FR2284328A1 - Orotate de thiamine disulfure et son procede de preparation - Google Patents
Orotate de thiamine disulfure et son procede de preparationInfo
- Publication number
- FR2284328A1 FR2284328A1 FR7527952A FR7527952A FR2284328A1 FR 2284328 A1 FR2284328 A1 FR 2284328A1 FR 7527952 A FR7527952 A FR 7527952A FR 7527952 A FR7527952 A FR 7527952A FR 2284328 A1 FR2284328 A1 FR 2284328A1
- Authority
- FR
- France
- Prior art keywords
- orotate
- preparation process
- disulphide
- thiamine
- thiamine disulphide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 title 1
- PXQPEWDEAKTCGB-UHFFFAOYSA-N orotic acid Chemical compound OC(=O)C1=CC(=O)NC(=O)N1 PXQPEWDEAKTCGB-UHFFFAOYSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 title 1
- 229960003495 thiamine Drugs 0.000 title 1
- 235000019157 thiamine Nutrition 0.000 title 1
- 239000011721 thiamine Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/557—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D415/00—Heterocyclic compounds containing the thiamine skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19742443979 DE2443979A1 (de) | 1974-09-12 | 1974-09-12 | Thiamindisulfid-orotat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2284328A1 true FR2284328A1 (fr) | 1976-04-09 |
| FR2284328B1 FR2284328B1 (en:Method) | 1979-09-14 |
Family
ID=5925726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7527952A Granted FR2284328A1 (fr) | 1974-09-12 | 1975-09-11 | Orotate de thiamine disulfure et son procede de preparation |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5161614A (en:Method) |
| AU (1) | AU8472375A (en:Method) |
| BE (1) | BE833351A (en:Method) |
| CH (1) | CH602666A5 (en:Method) |
| DE (1) | DE2443979A1 (en:Method) |
| FR (1) | FR2284328A1 (en:Method) |
| GB (1) | GB1477263A (en:Method) |
| NL (1) | NL7510703A (en:Method) |
| SE (1) | SE7510137L (en:Method) |
| ZA (1) | ZA755816B (en:Method) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8034823B2 (en) | 2005-02-22 | 2011-10-11 | Savvipharm Inc | Method of increasing drug oral bioavailability and compositions of less toxic orotate salts |
| DE102009025549A1 (de) * | 2009-06-15 | 2010-12-16 | Werth Akupunktur Center | Zusammensetzung für den Transport von Orotsäure über die Bluthirnschranke |
-
1974
- 1974-09-12 DE DE19742443979 patent/DE2443979A1/de active Pending
-
1975
- 1975-09-05 GB GB3662575A patent/GB1477263A/en not_active Expired
- 1975-09-11 JP JP50110836A patent/JPS5161614A/ja active Pending
- 1975-09-11 NL NL7510703A patent/NL7510703A/xx not_active Application Discontinuation
- 1975-09-11 AU AU84723/75A patent/AU8472375A/en not_active Expired
- 1975-09-11 FR FR7527952A patent/FR2284328A1/fr active Granted
- 1975-09-11 SE SE7510137A patent/SE7510137L/xx unknown
- 1975-09-11 ZA ZA00755816A patent/ZA755816B/xx unknown
- 1975-09-11 CH CH1177775A patent/CH602666A5/xx not_active IP Right Cessation
- 1975-09-12 BE BE159985A patent/BE833351A/xx unknown
Non-Patent Citations (1)
| Title |
|---|
| NEANT * |
Also Published As
| Publication number | Publication date |
|---|---|
| CH602666A5 (en:Method) | 1978-07-31 |
| AU8472375A (en) | 1977-03-17 |
| JPS5161614A (en) | 1976-05-28 |
| SE7510137L (sv) | 1976-03-15 |
| BE833351A (fr) | 1975-12-31 |
| GB1477263A (en) | 1977-06-22 |
| NL7510703A (nl) | 1976-03-16 |
| ZA755816B (en) | 1976-08-25 |
| DE2443979A1 (de) | 1976-04-29 |
| FR2284328B1 (en:Method) | 1979-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |