FR2276814A1 - Nouveaux derives de la thiocolchicine, procede de fabrication de ceux-ci et medicaments en derivant - Google Patents
Nouveaux derives de la thiocolchicine, procede de fabrication de ceux-ci et medicaments en derivantInfo
- Publication number
- FR2276814A1 FR2276814A1 FR7520936A FR7520936A FR2276814A1 FR 2276814 A1 FR2276814 A1 FR 2276814A1 FR 7520936 A FR7520936 A FR 7520936A FR 7520936 A FR7520936 A FR 7520936A FR 2276814 A1 FR2276814 A1 FR 2276814A1
- Authority
- FR
- France
- Prior art keywords
- derivatives
- thiocolchicine
- medicines
- manufacturing
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- CMEGANPVAXDBPL-INIZCTEOSA-N n-[(7s)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5h-benzo[a]heptalen-7-yl]acetamide Chemical class C1([C@@H](NC(C)=O)CC2)=CC(=O)C(SC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC CMEGANPVAXDBPL-INIZCTEOSA-N 0.000 title 2
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/23—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB29746/74A GB1513724A (en) | 1974-07-04 | 1974-07-04 | Derivatives of thiocolchicine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2276814A1 true FR2276814A1 (fr) | 1976-01-30 |
| FR2276814B1 FR2276814B1 (show.php) | 1978-07-28 |
Family
ID=10296505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7520936A Granted FR2276814A1 (fr) | 1974-07-04 | 1975-07-03 | Nouveaux derives de la thiocolchicine, procede de fabrication de ceux-ci et medicaments en derivant |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US3997506A (show.php) |
| FR (1) | FR2276814A1 (show.php) |
| GB (1) | GB1513724A (show.php) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4692463A (en) * | 1985-02-26 | 1987-09-08 | The United States Of America As Represented By The Department Of Health And Human Services | Antiinflammatory 2,3-didemethylcolchicine and additional derivatives |
| US5175342A (en) * | 1988-08-24 | 1992-12-29 | The United States Of America As Represented By The Department Of Health And Human Services | Esters of 3-demethylthiocolchicine and n-acyl analogs |
| US20050095197A1 (en) * | 2003-10-31 | 2005-05-05 | Tuszynski Jack A. | Anti-mitotic compound |
| US20060148674A1 (en) * | 2004-12-31 | 2006-07-06 | Luduena Richard F | Therapeutic composition |
| CA3136489A1 (en) * | 2018-06-29 | 2020-01-02 | Alberta Health Services | Methods and uses of colchicine derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3657273A (en) * | 1970-05-01 | 1972-04-18 | Searle & Co | Adamantane-1 3-dicarboxamides |
-
1974
- 1974-07-04 GB GB29746/74A patent/GB1513724A/en not_active Expired
-
1975
- 1975-07-03 FR FR7520936A patent/FR2276814A1/fr active Granted
- 1975-07-07 US US05/593,863 patent/US3997506A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2276814B1 (show.php) | 1978-07-28 |
| US3997506A (en) | 1976-12-14 |
| GB1513724A (en) | 1978-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |