FR2350846A1 - Inhibiteurs peptidiques d'enzymes - Google Patents
Inhibiteurs peptidiques d'enzymesInfo
- Publication number
- FR2350846A1 FR2350846A1 FR7614601A FR7614601A FR2350846A1 FR 2350846 A1 FR2350846 A1 FR 2350846A1 FR 7614601 A FR7614601 A FR 7614601A FR 7614601 A FR7614601 A FR 7614601A FR 2350846 A1 FR2350846 A1 FR 2350846A1
- Authority
- FR
- France
- Prior art keywords
- inhibitors
- angiotensini
- nonapeptide
- amides
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 150000001408 amides Chemical class 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 230000001631 hypertensive effect Effects 0.000 title 1
- 102400000344 Angiotensin-1 Human genes 0.000 abstract 2
- 101800000734 Angiotensin-1 Proteins 0.000 abstract 2
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 2
- ORWYRWWVDCYOMK-HBZPZAIKSA-N angiotensin I Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC(C)C)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C1=CC=C(O)C=C1 ORWYRWWVDCYOMK-HBZPZAIKSA-N 0.000 abstract 2
- 108010072661 Angiotensin Amide Proteins 0.000 abstract 1
- 101800000733 Angiotensin-2 Proteins 0.000 abstract 1
- 102400000345 Angiotensin-2 Human genes 0.000 abstract 1
- 208000007530 Essential hypertension Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229950006323 angiotensin ii Drugs 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7614601A FR2350846A1 (fr) | 1976-05-14 | 1976-05-14 | Inhibiteurs peptidiques d'enzymes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7614601A FR2350846A1 (fr) | 1976-05-14 | 1976-05-14 | Inhibiteurs peptidiques d'enzymes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2350846A1 true FR2350846A1 (fr) | 1977-12-09 |
| FR2350846B1 FR2350846B1 (enExample) | 1978-10-20 |
Family
ID=9173164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7614601A Granted FR2350846A1 (fr) | 1976-05-14 | 1976-05-14 | Inhibiteurs peptidiques d'enzymes |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2350846A1 (enExample) |
-
1976
- 1976-05-14 FR FR7614601A patent/FR2350846A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2350846B1 (enExample) | 1978-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |