FR2329280A1 - Nouveaux derives d'hydroxyanilino-hexahydro-2h-benzo(a)-quinolizines substituees en position 2 et medicament les contenant - Google Patents

Nouveaux derives d'hydroxyanilino-hexahydro-2h-benzo(a)-quinolizines substituees en position 2 et medicament les contenant

Info

Publication number
FR2329280A1
FR2329280A1 FR7632248A FR7632248A FR2329280A1 FR 2329280 A1 FR2329280 A1 FR 2329280A1 FR 7632248 A FR7632248 A FR 7632248A FR 7632248 A FR7632248 A FR 7632248A FR 2329280 A1 FR2329280 A1 FR 2329280A1
Authority
FR
France
Prior art keywords
quinolizines
hydroxyanilino
hexahydro
benzo
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7632248A
Other languages
English (en)
Other versions
FR2329280B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of FR2329280A1 publication Critical patent/FR2329280A1/fr
Application granted granted Critical
Publication of FR2329280B1 publication Critical patent/FR2329280B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C07D455/06—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7632248A 1975-10-30 1976-10-26 Nouveaux derives d'hydroxyanilino-hexahydro-2h-benzo(a)-quinolizines substituees en position 2 et medicament les contenant Granted FR2329280A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/627,063 US3995041A (en) 1975-10-30 1975-10-30 Derivatives of 2-substituted-hydroxyanilino-hexahydro-2H-benzo[α]quinolizines

Publications (2)

Publication Number Publication Date
FR2329280A1 true FR2329280A1 (fr) 1977-05-27
FR2329280B1 FR2329280B1 (fr) 1978-11-17

Family

ID=24513035

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7632248A Granted FR2329280A1 (fr) 1975-10-30 1976-10-26 Nouveaux derives d'hydroxyanilino-hexahydro-2h-benzo(a)-quinolizines substituees en position 2 et medicament les contenant

Country Status (7)

Country Link
US (1) US3995041A (fr)
JP (1) JPS5257196A (fr)
BE (1) BE847820A (fr)
FR (1) FR2329280A1 (fr)
GB (1) GB1532078A (fr)
NL (1) NL7611096A (fr)
ZA (1) ZA765403B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513824A (en) * 1975-05-22 1978-06-14 Wyeth John & Brother Ltd 1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizine derivative
US4230710A (en) * 1978-10-23 1980-10-28 Miles Laboratories, Inc. Amide derivatives of 2-substituted anilino-hexahydrobenzo[a]quinolizines, and methods of treating hypertension employing them
IE51467B1 (en) * 1980-08-28 1986-12-24 Wyeth John & Brother Ltd Benzoquinolizines
GR871701B (en) * 1986-11-07 1988-03-04 Oreal Method for preparing 5,6 - dihydrixyindol, and its 3 - alkylated derivative and intermediates
CA2728915A1 (fr) * 2008-06-24 2010-01-21 Valeant Pharmaceuticals International Derives de benzyloxy anilide utiles en tant que modulateurs du canal potassique

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634431A (en) * 1969-12-22 1972-01-11 Miles Lab Acylated and alkylated derivatives of 2-aminohexahydrobenzo(a)quinolizines
US3635986A (en) * 1969-12-22 1972-01-18 Miles Lab 2-substituted amino-hexahydrobenzo(a)quinolizines

Also Published As

Publication number Publication date
BE847820A (fr) 1977-02-14
AU1775176A (en) 1977-05-05
GB1532078A (en) 1978-11-15
FR2329280B1 (fr) 1978-11-17
JPS5257196A (en) 1977-05-11
ZA765403B (en) 1977-08-31
NL7611096A (nl) 1977-05-03
US3995041A (en) 1976-11-30

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Legal Events

Date Code Title Description
ST Notification of lapse