FR2287227A1 - Apo- and desoxy-vincaminonitriles - for vascular insufficiency, prepd. by dehydration of the corresp. amides or aldoximes - Google Patents

Apo- and desoxy-vincaminonitriles - for vascular insufficiency, prepd. by dehydration of the corresp. amides or aldoximes

Info

Publication number
FR2287227A1
FR2287227A1 FR7434052A FR7434052A FR2287227A1 FR 2287227 A1 FR2287227 A1 FR 2287227A1 FR 7434052 A FR7434052 A FR 7434052A FR 7434052 A FR7434052 A FR 7434052A FR 2287227 A1 FR2287227 A1 FR 2287227A1
Authority
FR
France
Prior art keywords
vincaminonitriles
aldoximes
desoxy
corresp
prepd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7434052A
Other languages
French (fr)
Other versions
FR2287227B1 (en
Inventor
Don Pierre Rene Luc Giudicelli
Henry Najer
Patrick Andre Louis Lardenois
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7434052A priority Critical patent/FR2287227A1/en
Publication of FR2287227A1 publication Critical patent/FR2287227A1/en
Application granted granted Critical
Publication of FR2287227B1 publication Critical patent/FR2287227B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Novel nitriles of formula (I) (where R1 and R2 = H, or together form a bond) and their addn. salts are used for treatment of vascular insufficiency, esp. cerebral. Cpds. (I) are more active than vincamine and they have a better therapeutic index.
FR7434052A 1974-10-10 1974-10-10 Apo- and desoxy-vincaminonitriles - for vascular insufficiency, prepd. by dehydration of the corresp. amides or aldoximes Granted FR2287227A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7434052A FR2287227A1 (en) 1974-10-10 1974-10-10 Apo- and desoxy-vincaminonitriles - for vascular insufficiency, prepd. by dehydration of the corresp. amides or aldoximes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7434052A FR2287227A1 (en) 1974-10-10 1974-10-10 Apo- and desoxy-vincaminonitriles - for vascular insufficiency, prepd. by dehydration of the corresp. amides or aldoximes

Publications (2)

Publication Number Publication Date
FR2287227A1 true FR2287227A1 (en) 1976-05-07
FR2287227B1 FR2287227B1 (en) 1979-06-01

Family

ID=9143921

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7434052A Granted FR2287227A1 (en) 1974-10-10 1974-10-10 Apo- and desoxy-vincaminonitriles - for vascular insufficiency, prepd. by dehydration of the corresp. amides or aldoximes

Country Status (1)

Country Link
FR (1) FR2287227A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810709A (en) * 1984-07-11 1989-03-07 Richter Gedeon Vegyeszefi Gyar R.T. Nintrovincaminic acid derivatives having pharmaceutical utility

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7307338A (en) * 1972-05-26 1973-11-28

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7307338A (en) * 1972-05-26 1973-11-28

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810709A (en) * 1984-07-11 1989-03-07 Richter Gedeon Vegyeszefi Gyar R.T. Nintrovincaminic acid derivatives having pharmaceutical utility

Also Published As

Publication number Publication date
FR2287227B1 (en) 1979-06-01

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