FR2359137A1 - Procede pour faire reagir des 1,3-dithianes substitues en 2-aromatiques avec des cetones insaturees en a,b pour produire selectivement des produits d'addition en 1,4 ou 1,2, produits obtenus par le procede et application desdits produits comme agents anti-hypertension - Google Patents
Procede pour faire reagir des 1,3-dithianes substitues en 2-aromatiques avec des cetones insaturees en a,b pour produire selectivement des produits d'addition en 1,4 ou 1,2, produits obtenus par le procede et application desdits produits comme agents anti-hypertensionInfo
- Publication number
- FR2359137A1 FR2359137A1 FR7722601A FR7722601A FR2359137A1 FR 2359137 A1 FR2359137 A1 FR 2359137A1 FR 7722601 A FR7722601 A FR 7722601A FR 7722601 A FR7722601 A FR 7722601A FR 2359137 A1 FR2359137 A1 FR 2359137A1
- Authority
- FR
- France
- Prior art keywords
- products
- reacting
- substituted
- dithianes
- aromatics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000004889 1,3-dithianes Chemical group 0.000 title abstract 3
- 150000002576 ketones Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 230000008569 process Effects 0.000 title abstract 3
- 239000002220 antihypertensive agent Substances 0.000 title 1
- WQADWIOXOXRPLN-UHFFFAOYSA-N 1,3-Dithiane Natural products C1CSCSC1 WQADWIOXOXRPLN-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 229940125692 cardiovascular agent Drugs 0.000 abstract 1
- 239000002327 cardiovascular agent Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/707,965 US4089876A (en) | 1976-07-23 | 1976-07-23 | Method for reacting 2-aromatic substituted 1,3-dithianes with α,.beta. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2359137A1 true FR2359137A1 (fr) | 1978-02-17 |
| FR2359137B1 FR2359137B1 (enExample) | 1981-09-18 |
Family
ID=24843865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7722601A Granted FR2359137A1 (fr) | 1976-07-23 | 1977-07-22 | Procede pour faire reagir des 1,3-dithianes substitues en 2-aromatiques avec des cetones insaturees en a,b pour produire selectivement des produits d'addition en 1,4 ou 1,2, produits obtenus par le procede et application desdits produits comme agents anti-hypertension |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4089876A (enExample) |
| JP (1) | JPS5315388A (enExample) |
| CA (1) | CA1114388A (enExample) |
| FR (1) | FR2359137A1 (enExample) |
| GB (1) | GB1585972A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105085471B (zh) * | 2014-05-16 | 2019-06-11 | 兰州大学 | 一种2-取代-1，3-二噻烷衍生物的制备方法 |
-
1976
- 1976-07-23 US US05/707,965 patent/US4089876A/en not_active Expired - Lifetime
-
1977
- 1977-07-15 CA CA282,776A patent/CA1114388A/en not_active Expired
- 1977-07-19 GB GB30315/77A patent/GB1585972A/en not_active Expired
- 1977-07-22 JP JP8750977A patent/JPS5315388A/ja active Pending
- 1977-07-22 FR FR7722601A patent/FR2359137A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| US4089876A (en) | 1978-05-16 |
| GB1585972A (en) | 1981-03-11 |
| FR2359137B1 (enExample) | 1981-09-18 |
| JPS5315388A (en) | 1978-02-13 |
| CA1114388A (en) | 1981-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |