FR22C1045I2 - PROTEIN-POLYMER CONJUGATES - Google Patents

PROTEIN-POLYMER CONJUGATES

Info

Publication number
FR22C1045I2
FR22C1045I2 FR22C1045C FR22C1045C FR22C1045I2 FR 22C1045 I2 FR22C1045 I2 FR 22C1045I2 FR 22C1045 C FR22C1045 C FR 22C1045C FR 22C1045 C FR22C1045 C FR 22C1045C FR 22C1045 I2 FR22C1045 I2 FR 22C1045I2
Authority
FR
France
Prior art keywords
protein
polymer conjugates
conjugates
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR22C1045C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PharmaEssentia Corp
Original Assignee
PharmaEssentia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40351178&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR22C1045(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PharmaEssentia Corp filed Critical PharmaEssentia Corp
Publication of FR22C1045I1 publication Critical patent/FR22C1045I1/en
Application granted granted Critical
Publication of FR22C1045I2 publication Critical patent/FR22C1045I2/en
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
FR22C1045C 2007-08-16 2022-08-26 PROTEIN-POLYMER CONJUGATES Active FR22C1045I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95627307P 2007-08-16 2007-08-16
PCT/US2008/073290 WO2009023826A1 (en) 2007-08-16 2008-08-15 Protein-polymer conjugates

Publications (2)

Publication Number Publication Date
FR22C1045I1 FR22C1045I1 (en) 2022-10-14
FR22C1045I2 true FR22C1045I2 (en) 2023-12-29

Family

ID=40351178

Family Applications (1)

Application Number Title Priority Date Filing Date
FR22C1045C Active FR22C1045I2 (en) 2007-08-16 2022-08-26 PROTEIN-POLYMER CONJUGATES

Country Status (30)

Country Link
US (1) US8143214B2 (en)
EP (2) EP4129343A1 (en)
JP (1) JP5613050B2 (en)
KR (1) KR101588465B1 (en)
CN (1) CN101367872B (en)
AR (1) AR067964A1 (en)
AU (1) AU2008286742B2 (en)
BR (1) BRPI0814482B8 (en)
CA (1) CA2696478C (en)
CL (1) CL2008002399A1 (en)
CY (1) CY1125751T1 (en)
DK (1) DK2205281T3 (en)
EA (1) EA018111B1 (en)
ES (1) ES2924727T3 (en)
FR (1) FR22C1045I2 (en)
HR (1) HRP20220937T3 (en)
HU (2) HUE059551T2 (en)
LT (1) LT2205281T (en)
MX (1) MX2010001750A (en)
MY (1) MY149148A (en)
NL (1) NL301195I2 (en)
NO (1) NO2022038I1 (en)
NZ (1) NZ583831A (en)
PL (1) PL2205281T3 (en)
PT (1) PT2205281T (en)
SI (1) SI2205281T1 (en)
TW (1) TWI381851B (en)
UA (1) UA103158C2 (en)
WO (1) WO2009023826A1 (en)
ZA (1) ZA201001777B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5639585B2 (en) * 2008-07-31 2014-12-10 ファーマエッセンティア コーポレイション Peptide-polymer conjugate
UA109646C2 (en) * 2009-12-10 2015-09-25 THERAPEUTIC APPLICATION OF POLYMER PROTEIN CONJUGATES
KR20230079520A (en) 2014-11-06 2023-06-07 파마에센시아 코퍼레이션 Dosage Regimen for PEGylated Interferon
CN112433048A (en) * 2020-11-17 2021-03-02 深圳上泰生物工程有限公司 Kit for chemiluminescence immunoassay, and preparation method and application thereof

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR850004274A (en) 1983-12-13 1985-07-11 원본미기재 Method for preparing erythropoietin
US5643575A (en) * 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
US5919455A (en) * 1993-10-27 1999-07-06 Enzon, Inc. Non-antigenic branched polymer conjugates
US5951974A (en) * 1993-11-10 1999-09-14 Enzon, Inc. Interferon polymer conjugates
US5824784A (en) * 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
US5932462A (en) * 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
TW517067B (en) * 1996-05-31 2003-01-11 Hoffmann La Roche Interferon conjugates
BR0013638A (en) * 1999-08-27 2002-05-14 Maxygen Aps New interferon beta-like molecules
WO2001036001A2 (en) * 1999-11-12 2001-05-25 Maxygen Holdings Ltd Interferon gamma conjugates
US7125843B2 (en) * 2001-10-19 2006-10-24 Neose Technologies, Inc. Glycoconjugates including more than one peptide
US20030171285A1 (en) * 2001-11-20 2003-09-11 Finn Rory F. Chemically-modified human growth hormone conjugates
KR20070072924A (en) * 2001-11-20 2007-07-06 파마시아 코포레이션 Chemically-modified human growth hormone conjugates
EA009783B1 (en) * 2002-01-18 2008-04-28 Байоджен Айдек Ма Инк. Polyalkylene glycolhaving a moiety for conjugation of a biologically active compound
US7345150B2 (en) * 2002-03-26 2008-03-18 Medical University Of Toledo Albumin-based colloid composition having at least one protected thiol region, methods of making, and methods of use
UA80838C2 (en) 2002-09-09 2007-11-12 Water-soluble polymer alkanals
ES2725808T3 (en) * 2003-05-23 2019-09-27 Nektar Therapeutics PEG derivatives containing two PEG chains
EP1694347B1 (en) * 2003-11-24 2013-11-20 BioGeneriX AG Glycopegylated erythropoietin
MX2007002441A (en) 2004-08-31 2007-05-04 Pharmacia & Upjohn Co Llc Glycerol branched polyethylene glycol human growth hormone conjugates, process for their preparation, and methods of use thereof.
US7365127B2 (en) * 2005-02-04 2008-04-29 Enzon Pharmaceuticals, Inc. Process for the preparation of polymer conjugates
EP1869079A2 (en) * 2005-03-11 2007-12-26 Siegfried Ltd. Di-polymer protein conjugates and processes for their preparation
WO2006094530A1 (en) * 2005-03-11 2006-09-14 Siegfried Ltd. Di-polymer protein conjugates and processes for their preparation
CN101002944B (en) 2006-01-17 2012-07-25 中国科学院过程工程研究所 Conjugate of branched chair polymacrogol-interferon, and its preparing method
CN101104078B (en) 2006-07-11 2011-11-02 北京美倍他药物研究有限公司 Polypeptide and protein medicine polyethylene coupling compound
CN101108895B (en) 2006-07-19 2011-10-26 北京键凯科技有限公司 Polyglycol ethanal derivant and combo of medicament and the same
CN1966547B (en) 2006-11-06 2011-11-09 中国药科大学 Double-chain structured polyethylene glycol derivative preparation and its combination with pharmaceutical molecule
CN1970572A (en) 2006-12-21 2007-05-30 北京三元基因工程有限公司 Interferon alpha mutant and its polyethylene glycol derivative
US8597635B2 (en) 2007-09-04 2013-12-03 Biosteed Gene Expression Tech. Co., Ltd. Interferon alpha-2B modified by polyethylene glycol and methods of preparation thereof
KR101483814B1 (en) 2007-09-04 2015-01-16 바이오스티드 진 익스프레션 테크. 컴파니 리미티드 Interferon alpha 2a modified by polyethylene glycol, its synthesis process and application
CN101491682A (en) 2008-04-30 2009-07-29 北京凯正生物工程发展有限责任公司 PEG-IFN omega conjugate and preparation technique thereof
CN101671390B (en) 2008-09-10 2012-10-03 海南四环心脑血管药物研究院有限公司 Human interferon alpha derivatives and preparation and use of pegylated products thereof
CN101514229B (en) 2009-04-03 2012-05-09 海南四环心脑血管药物研究院有限公司 Human interferon alpha derivative and polyethylene glycol modified substance thereof

Also Published As

Publication number Publication date
MY149148A (en) 2013-07-15
TWI381851B (en) 2013-01-11
BRPI0814482B8 (en) 2021-05-25
CY1125751T1 (en) 2023-06-09
EA018111B1 (en) 2013-05-30
KR101588465B1 (en) 2016-01-25
MX2010001750A (en) 2010-06-01
AR067964A1 (en) 2009-10-28
JP5613050B2 (en) 2014-10-22
CA2696478C (en) 2018-10-09
US8143214B2 (en) 2012-03-27
DK2205281T3 (en) 2022-08-15
JP2010536788A (en) 2010-12-02
NL301195I2 (en) 2023-03-02
AU2008286742A1 (en) 2009-02-19
ZA201001777B (en) 2010-12-29
EP2205281B1 (en) 2022-06-29
PT2205281T (en) 2022-08-02
BRPI0814482A2 (en) 2015-02-03
UA103158C2 (en) 2013-09-25
ES2924727T3 (en) 2022-10-10
AU2008286742B2 (en) 2014-05-29
US20090053177A1 (en) 2009-02-26
EA201070282A1 (en) 2010-08-30
NZ583831A (en) 2012-06-29
NL301195I1 (en) 2022-08-31
CA2696478A1 (en) 2009-02-19
HRP20220937T3 (en) 2022-09-30
LT2205281T (en) 2022-09-26
CN101367872A (en) 2009-02-18
EP2205281A4 (en) 2014-10-08
TW200916116A (en) 2009-04-16
EP2205281A1 (en) 2010-07-14
HUS2200039I1 (en) 2022-09-28
EP4129343A1 (en) 2023-02-08
WO2009023826A1 (en) 2009-02-19
BRPI0814482B1 (en) 2021-02-02
FR22C1045I1 (en) 2022-10-14
CL2008002399A1 (en) 2009-01-02
KR20100076945A (en) 2010-07-06
PL2205281T3 (en) 2022-12-12
HUE059551T2 (en) 2022-11-28
SI2205281T1 (en) 2022-11-30
NO2022038I1 (en) 2022-09-02
CN101367872B (en) 2013-11-20

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