FR2325373A1 - Nouvelle oxazole dione substituee, procede de preparation et application comme medicament - Google Patents
Nouvelle oxazole dione substituee, procede de preparation et application comme medicamentInfo
- Publication number
- FR2325373A1 FR2325373A1 FR7529071A FR7529071A FR2325373A1 FR 2325373 A1 FR2325373 A1 FR 2325373A1 FR 7529071 A FR7529071 A FR 7529071A FR 7529071 A FR7529071 A FR 7529071A FR 2325373 A1 FR2325373 A1 FR 2325373A1
- Authority
- FR
- France
- Prior art keywords
- deriv
- oxazole
- antiandrogenic
- dione
- peripheral receptors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002280 anti-androgenic effect Effects 0.000 title abstract 2
- 230000002093 peripheral effect Effects 0.000 title abstract 2
- YCZPVAWKLUWQBP-UHFFFAOYSA-N 4-isocyanato-1-nitro-2-(trifluoromethyl)benzene Chemical compound [O-][N+](=O)C1=CC=C(N=C=O)C=C1C(F)(F)F YCZPVAWKLUWQBP-UHFFFAOYSA-N 0.000 abstract 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 208000003200 Adenoma Diseases 0.000 abstract 1
- 206010020112 Hirsutism Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 abstract 1
- 206010039792 Seborrhoea Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 239000003098 androgen Substances 0.000 abstract 1
- 229940030486 androgens Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- GFUIDHWFLMPAGY-UHFFFAOYSA-N ethyl 2-hydroxy-2-methylpropanoate Chemical compound CCOC(=O)C(C)(C)O GFUIDHWFLMPAGY-UHFFFAOYSA-N 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 210000002307 prostate Anatomy 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7529071A FR2325373A1 (fr) | 1975-09-23 | 1975-09-23 | Nouvelle oxazole dione substituee, procede de preparation et application comme medicament |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7529071A FR2325373A1 (fr) | 1975-09-23 | 1975-09-23 | Nouvelle oxazole dione substituee, procede de preparation et application comme medicament |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2325373A1 true FR2325373A1 (fr) | 1977-04-22 |
| FR2325373B1 FR2325373B1 (enrdf_load_stackoverflow) | 1979-09-14 |
Family
ID=9160321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7529071A Granted FR2325373A1 (fr) | 1975-09-23 | 1975-09-23 | Nouvelle oxazole dione substituee, procede de preparation et application comme medicament |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2325373A1 (enrdf_load_stackoverflow) |
-
1975
- 1975-09-23 FR FR7529071A patent/FR2325373A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2325373B1 (enrdf_load_stackoverflow) | 1979-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |