FR2277575A1 - Nouveaux derives de la dihydroxy-3,4 phenylalanine, leurs sels, leur preparation et les medicaments qui en contiennent - Google Patents
Nouveaux derives de la dihydroxy-3,4 phenylalanine, leurs sels, leur preparation et les medicaments qui en contiennentInfo
- Publication number
- FR2277575A1 FR2277575A1 FR7423908A FR7423908A FR2277575A1 FR 2277575 A1 FR2277575 A1 FR 2277575A1 FR 7423908 A FR7423908 A FR 7423908A FR 7423908 A FR7423908 A FR 7423908A FR 2277575 A1 FR2277575 A1 FR 2277575A1
- Authority
- FR
- France
- Prior art keywords
- phenyl
- derivs
- opt
- biological membranes
- lipophilic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012528 membrane Substances 0.000 title abstract 3
- 208000027089 Parkinsonian disease Diseases 0.000 title abstract 2
- 206010034010 Parkinsonism Diseases 0.000 title abstract 2
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 title 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 title 1
- 230000035515 penetration Effects 0.000 title 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/36—One oxygen atom
- C07D263/38—One oxygen atom attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7423908A FR2277575A1 (fr) | 1974-07-10 | 1974-07-10 | Nouveaux derives de la dihydroxy-3,4 phenylalanine, leurs sels, leur preparation et les medicaments qui en contiennent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7423908A FR2277575A1 (fr) | 1974-07-10 | 1974-07-10 | Nouveaux derives de la dihydroxy-3,4 phenylalanine, leurs sels, leur preparation et les medicaments qui en contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2277575A1 true FR2277575A1 (fr) | 1976-02-06 |
| FR2277575B1 FR2277575B1 (enExample) | 1978-07-21 |
Family
ID=9141090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7423908A Granted FR2277575A1 (fr) | 1974-07-10 | 1974-07-10 | Nouveaux derives de la dihydroxy-3,4 phenylalanine, leurs sels, leur preparation et les medicaments qui en contiennent |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2277575A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1985002609A1 (en) * | 1983-12-08 | 1985-06-20 | Alkaloida Vegyészeti Gyár | Preparation of phenyl alanines by hydrogenation of phenyl serines |
| JP5423905B2 (ja) * | 2010-12-02 | 2014-02-19 | 小野薬品工業株式会社 | 新規化合物及びその医薬用途 |
-
1974
- 1974-07-10 FR FR7423908A patent/FR2277575A1/fr active Granted
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1985002609A1 (en) * | 1983-12-08 | 1985-06-20 | Alkaloida Vegyészeti Gyár | Preparation of phenyl alanines by hydrogenation of phenyl serines |
| AU570090B2 (en) * | 1983-12-08 | 1988-03-03 | Vegyeszeti Gyar Alkaloida | Preparation of 3-phenyl alanines derivatives |
| JP5423905B2 (ja) * | 2010-12-02 | 2014-02-19 | 小野薬品工業株式会社 | 新規化合物及びその医薬用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2277575B1 (enExample) | 1978-07-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |