FR2315934A1 - PHARMACEUTICAL COMPOSITIONS BASED ON DIAZEPINE DERIVATIVES - Google Patents

PHARMACEUTICAL COMPOSITIONS BASED ON DIAZEPINE DERIVATIVES

Info

Publication number
FR2315934A1
FR2315934A1 FR7619601A FR7619601A FR2315934A1 FR 2315934 A1 FR2315934 A1 FR 2315934A1 FR 7619601 A FR7619601 A FR 7619601A FR 7619601 A FR7619601 A FR 7619601A FR 2315934 A1 FR2315934 A1 FR 2315934A1
Authority
FR
France
Prior art keywords
pharmaceutical compositions
compositions based
diazepine derivatives
diazepine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7619601A
Other languages
French (fr)
Other versions
FR2315934B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/592,708 external-priority patent/US4011319A/en
Priority claimed from US05/602,042 external-priority patent/US4052506A/en
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of FR2315934A1 publication Critical patent/FR2315934A1/en
Application granted granted Critical
Publication of FR2315934B1 publication Critical patent/FR2315934B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FR7619601A 1975-07-02 1976-06-28 PHARMACEUTICAL COMPOSITIONS BASED ON DIAZEPINE DERIVATIVES Granted FR2315934A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/592,708 US4011319A (en) 1975-07-02 1975-07-02 Pharmaceutical compositions and methods involving benzazepine derivatives
US05/602,042 US4052506A (en) 1975-08-05 1975-08-05 Pharmaceutical compositions and method of producing anti-parkinsonism activity

Publications (2)

Publication Number Publication Date
FR2315934A1 true FR2315934A1 (en) 1977-01-28
FR2315934B1 FR2315934B1 (en) 1978-11-17

Family

ID=27081519

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7619601A Granted FR2315934A1 (en) 1975-07-02 1976-06-28 PHARMACEUTICAL COMPOSITIONS BASED ON DIAZEPINE DERIVATIVES

Country Status (10)

Country Link
JP (1) JPS527981A (en)
AU (1) AU507272B2 (en)
CA (1) CA1079639A (en)
DE (1) DE2629887A1 (en)
FR (1) FR2315934A1 (en)
GB (1) GB1561305A (en)
IE (1) IE43920B1 (en)
IL (1) IL49931A (en)
LU (1) LU75269A1 (en)
NL (1) NL7607184A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378016A1 (en) * 1977-01-19 1978-08-18 Smithkline Corp 1-ALKYLTHIOPHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE SUBSTITUTES AND THEIR APPLICATION IN THERAPEUTICS
FR2400005A1 (en) * 1977-08-11 1979-03-09 Tanabe Seiyaku Co BENZYL ALCOHOL DERIVATIVES, THEIR MANUFACTURING PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
EP0002327A1 (en) * 1977-11-17 1979-06-13 Smithkline Beckman Corporation Pharmacologically active 6-lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, method of preparing them and intermediates

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA777444B (en) * 1977-01-19 1978-10-25 Smithkline Corp Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines having dopaminergic activity
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
EP0022330B1 (en) * 1979-07-10 1983-12-21 Smithkline Beckman Corporation Synergistic antihypertensive compositions
EP0103830A3 (en) * 1982-09-22 1985-07-31 Bayer Ag Phenylethylemine derivatires as growth stimulators
US5068326A (en) * 1989-04-03 1991-11-26 Kung Hank F Dopamine receptor ligands and imaging agents
GB9903671D0 (en) * 1999-02-17 1999-04-14 Cenes Ltd Dopamine D-1 receptor agonist compounds
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
WO2005035504A2 (en) * 2003-05-22 2005-04-21 Schering Corporation 5-h -benzo [d] naphth [2, 1-b] azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1118688A (en) * 1967-02-17 1968-07-03 Scherico Ltd Novel benzazepines and process for making same
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
US3609138A (en) * 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
GB1118688A (en) * 1967-02-17 1968-07-03 Scherico Ltd Novel benzazepines and process for making same
US3609138A (en) * 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378016A1 (en) * 1977-01-19 1978-08-18 Smithkline Corp 1-ALKYLTHIOPHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE SUBSTITUTES AND THEIR APPLICATION IN THERAPEUTICS
FR2400005A1 (en) * 1977-08-11 1979-03-09 Tanabe Seiyaku Co BENZYL ALCOHOL DERIVATIVES, THEIR MANUFACTURING PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
US4490392A (en) * 1977-08-11 1984-12-25 Tanabe Seiyaku Co., Ltd. Benzylalcohol derivative and process for preparing
EP0002327A1 (en) * 1977-11-17 1979-06-13 Smithkline Beckman Corporation Pharmacologically active 6-lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, method of preparing them and intermediates
FR2422641A1 (en) * 1977-11-17 1979-11-09 Smithkline Corp 7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES
EP0026505A1 (en) * 1977-11-17 1981-04-08 Smithkline Beckman Corporation 7,8-Substituted-1-phenyl-2,3,4,5-tetrahydro-1-H-3-benzazepines

Also Published As

Publication number Publication date
IL49931A0 (en) 1976-08-31
CA1079639A (en) 1980-06-17
AU507272B2 (en) 1980-02-07
LU75269A1 (en) 1977-02-18
IE43920L (en) 1977-01-02
IE43920B1 (en) 1981-07-01
GB1561305A (en) 1980-02-20
FR2315934B1 (en) 1978-11-17
AU1554076A (en) 1978-01-05
DE2629887A1 (en) 1977-01-20
IL49931A (en) 1981-12-31
JPS527981A (en) 1977-01-21
NL7607184A (en) 1977-01-04

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Legal Events

Date Code Title Description
CD Change of name or company name
ST Notification of lapse