FR2297043A1 - NEW AMID DERIVATIVES OF VINBLASTINE, LEUROSIDINE, LEUROCRISTINE AND RELATED DIMERAL ALKALOIDS - Google Patents

NEW AMID DERIVATIVES OF VINBLASTINE, LEUROSIDINE, LEUROCRISTINE AND RELATED DIMERAL ALKALOIDS

Info

Publication number
FR2297043A1
FR2297043A1 FR7600519A FR7600519A FR2297043A1 FR 2297043 A1 FR2297043 A1 FR 2297043A1 FR 7600519 A FR7600519 A FR 7600519A FR 7600519 A FR7600519 A FR 7600519A FR 2297043 A1 FR2297043 A1 FR 2297043A1
Authority
FR
France
Prior art keywords
dimeral
leurocristine
leurosidine
alkaloids
vinblastine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7600519A
Other languages
French (fr)
Other versions
FR2297043B1 (en
Inventor
George Joseph Cullinan
Koert Gerzon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2297043A1 publication Critical patent/FR2297043A1/en
Application granted granted Critical
Publication of FR2297043B1 publication Critical patent/FR2297043B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7600519A 1975-01-09 1976-01-09 NEW AMID DERIVATIVES OF VINBLASTINE, LEUROSIDINE, LEUROCRISTINE AND RELATED DIMERAL ALKALOIDS Granted FR2297043A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53968175A 1975-01-09 1975-01-09

Publications (2)

Publication Number Publication Date
FR2297043A1 true FR2297043A1 (en) 1976-08-06
FR2297043B1 FR2297043B1 (en) 1978-08-11

Family

ID=24152219

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7600519A Granted FR2297043A1 (en) 1975-01-09 1976-01-09 NEW AMID DERIVATIVES OF VINBLASTINE, LEUROSIDINE, LEUROCRISTINE AND RELATED DIMERAL ALKALOIDS

Country Status (13)

Country Link
JP (1) JPS5195100A (en)
BE (1) BE837390A (en)
CA (1) CA1067073A (en)
CH (1) CH624962A5 (en)
CS (1) CS199615B2 (en)
DE (1) DE2558027A1 (en)
FR (1) FR2297043A1 (en)
GB (1) GB1538921A (en)
HU (1) HU176226B (en)
IE (1) IE42385B1 (en)
IL (1) IL48685A (en)
NL (1) NL7515253A (en)
PH (1) PH17563A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378032A1 (en) * 1977-01-19 1978-08-18 Lilly Co Eli 4'-DESOXYVINCRISTINE AND RELATED COMPOUNDS, AND THEIR USE AS MEDICINAL PRODUCTS
FR2438052A1 (en) * 1978-05-15 1980-04-30 Lilly Co Eli NOVEL PROCESS FOR THE PREPARATION OF BRIDGE DIMERES OF CATHARANTHUS ALKALOIDS AND INTERMEDIATE COMPOUNDS
FR2438659A1 (en) * 1978-10-10 1980-05-09 Lilly Co Eli PROCESS FOR THE PREPARATION OF VINDESIN SULFATE

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR69783B (en) * 1976-09-08 1982-07-07 Lilly Co Eli
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4191688A (en) 1977-08-08 1980-03-04 Eli Lilly And Company Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
US4195022A (en) 1978-03-27 1980-03-25 Eli Lilly And Company 4-Desacetoxy-4α-hydroxyvinblastine and related compounds
US4166810A (en) * 1978-04-20 1979-09-04 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
LU83822A1 (en) * 1981-12-08 1983-09-01 Omnichem Sa N- (VINBLASTINOYL-23) DERIVATIVES OF AMINO ACIDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (en) * 1973-04-02 1975-11-12 Lilly Co Eli PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378032A1 (en) * 1977-01-19 1978-08-18 Lilly Co Eli 4'-DESOXYVINCRISTINE AND RELATED COMPOUNDS, AND THEIR USE AS MEDICINAL PRODUCTS
FR2438052A1 (en) * 1978-05-15 1980-04-30 Lilly Co Eli NOVEL PROCESS FOR THE PREPARATION OF BRIDGE DIMERES OF CATHARANTHUS ALKALOIDS AND INTERMEDIATE COMPOUNDS
EP0032756A2 (en) * 1978-05-15 1981-07-29 Eli Lilly And Company Intermediates used in the preparation of bridged catharanthus alkaloid dimers
EP0033981A2 (en) * 1978-05-15 1981-08-19 Eli Lilly And Company Preparation of bridged catharanthus alkaloid dimers
EP0033981A3 (en) * 1978-05-15 1981-09-09 Eli Lilly And Company Preparation of bridged catharanthus alkaloid dimers
EP0032756A3 (en) * 1978-05-15 1981-09-09 Eli Lilly And Company Intermediates used in the preparation of bridged catharanthus alkaloid dimers
FR2438659A1 (en) * 1978-10-10 1980-05-09 Lilly Co Eli PROCESS FOR THE PREPARATION OF VINDESIN SULFATE

Also Published As

Publication number Publication date
IL48685A0 (en) 1976-02-29
HU176226B (en) 1981-01-28
IL48685A (en) 1980-03-31
DE2558027A1 (en) 1976-07-15
CH624962A5 (en) 1981-08-31
IE42385B1 (en) 1980-07-30
BE837390A (en) 1976-07-08
CS199615B2 (en) 1980-07-31
FR2297043B1 (en) 1978-08-11
PH17563A (en) 1984-10-01
GB1538921A (en) 1979-01-24
NL7515253A (en) 1976-07-13
CA1067073A (en) 1979-11-27
IE42385L (en) 1976-07-09
JPS5195100A (en) 1976-08-20

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