FR2293947A1 - Antimicrobial sutures, dressings, prostheses - coated with an elastomeric polyurethane with pendant anionic or cationic antimicrobial cpds - Google Patents

Antimicrobial sutures, dressings, prostheses - coated with an elastomeric polyurethane with pendant anionic or cationic antimicrobial cpds

Info

Publication number
FR2293947A1
FR2293947A1 FR7537783A FR7537783A FR2293947A1 FR 2293947 A1 FR2293947 A1 FR 2293947A1 FR 7537783 A FR7537783 A FR 7537783A FR 7537783 A FR7537783 A FR 7537783A FR 2293947 A1 FR2293947 A1 FR 2293947A1
Authority
FR
France
Prior art keywords
antimicrobial
coated
anionic
sutures
dressings
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7537783A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Priority to FR7537783A priority Critical patent/FR2293947A1/en
Publication of FR2293947A1 publication Critical patent/FR2293947A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0023—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using a quaternized group or a protonated amine group of the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Antimicrobial surgical articles, such as wound dressings, prosthetic devices, and esp. sutures, are coated with an elastomer of formula (I): (where R is 1-15C alkylene; R2 is lower alkylene; R3, R4 and R5 are each H or lower alkyl; R1 is a liq prepolymer rof mol. wt. 1000-3000, which is a polyether, silicone, polyurethane or polyamide; Z and Y are each OH or -NCO, ZY representing a urethane group; n = 10-1000; B circled negative = anionic polymer; X = an anionic or cationic antimicrobial compound). Any anionic or cationic antimicrobial agent may be used, and may be incorporated either when the article is manufactured or when it is used. Water, blood, etc. slowly leach the antimicrobial agent over a prolonged period.
FR7537783A 1975-12-10 1975-12-10 Antimicrobial sutures, dressings, prostheses - coated with an elastomeric polyurethane with pendant anionic or cationic antimicrobial cpds Withdrawn FR2293947A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7537783A FR2293947A1 (en) 1975-12-10 1975-12-10 Antimicrobial sutures, dressings, prostheses - coated with an elastomeric polyurethane with pendant anionic or cationic antimicrobial cpds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7537783A FR2293947A1 (en) 1975-12-10 1975-12-10 Antimicrobial sutures, dressings, prostheses - coated with an elastomeric polyurethane with pendant anionic or cationic antimicrobial cpds

Publications (1)

Publication Number Publication Date
FR2293947A1 true FR2293947A1 (en) 1976-07-09

Family

ID=9163571

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7537783A Withdrawn FR2293947A1 (en) 1975-12-10 1975-12-10 Antimicrobial sutures, dressings, prostheses - coated with an elastomeric polyurethane with pendant anionic or cationic antimicrobial cpds

Country Status (1)

Country Link
FR (1) FR2293947A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988000062A1 (en) * 1986-07-04 1988-01-14 Vsesojuzny Nauchno-Issledovatelsky I Ispytatelny I Ligature material
EP0537774A1 (en) * 1991-10-18 1993-04-21 Kuraray Co., Ltd. Antimicrobial polymerizable composition, the polymer and article obtained from the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988000062A1 (en) * 1986-07-04 1988-01-14 Vsesojuzny Nauchno-Issledovatelsky I Ispytatelny I Ligature material
EP0537774A1 (en) * 1991-10-18 1993-04-21 Kuraray Co., Ltd. Antimicrobial polymerizable composition, the polymer and article obtained from the same

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Legal Events

Date Code Title Description
ST Notification of lapse