FR2356647A1 - Derives 3-aldehyde et 3-acetals de la 6,11-dihydro-dibenzo(b.e.)-thiepinne-11-one et procedes d'obtention - Google Patents

Derives 3-aldehyde et 3-acetals de la 6,11-dihydro-dibenzo(b.e.)-thiepinne-11-one et procedes d'obtention

Info

Publication number
FR2356647A1
FR2356647A1 FR7720211A FR7720211A FR2356647A1 FR 2356647 A1 FR2356647 A1 FR 2356647A1 FR 7720211 A FR7720211 A FR 7720211A FR 7720211 A FR7720211 A FR 7720211A FR 2356647 A1 FR2356647 A1 FR 2356647A1
Authority
FR
France
Prior art keywords
aldehyde
processes
thiepinne
dibenzo
acetals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7720211A
Other languages
English (en)
Other versions
FR2356647B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of FR2356647A1 publication Critical patent/FR2356647A1/fr
Application granted granted Critical
Publication of FR2356647B1 publication Critical patent/FR2356647B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/12—[b,e]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

L'invention concerne les dérivés 3-aldéhyde et 3-acétals de la 6,11 dihydrodibenzo-Øb.e.õ-thiépinne- 11 -one et leurs procédés d'obtention. Les composés de l'invention répondent aux formules :
FR7720211A 1976-07-01 1977-06-30 Derives 3-aldehyde et 3-acetals de la 6,11-dihydro-dibenzo(b.e.)-thiepinne-11-one et procedes d'obtention Granted FR2356647A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/701,780 US4066663A (en) 1976-07-01 1976-07-01 6,11-Dihydrodibenzo-[b. e.]-thiepin-11-one-3-aldehyde and 3-acetal derivatives

Publications (2)

Publication Number Publication Date
FR2356647A1 true FR2356647A1 (fr) 1978-01-27
FR2356647B1 FR2356647B1 (fr) 1979-07-20

Family

ID=24818648

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7720211A Granted FR2356647A1 (fr) 1976-07-01 1977-06-30 Derives 3-aldehyde et 3-acetals de la 6,11-dihydro-dibenzo(b.e.)-thiepinne-11-one et procedes d'obtention

Country Status (11)

Country Link
US (1) US4066663A (fr)
JP (1) JPS535182A (fr)
AU (1) AU2660577A (fr)
BE (1) BE856144A (fr)
DE (1) DE2729120A1 (fr)
ES (2) ES460297A1 (fr)
FR (1) FR2356647A1 (fr)
GB (1) GB1532205A (fr)
NL (1) NL7707136A (fr)
NZ (1) NZ184517A (fr)
ZA (1) ZA773933B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698873A1 (fr) * 1992-12-07 1994-06-10 Lipha Benzocycloheptènes, benzoxépines et benzothiépines activateurs des canaux potassiques, procédé de préparation, composition pharmaceutique les contenant.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO743186L (fr) * 1973-09-13 1975-04-07 Sandoz Ag

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698873A1 (fr) * 1992-12-07 1994-06-10 Lipha Benzocycloheptènes, benzoxépines et benzothiépines activateurs des canaux potassiques, procédé de préparation, composition pharmaceutique les contenant.
WO1994013658A2 (fr) * 1992-12-07 1994-06-23 Merck Patent Gmbh Benzocycloheptenes, benzoxepines et benzothiepines
WO1994013658A3 (fr) * 1992-12-07 1994-08-04 Merck Patent Gmbh Benzocycloheptenes, benzoxepines et benzothiepines

Also Published As

Publication number Publication date
FR2356647B1 (fr) 1979-07-20
ES469913A1 (es) 1978-12-16
ZA773933B (en) 1979-02-28
BE856144A (fr) 1977-12-27
AU2660577A (en) 1979-01-04
ES460297A1 (es) 1978-08-16
DE2729120A1 (de) 1978-01-12
GB1532205A (en) 1978-11-15
NL7707136A (nl) 1978-01-03
JPS535182A (en) 1978-01-18
NZ184517A (en) 1979-03-28
US4066663A (en) 1978-01-03

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