FR2360306A1 - Analgesic and antibacterial agents - esp. for dental application contg. a salicylic acid deriv. and a nitro-furan - Google Patents
Analgesic and antibacterial agents - esp. for dental application contg. a salicylic acid deriv. and a nitro-furanInfo
- Publication number
- FR2360306A1 FR2360306A1 FR7623776A FR7623776A FR2360306A1 FR 2360306 A1 FR2360306 A1 FR 2360306A1 FR 7623776 A FR7623776 A FR 7623776A FR 7623776 A FR7623776 A FR 7623776A FR 2360306 A1 FR2360306 A1 FR 2360306A1
- Authority
- FR
- France
- Prior art keywords
- analgesic
- esp
- nitro
- salicyl
- nitrofuran
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
New medicaments contain (a) a salicyl deriv. and (b) anti-bacterial cpds. of the nitrofuran series with synergistic activity w.r.t. analgesic and antiseptic properties. The ratio of salicyl deriv. to nitrofuran cpd. is generally 4:1. Typical salicyl derivs. are aspirin, diethylsalicylamide, salicylamide, and choline salicylate. Typical nitrofurans are 5-nitrofurfurylideneaminohydantoin and 3-morpholinomethyl-5-nitro-furfurylideneamino-2,4-imidazolidine-2- ,4-dione (nurfurfolin). The medicaments can be used for treating various painful or infectious syndromes, esp. in bone tissue and in the oral/dental area. There is mutual synergism between thesalicyl and nitrofuran components, so that both analgesic and antibacterial effects are increased. The toxicity of the medicaments is low, and they are practically without effect on blood clotting.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7623776A FR2360306A1 (en) | 1976-08-03 | 1976-08-03 | Analgesic and antibacterial agents - esp. for dental application contg. a salicylic acid deriv. and a nitro-furan |
DE19772733505 DE2733505A1 (en) | 1976-08-03 | 1977-07-25 | DRUG |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7623776A FR2360306A1 (en) | 1976-08-03 | 1976-08-03 | Analgesic and antibacterial agents - esp. for dental application contg. a salicylic acid deriv. and a nitro-furan |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2360306A1 true FR2360306A1 (en) | 1978-03-03 |
FR2360306B1 FR2360306B1 (en) | 1978-12-22 |
Family
ID=9176539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7623776A Granted FR2360306A1 (en) | 1976-08-03 | 1976-08-03 | Analgesic and antibacterial agents - esp. for dental application contg. a salicylic acid deriv. and a nitro-furan |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE2733505A1 (en) |
FR (1) | FR2360306A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2512342A1 (en) * | 1981-09-04 | 1983-03-11 | Glaxo Group Ltd | PHARMACEUTICAL COMPOSITION CONTAINING AN ANTI-INFLAMMATORY MEDICINAL PRODUCT AND RANITIDINE OR A SALT THEREOF |
-
1976
- 1976-08-03 FR FR7623776A patent/FR2360306A1/en active Granted
-
1977
- 1977-07-25 DE DE19772733505 patent/DE2733505A1/en active Pending
Non-Patent Citations (1)
Title |
---|
NEANT * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2512342A1 (en) * | 1981-09-04 | 1983-03-11 | Glaxo Group Ltd | PHARMACEUTICAL COMPOSITION CONTAINING AN ANTI-INFLAMMATORY MEDICINAL PRODUCT AND RANITIDINE OR A SALT THEREOF |
Also Published As
Publication number | Publication date |
---|---|
FR2360306B1 (en) | 1978-12-22 |
DE2733505A1 (en) | 1978-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |