FR2358411A1 - NEW DERIVATIVES OF 7-AMINO-CEPHALOSPORANIC ACID AND THEIR OBTAINING - Google Patents

NEW DERIVATIVES OF 7-AMINO-CEPHALOSPORANIC ACID AND THEIR OBTAINING

Info

Publication number
FR2358411A1
FR2358411A1 FR7721814A FR7721814A FR2358411A1 FR 2358411 A1 FR2358411 A1 FR 2358411A1 FR 7721814 A FR7721814 A FR 7721814A FR 7721814 A FR7721814 A FR 7721814A FR 2358411 A1 FR2358411 A1 FR 2358411A1
Authority
FR
France
Prior art keywords
amino
obtaining
new derivatives
cephalosporanic acid
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7721814A
Other languages
French (fr)
Other versions
FR2358411B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/771,859 external-priority patent/US4103085A/en
Priority claimed from US05/777,986 external-priority patent/US4112228A/en
Priority claimed from US05/788,056 external-priority patent/US4104469A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2358411A1 publication Critical patent/FR2358411A1/en
Application granted granted Critical
Publication of FR2358411B1 publication Critical patent/FR2358411B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

L'invention décrit l'obtention de nouveaux dérivés de cet acide. Ils ont pour formule :The invention describes the production of new derivatives of this acid. They have the following formula:

FR7721814A 1976-07-13 1977-07-13 NEW DERIVATIVES OF 7-AMINO-CEPHALOSPORANIC ACID AND THEIR OBTAINING Granted FR2358411A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70522676A 1976-07-13 1976-07-13
US05/771,859 US4103085A (en) 1977-02-24 1977-02-24 7-(Syn-α-alkoxy-iminofurylacetamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
US05/777,986 US4112228A (en) 1976-07-13 1977-03-16 7-(D-α-Hydroxy-2-arylacetamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo-[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids and derivatives
US05/788,056 US4104469A (en) 1977-04-15 1977-04-15 7-(Syn-α-alkoxy-iminofuryl)acetamido-3-(2-methyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids

Publications (2)

Publication Number Publication Date
FR2358411A1 true FR2358411A1 (en) 1978-02-10
FR2358411B1 FR2358411B1 (en) 1981-06-12

Family

ID=27505490

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7721814A Granted FR2358411A1 (en) 1976-07-13 1977-07-13 NEW DERIVATIVES OF 7-AMINO-CEPHALOSPORANIC ACID AND THEIR OBTAINING

Country Status (16)

Country Link
JP (1) JPS5328191A (en)
AU (1) AU511805B2 (en)
BE (1) BE856785A (en)
CA (1) CA1142918A (en)
CH (1) CH640239A5 (en)
DE (1) DE2731724A1 (en)
DK (1) DK143344C (en)
FI (1) FI772179A (en)
FR (1) FR2358411A1 (en)
GB (1) GB1561236A (en)
GR (1) GR81280B (en)
IE (1) IE45548B1 (en)
LU (1) LU77756A1 (en)
NL (1) NL7707820A (en)
SE (2) SE7708053L (en)
YU (1) YU171977A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228061A2 (en) * 1985-12-23 1987-07-08 Takeda Chemical Industries, Ltd. Cephem compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228061A2 (en) * 1985-12-23 1987-07-08 Takeda Chemical Industries, Ltd. Cephem compounds
EP0228061A3 (en) * 1985-12-23 1988-12-14 Takeda Chemical Industries, Ltd. Cephem compounds

Also Published As

Publication number Publication date
DK312677A (en) 1978-01-14
IE45548B1 (en) 1982-09-22
FI772179A (en) 1978-01-14
SE7708053L (en) 1978-01-14
LU77756A1 (en) 1978-02-08
DK143344B (en) 1981-08-10
CA1142918A (en) 1983-03-15
AU2698277A (en) 1979-01-18
DK143344C (en) 1981-12-14
DE2731724A1 (en) 1978-01-19
GB1561236A (en) 1980-02-13
SE8205482L (en) 1982-09-24
FR2358411B1 (en) 1981-06-12
NL7707820A (en) 1978-01-17
SE8205482D0 (en) 1982-09-24
CH640239A5 (en) 1983-12-30
AU511805B2 (en) 1980-09-04
JPS5328191A (en) 1978-03-16
IE45548L (en) 1978-01-13
BE856785A (en) 1978-01-13
GR81280B (en) 1984-12-11
YU171977A (en) 1982-06-30

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Legal Events

Date Code Title Description
ST Notification of lapse