FR2313914A1 - STABLE INSULIN PREPARATION FOR NASAL ADMINISTRATION - Google Patents

STABLE INSULIN PREPARATION FOR NASAL ADMINISTRATION

Info

Publication number
FR2313914A1
FR2313914A1 FR7614706A FR7614706A FR2313914A1 FR 2313914 A1 FR2313914 A1 FR 2313914A1 FR 7614706 A FR7614706 A FR 7614706A FR 7614706 A FR7614706 A FR 7614706A FR 2313914 A1 FR2313914 A1 FR 2313914A1
Authority
FR
France
Prior art keywords
nasal administration
insulin preparation
stable insulin
stable
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7614706A
Other languages
French (fr)
Other versions
FR2313914B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FR2313914A1 publication Critical patent/FR2313914A1/en
Application granted granted Critical
Publication of FR2313914B1 publication Critical patent/FR2313914B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR7614706A 1975-06-13 1976-05-14 STABLE INSULIN PREPARATION FOR NASAL ADMINISTRATION Granted FR2313914A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2535175A GB1554157A (en) 1975-06-13 1975-06-13 Stable insulin preparation for intra nasal administration

Publications (2)

Publication Number Publication Date
FR2313914A1 true FR2313914A1 (en) 1977-01-07
FR2313914B1 FR2313914B1 (en) 1979-04-13

Family

ID=10226264

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7614706A Granted FR2313914A1 (en) 1975-06-13 1976-05-14 STABLE INSULIN PREPARATION FOR NASAL ADMINISTRATION

Country Status (5)

Country Link
JP (1) JPS51148013A (en)
BE (1) BE841870A (en)
DE (1) DE2620483A1 (en)
FR (1) FR2313914A1 (en)
GB (1) GB1554157A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0183527A2 (en) * 1984-11-26 1986-06-04 Yamanouchi Pharmaceutical Co. Ltd. Absorbable calcitonin medicament
EP0200383A2 (en) * 1985-04-15 1986-11-05 Eli Lilly And Company An improved method for administering insulin
EP0242643A2 (en) * 1986-04-23 1987-10-28 Fisons Corporation Nasal administration of drugs
EP0351651A2 (en) * 1988-07-21 1990-01-24 F. Hoffmann-La Roche Ag Insulin preparation
ITRM20110390A1 (en) * 2011-07-21 2013-01-22 Eramo Alessandra D PRODUCT TO STIMULATE THE ENDOGENOUS PRODUCTION OF INFLAMMATION MEDIATORS.

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783441A (en) * 1979-04-30 1988-11-08 Hoechst Aktiengesellschaft Aqueous protein solutions stable to denaturation
DE3064888D1 (en) * 1979-04-30 1983-10-27 Hoechst Ag Aqueous solutions of proteins stable against denaturization, process for their manufacture, and their utilization
DE2917535C2 (en) * 1979-04-30 1986-10-30 Hoechst Ag, 6230 Frankfurt Insulin solutions resistant to denaturation
WO1983000288A1 (en) * 1981-07-17 1983-02-03 Balschmidt, Per A stable aqueous, therapeutic insulin preparation and a process for preparing it
DE3443877A1 (en) * 1984-06-09 1985-12-12 Hoechst Ag Insulin preparations, process for their preparation, and their use
DK179286D0 (en) * 1986-04-18 1986-04-18 Nordisk Gentofte INSULIN PREPARATION
EP0532546B1 (en) * 1990-05-10 1998-03-18 Bechgaard International Research And Development A/S A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols
ATE236617T1 (en) 1994-12-22 2003-04-15 Astrazeneca Ab AEROSOL MEDICINAL FORMULATIONS
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
DE10227232A1 (en) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Sour insulin preparations with improved stability
EP1706128B1 (en) * 2003-12-08 2010-07-21 CPEX Pharmaceuticals, Inc. Pharmaceutical compositions and methods for insulin treatment
US7851419B2 (en) * 2005-09-12 2010-12-14 Nawaz Ahmad Substantially anhydrous sprayable personal lubricant
KR101820024B1 (en) 2008-10-17 2018-01-18 사노피-아벤티스 도이칠란트 게엠베하 Combination of an insulin and a GLP-1 agonist
HUE037735T2 (en) 2009-11-13 2018-09-28 Sanofi Aventis Deutschland PHARMACEUTICAL COMPOSITION COMPRISING desPro36Exendin-4(1-39)-Lys6-NH2 AND METHIONINE
ES2534191T3 (en) 2009-11-13 2015-04-20 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist, an insulin and methionine
BR112013004756B1 (en) 2010-08-30 2020-04-28 Sanofi Aventis Deutschland use of ave0010 for the manufacture of a medication for the treatment of type 2 diabetes mellitus
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
RU2650616C2 (en) 2011-08-29 2018-04-16 Санофи-Авентис Дойчланд Гмбх Pharmaceutical combination for use in glycemic control in patients with type 2 diabetes mellitus
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
WO2015021064A1 (en) * 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
JP6970615B2 (en) 2014-12-12 2021-11-24 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Insulin glargine / lixisenatide fixed ratio prescription
TWI748945B (en) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 Treatment type 2 diabetes mellitus patients
TW201705975A (en) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 Treatment of type 2 diabetes mellitus patients

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL62232C (en) * 1900-01-01
US3096249A (en) * 1960-05-10 1963-07-02 Samuel J Prigal Emulsion composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL62232C (en) * 1900-01-01
US3096249A (en) * 1960-05-10 1963-07-02 Samuel J Prigal Emulsion composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Vol. 83, No. 22, 1ER DECEMBRE 1975, COLUMBUS, OHIO, U.S.A.: L. CITRONYL, "INSULIN PREPARATIONS TO BE ABSORBED FROM MUCOUS MEMBRANES", CITE & HU-TELJES NO. 9492, 28 MARS 1975. *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0183527A2 (en) * 1984-11-26 1986-06-04 Yamanouchi Pharmaceutical Co. Ltd. Absorbable calcitonin medicament
EP0183527A3 (en) * 1984-11-26 1987-09-23 Yamanouchi Pharmaceutical Co. Ltd. Absorbable calcitonin medicament
EP0200383A2 (en) * 1985-04-15 1986-11-05 Eli Lilly And Company An improved method for administering insulin
EP0200383A3 (en) * 1985-04-15 1987-09-02 Eli Lilly And Company An improved method for administering insulin
EP0242643A2 (en) * 1986-04-23 1987-10-28 Fisons Corporation Nasal administration of drugs
EP0242643A3 (en) * 1986-04-23 1988-04-06 Delaware Chemicals Corporation Nasal administration of drugs
EP0351651A2 (en) * 1988-07-21 1990-01-24 F. Hoffmann-La Roche Ag Insulin preparation
EP0351651A3 (en) * 1988-07-21 1990-10-10 F. Hoffmann-La Roche Ag Insulin preparation
ITRM20110390A1 (en) * 2011-07-21 2013-01-22 Eramo Alessandra D PRODUCT TO STIMULATE THE ENDOGENOUS PRODUCTION OF INFLAMMATION MEDIATORS.
WO2013011536A1 (en) * 2011-07-21 2013-01-24 Fabrizio Salvinelli Intranasal administration of agents with pro-inflammatory activity for the therapy of neurological disorders
US9629969B2 (en) 2011-07-21 2017-04-25 Fabrizio Salvinelli Intranasal administration of agents with pro-inflammatory activity for the therapy of neurological disorders

Also Published As

Publication number Publication date
BE841870A (en) 1976-11-16
DE2620483A1 (en) 1976-12-23
FR2313914B1 (en) 1979-04-13
GB1554157A (en) 1979-10-17
JPS51148013A (en) 1976-12-18

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Legal Events

Date Code Title Description
ST Notification of lapse