FR2332278A1 - Procede de transformation stereochimique des alcaloides du quinquina - Google Patents
Procede de transformation stereochimique des alcaloides du quinquinaInfo
- Publication number
- FR2332278A1 FR2332278A1 FR7535382A FR7535382A FR2332278A1 FR 2332278 A1 FR2332278 A1 FR 2332278A1 FR 7535382 A FR7535382 A FR 7535382A FR 7535382 A FR7535382 A FR 7535382A FR 2332278 A1 FR2332278 A1 FR 2332278A1
- Authority
- FR
- France
- Prior art keywords
- redn
- oxidn
- ketone
- isomerisation
- isopropanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000021513 Cinchona Nutrition 0.000 title abstract 2
- 241000157855 Cinchona Species 0.000 title abstract 2
- 229930013930 alkaloid Natural products 0.000 title abstract 2
- 150000002576 ketones Chemical class 0.000 title abstract 2
- 239000002904 solvent Substances 0.000 title abstract 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 title 2
- 238000006317 isomerization reaction Methods 0.000 title 1
- 150000004678 hydrides Chemical class 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7535382A FR2332278A1 (fr) | 1975-11-19 | 1975-11-19 | Procede de transformation stereochimique des alcaloides du quinquina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7535382A FR2332278A1 (fr) | 1975-11-19 | 1975-11-19 | Procede de transformation stereochimique des alcaloides du quinquina |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2332278A1 true FR2332278A1 (fr) | 1977-06-17 |
| FR2332278B1 FR2332278B1 (cg-RX-API-DMAC7.html) | 1978-05-19 |
Family
ID=9162615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7535382A Granted FR2332278A1 (fr) | 1975-11-19 | 1975-11-19 | Procede de transformation stereochimique des alcaloides du quinquina |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2332278A1 (cg-RX-API-DMAC7.html) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0000009A1 (fr) * | 1977-06-15 | 1978-12-20 | Devinter S.A. | Procédé d'oxydation de quinine en quininone et quinidinone. |
| EP0000302A1 (fr) * | 1977-06-15 | 1979-01-10 | Devinter S.A. | Nouveau procédé de préparation de la quinidine. |
| EP0790249A1 (de) * | 1996-02-07 | 1997-08-20 | Buchler GmbH | Enantiomerenreine Chinuklidinderivate und Verfahren zu ihrer Herstellung |
-
1975
- 1975-11-19 FR FR7535382A patent/FR2332278A1/fr active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0000009A1 (fr) * | 1977-06-15 | 1978-12-20 | Devinter S.A. | Procédé d'oxydation de quinine en quininone et quinidinone. |
| EP0000302A1 (fr) * | 1977-06-15 | 1979-01-10 | Devinter S.A. | Nouveau procédé de préparation de la quinidine. |
| EP0790249A1 (de) * | 1996-02-07 | 1997-08-20 | Buchler GmbH | Enantiomerenreine Chinuklidinderivate und Verfahren zu ihrer Herstellung |
| US5777122A (en) * | 1996-02-07 | 1998-07-07 | Buchler Gmbh | Enantiomerically pure quinuclidine derivatives and methods for their production and use |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2332278B1 (cg-RX-API-DMAC7.html) | 1978-05-19 |
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