 true FR2367489A1 (en) 1978-05-12
FR2367489B1 FR2367489B1 (en) 1979-03-02

Family

ID=9178872

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7631284A Granted FR2367489A1 (en) 1976-10-18 1976-10-18 NEW ESTERS OF 2-HYDROXYMETHYL-2-PHENYL-1,3-INDANEDIONE

Country Status (5)

Country Link
BE (1) BE859783A (en)
CH (1) CH624379A5 (en)
DE (1) DE2744809A1 (en)
ES (1) ES463298A1 (en)
FR (1) FR2367489A1 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Also Published As

Publication number Publication date
DE2744809A1 (en) 1978-04-20
CH624379A5 (en) 1981-07-31
FR2367489B1 (en) 1979-03-02
ES463298A1 (en) 1978-07-16
BE859783A (en) 1978-04-17

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Legal Events

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