FR2313914A1 - STABLE INSULIN PREPARATION FOR NASAL ADMINISTRATION - Google Patents
STABLE INSULIN PREPARATION FOR NASAL ADMINISTRATIONInfo
- Publication number
- FR2313914A1 FR2313914A1 FR7614706A FR7614706A FR2313914A1 FR 2313914 A1 FR2313914 A1 FR 2313914A1 FR 7614706 A FR7614706 A FR 7614706A FR 7614706 A FR7614706 A FR 7614706A FR 2313914 A1 FR2313914 A1 FR 2313914A1
- Authority
- FR
- France
- Prior art keywords
- nasal administration
- insulin preparation
- stable insulin
- stable
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2535175A GB1554157A (en) | 1975-06-13 | 1975-06-13 | Stable insulin preparation for intra nasal administration |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2313914A1 true FR2313914A1 (en) | 1977-01-07 |
FR2313914B1 FR2313914B1 (en) | 1979-04-13 |
Family
ID=10226264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7614706A Granted FR2313914A1 (en) | 1975-06-13 | 1976-05-14 | STABLE INSULIN PREPARATION FOR NASAL ADMINISTRATION |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS51148013A (en) |
BE (1) | BE841870A (en) |
DE (1) | DE2620483A1 (en) |
FR (1) | FR2313914A1 (en) |
GB (1) | GB1554157A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0183527A2 (en) * | 1984-11-26 | 1986-06-04 | Yamanouchi Pharmaceutical Co. Ltd. | Absorbable calcitonin medicament |
EP0200383A2 (en) * | 1985-04-15 | 1986-11-05 | Eli Lilly And Company | An improved method for administering insulin |
EP0242643A2 (en) * | 1986-04-23 | 1987-10-28 | Fisons Corporation | Nasal administration of drugs |
EP0351651A2 (en) * | 1988-07-21 | 1990-01-24 | F. Hoffmann-La Roche Ag | Insulin preparation |
ITRM20110390A1 (en) * | 2011-07-21 | 2013-01-22 | Eramo Alessandra D | PRODUCT TO STIMULATE THE ENDOGENOUS PRODUCTION OF INFLAMMATION MEDIATORS. |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4783441A (en) * | 1979-04-30 | 1988-11-08 | Hoechst Aktiengesellschaft | Aqueous protein solutions stable to denaturation |
EP0018609B1 (en) * | 1979-04-30 | 1983-09-21 | Hoechst Aktiengesellschaft | Aqueous solutions of proteins stable against denaturization, process for their manufacture, and their utilization |
DE2917535C2 (en) * | 1979-04-30 | 1986-10-30 | Hoechst Ag, 6230 Frankfurt | Insulin solutions resistant to denaturation |
JPS58501125A (en) * | 1981-07-17 | 1983-07-14 | ノルデイスク・インスリンラボラトリウム | Stable aqueous therapeutic insulin preparation and method for producing the same |
DE3443877A1 (en) * | 1984-06-09 | 1985-12-12 | Hoechst Ag | Insulin preparations, process for their preparation, and their use |
DK179286D0 (en) * | 1986-04-18 | 1986-04-18 | Nordisk Gentofte | INSULIN PREPARATION |
WO1991016929A1 (en) * | 1990-05-10 | 1991-11-14 | Novo Nordisk A/S | A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols |
US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
US6932962B1 (en) | 1994-12-22 | 2005-08-23 | Astrazeneca Ab | Aerosol drug formulations containing hydrofluoroalkanes and alkyl saccharides |
DE10227232A1 (en) * | 2002-06-18 | 2004-01-15 | Aventis Pharma Deutschland Gmbh | Sour insulin preparations with improved stability |
NZ547587A (en) * | 2003-12-08 | 2009-09-25 | Cpex Pharmaceuticals Inc | Pharmaceutical compositions and methods for insulin treatment |
US7851419B2 (en) * | 2005-09-12 | 2010-12-14 | Nawaz Ahmad | Substantially anhydrous sprayable personal lubricant |
PT2349324T (en) | 2008-10-17 | 2017-12-06 | Sanofi Aventis Deutschland | Combination of an insulin and a glp-1 agonist |
PL3345593T3 (en) | 2009-11-13 | 2024-04-08 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical composition comprising despro36exendin-4(1-39)-lys6-nh2 and methionine |
PE20121362A1 (en) | 2009-11-13 | 2012-10-17 | Sanofi Aventis Deutschland | PHARMACEUTICAL COMPOSITION INCLUDING DESPRO36EXENDIN-4 (1-39) -LYS6-NH2, INSULIN GLY (A21) -ARG (B31) -ARG (B32) AND METHIONINE |
WO2012028172A1 (en) | 2010-08-30 | 2012-03-08 | Sanofi-Aventis Deutschland Gmbh | Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2 |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
AU2012300978B2 (en) | 2011-08-29 | 2017-04-27 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for use in glycemic control in diabetes type 2 patients |
AR087744A1 (en) | 2011-09-01 | 2014-04-16 | Sanofi Aventis Deutschland | PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OF A NEURODEGENERATIVE DISEASE |
EP3030294B1 (en) * | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
EP3229828B1 (en) | 2014-12-12 | 2023-04-05 | Sanofi-Aventis Deutschland GmbH | Insulin glargine/lixisenatide fixed ratio formulation |
TWI748945B (en) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | Treatment type 2 diabetes mellitus patients |
TW201705975A (en) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | Treatment of type 2 diabetes mellitus patients |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL62232C (en) * | 1900-01-01 | |||
US3096249A (en) * | 1960-05-10 | 1963-07-02 | Samuel J Prigal | Emulsion composition |
-
1975
- 1975-06-13 GB GB2535175A patent/GB1554157A/en not_active Expired
-
1976
- 1976-05-08 DE DE19762620483 patent/DE2620483A1/en not_active Withdrawn
- 1976-05-13 JP JP5493176A patent/JPS51148013A/en active Pending
- 1976-05-14 FR FR7614706A patent/FR2313914A1/en active Granted
- 1976-05-14 BE BE167069A patent/BE841870A/en not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL62232C (en) * | 1900-01-01 | |||
US3096249A (en) * | 1960-05-10 | 1963-07-02 | Samuel J Prigal | Emulsion composition |
Non-Patent Citations (1)
Title |
---|
CHEMICAL ABSTRACTS, Vol. 83, No. 22, 1ER DECEMBRE 1975, COLUMBUS, OHIO, U.S.A.: L. CITRONYL, "INSULIN PREPARATIONS TO BE ABSORBED FROM MUCOUS MEMBRANES", CITE & HU-TELJES NO. 9492, 28 MARS 1975. * |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0183527A2 (en) * | 1984-11-26 | 1986-06-04 | Yamanouchi Pharmaceutical Co. Ltd. | Absorbable calcitonin medicament |
EP0183527A3 (en) * | 1984-11-26 | 1987-09-23 | Yamanouchi Pharmaceutical Co. Ltd. | Absorbable calcitonin medicament |
EP0200383A2 (en) * | 1985-04-15 | 1986-11-05 | Eli Lilly And Company | An improved method for administering insulin |
EP0200383A3 (en) * | 1985-04-15 | 1987-09-02 | Eli Lilly And Company | An improved method for administering insulin |
EP0242643A2 (en) * | 1986-04-23 | 1987-10-28 | Fisons Corporation | Nasal administration of drugs |
EP0242643A3 (en) * | 1986-04-23 | 1988-04-06 | Delaware Chemicals Corporation | Nasal administration of drugs |
EP0351651A2 (en) * | 1988-07-21 | 1990-01-24 | F. Hoffmann-La Roche Ag | Insulin preparation |
EP0351651A3 (en) * | 1988-07-21 | 1990-10-10 | F. Hoffmann-La Roche Ag | Insulin preparation |
ITRM20110390A1 (en) * | 2011-07-21 | 2013-01-22 | Eramo Alessandra D | PRODUCT TO STIMULATE THE ENDOGENOUS PRODUCTION OF INFLAMMATION MEDIATORS. |
WO2013011536A1 (en) * | 2011-07-21 | 2013-01-24 | Fabrizio Salvinelli | Intranasal administration of agents with pro-inflammatory activity for the therapy of neurological disorders |
US9629969B2 (en) | 2011-07-21 | 2017-04-25 | Fabrizio Salvinelli | Intranasal administration of agents with pro-inflammatory activity for the therapy of neurological disorders |
Also Published As
Publication number | Publication date |
---|---|
BE841870A (en) | 1976-11-16 |
GB1554157A (en) | 1979-10-17 |
FR2313914B1 (en) | 1979-04-13 |
JPS51148013A (en) | 1976-12-18 |
DE2620483A1 (en) | 1976-12-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |