FR2364217A1 - Procede pour la preparation de derives de l'acide 6-aminopenicillanique - Google Patents

Procede pour la preparation de derives de l'acide 6-aminopenicillanique

Info

Publication number
FR2364217A1
FR2364217A1 FR7627003A FR7627003A FR2364217A1 FR 2364217 A1 FR2364217 A1 FR 2364217A1 FR 7627003 A FR7627003 A FR 7627003A FR 7627003 A FR7627003 A FR 7627003A FR 2364217 A1 FR2364217 A1 FR 2364217A1
Authority
FR
France
Prior art keywords
alpha
mixed anhydride
prepn
penicillins
benzyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7627003A
Other languages
English (en)
Other versions
FR2364217B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocraft Laboratories Inc
Original Assignee
Biocraft Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocraft Laboratories Inc filed Critical Biocraft Laboratories Inc
Priority to FR7627003A priority Critical patent/FR2364217A1/fr
Publication of FR2364217A1 publication Critical patent/FR2364217A1/fr
Application granted granted Critical
Publication of FR2364217B1 publication Critical patent/FR2364217B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Procédé pour la préparation d'alpha-aminobenzyl-pénicillines, éventuellement substituées. On dissout de l'acide 6-aminopénicillanique ou un de ses sels solubles dans l'eau pour former une première solution; on sépare, par exemple par filtration, des impuretés contaminantes solides à partir de cette première solution; on forme une deuxième solution en dissolvant un agent acylant du type anhydride mixte dans un solvant organique, on refroidit cette deuxième solution jusqu'à environ - 50 degrés C, on en sépare des impuretés contaminantes solides, et on combine les deux solutions afin de les faire réagir pour produire l'alpha-aminobenzylpénicilline désirée. Obtention, à un haut rendement, des pénicillines en question à un haut degré de pureté.
FR7627003A 1976-09-08 1976-09-08 Procede pour la preparation de derives de l'acide 6-aminopenicillanique Granted FR2364217A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7627003A FR2364217A1 (fr) 1976-09-08 1976-09-08 Procede pour la preparation de derives de l'acide 6-aminopenicillanique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7627003A FR2364217A1 (fr) 1976-09-08 1976-09-08 Procede pour la preparation de derives de l'acide 6-aminopenicillanique

Publications (2)

Publication Number Publication Date
FR2364217A1 true FR2364217A1 (fr) 1978-04-07
FR2364217B1 FR2364217B1 (fr) 1979-05-11

Family

ID=9177477

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7627003A Granted FR2364217A1 (fr) 1976-09-08 1976-09-08 Procede pour la preparation de derives de l'acide 6-aminopenicillanique

Country Status (1)

Country Link
FR (1) FR2364217A1 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2165409A5 (fr) * 1971-12-17 1973-08-03 Cipan Cie Ind Prod Antib

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2165409A5 (fr) * 1971-12-17 1973-08-03 Cipan Cie Ind Prod Antib

Also Published As

Publication number Publication date
FR2364217B1 (fr) 1979-05-11

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