FR2279697A1 - Procede de dedoublement d'un melange racemique d'un compose oxo - Google Patents

Procede de dedoublement d'un melange racemique d'un compose oxo

Info

Publication number
FR2279697A1
FR2279697A1 FR7525891A FR7525891A FR2279697A1 FR 2279697 A1 FR2279697 A1 FR 2279697A1 FR 7525891 A FR7525891 A FR 7525891A FR 7525891 A FR7525891 A FR 7525891A FR 2279697 A1 FR2279697 A1 FR 2279697A1
Authority
FR
France
Prior art keywords
dedoubement
racemic mixture
oxo compound
oxo
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7525891A
Other languages
English (en)
Other versions
FR2279697B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2279697A1 publication Critical patent/FR2279697A1/fr
Application granted granted Critical
Publication of FR2279697B1 publication Critical patent/FR2279697B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7525891A 1972-07-24 1975-08-21 Procede de dedoublement d'un melange racemique d'un compose oxo Granted FR2279697A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/274,650 US4130721A (en) 1972-07-24 1972-07-24 11-Deoxy PGE2 compounds

Publications (2)

Publication Number Publication Date
FR2279697A1 true FR2279697A1 (fr) 1976-02-20
FR2279697B1 FR2279697B1 (fr) 1979-05-18

Family

ID=23049085

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7326877A Expired FR2193609B1 (fr) 1972-07-24 1973-07-23
FR7525891A Granted FR2279697A1 (fr) 1972-07-24 1975-08-21 Procede de dedoublement d'un melange racemique d'un compose oxo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7326877A Expired FR2193609B1 (fr) 1972-07-24 1973-07-23

Country Status (10)

Country Link
US (1) US4130721A (fr)
AU (1) AU471942B2 (fr)
BE (1) BE802737A (fr)
CA (1) CA997338A (fr)
CH (1) CH586674A5 (fr)
DE (1) DE2332400A1 (fr)
FR (2) FR2193609B1 (fr)
GB (1) GB1434620A (fr)
MX (1) MX3367E (fr)
NL (1) NL7309856A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045577A (en) * 1971-06-17 1977-08-30 Alza Corporation Valuable medicinial prostaglandin compounds prepared from material isolated from the sea
DE2702367A1 (de) * 1977-01-21 1978-08-03 Hoechst Ag Neue prostaglandin-analoge und verfahren zu ihrer herstellung
US5049497A (en) * 1986-08-25 1991-09-17 Syntex (U.S.A.) Inc. Novel process for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives
US5468778A (en) * 1992-09-24 1995-11-21 Allergan, Inc. Method of lowering intraocular pressure by administering a pharmaceutical composition containing 7-(5-substituted cyclopentyl) and 7-(5-substituted-cyclopentenyl) 5-heptenoic acids and derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3069322A (en) * 1958-05-28 1962-12-18 Bergstrom Sune Pge and pgf
FR2085654B1 (fr) * 1970-04-30 1973-06-08 Roussel Uclaf
FR2085652B1 (fr) * 1970-04-30 1973-08-10 Roussel Uclaf
JPS503362B1 (fr) * 1970-06-10 1975-02-04
DE2231244A1 (de) * 1971-06-28 1973-01-11 Ayerst Mckenna & Harrison Verfahren zur herstellung von derivaten der prostansaeure, ihrer homologen und ihrer zwischenprodukte

Also Published As

Publication number Publication date
FR2193609B1 (fr) 1976-12-24
FR2193609A1 (fr) 1974-02-22
FR2279697B1 (fr) 1979-05-18
NL7309856A (fr) 1974-01-28
BE802737A (fr) 1974-01-24
CH586674A5 (fr) 1977-04-15
DE2332400A1 (de) 1974-02-14
US4130721A (en) 1978-12-19
GB1434620A (en) 1976-05-05
AU471942B2 (en) 1976-05-06
AU5727773A (en) 1975-01-09
MX3367E (es) 1980-10-15
CA997338A (en) 1976-09-21

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Legal Events

Date Code Title Description
ST Notification of lapse