FR2358400A1 - NEW QUINOXALINE DI-N-OXIDES, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCT CONTAINING THEM - Google Patents

NEW QUINOXALINE DI-N-OXIDES, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCT CONTAINING THEM

Info

Publication number
FR2358400A1
FR2358400A1 FR7721702A FR7721702A FR2358400A1 FR 2358400 A1 FR2358400 A1 FR 2358400A1 FR 7721702 A FR7721702 A FR 7721702A FR 7721702 A FR7721702 A FR 7721702A FR 2358400 A1 FR2358400 A1 FR 2358400A1
Authority
FR
France
Prior art keywords
oxides
preparation process
product containing
medicinal product
quinoxaline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7721702A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19762631520 external-priority patent/DE2631520A1/en
Priority claimed from DE19762638732 external-priority patent/DE2638732A1/en
Application filed by Bayer AG filed Critical Bayer AG
Publication of FR2358400A1 publication Critical patent/FR2358400A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne de nouveaux di-N-oxydes de quinoxaline. On obtient ces composés par réaction de di-N-oxydes de 2-méthyl-3-carboxamido-quinoxaline avec le formaldéhyde ou des agents libérant du formaldéhyde et avec des amines secondaires, en présence de solvants inertes. Les nouveaux composés de l'invention sont doués de propriétés antibactériennes. Ils peuvent être utilisés à ce titre en médecine humaine et en médecine vétérinaire. On peut en outre les utiliser comme additifs pour aliments.The invention relates to novel quinoxaline di-N-oxides. These compounds are obtained by reacting 2-methyl-3-carboxamido-quinoxaline di-N-oxides with formaldehyde or formaldehyde releasing agents and with secondary amines, in the presence of inert solvents. The new compounds of the invention are endowed with antibacterial properties. They can be used for this purpose in human medicine and in veterinary medicine. They can also be used as food additives.

FR7721702A 1976-07-14 1977-07-13 NEW QUINOXALINE DI-N-OXIDES, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCT CONTAINING THEM Withdrawn FR2358400A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19762631520 DE2631520A1 (en) 1976-07-14 1976-07-14 (2)-Methyl (3)-amino-methylcarbamoyl quinoxaline (1,4)-dioxides - for use as antibacterial agents
DE19762638732 DE2638732A1 (en) 1976-08-27 1976-08-27 (2)-Methyl (3)-amino-methylcarbamoyl quinoxaline (1,4)-dioxides - for use as antibacterial agents

Publications (1)

Publication Number Publication Date
FR2358400A1 true FR2358400A1 (en) 1978-02-10

Family

ID=25770692

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7721702A Withdrawn FR2358400A1 (en) 1976-07-14 1977-07-13 NEW QUINOXALINE DI-N-OXIDES, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCT CONTAINING THEM

Country Status (4)

Country Link
JP (1) JPS539780A (en)
FR (1) FR2358400A1 (en)
GB (1) GB1541993A (en)
NL (1) NL7707867A (en)

Also Published As

Publication number Publication date
GB1541993A (en) 1979-03-14
NL7707867A (en) 1978-01-17
JPS539780A (en) 1978-01-28

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Legal Events

Date Code Title Description
ST Notification of lapse