FR2276044A1 - Substd. 1-amino-isoindolenines - as local anaesthetics antiarrhythmic agents - Google Patents
Substd. 1-amino-isoindolenines - as local anaesthetics antiarrhythmic agentsInfo
- Publication number
- FR2276044A1 FR2276044A1 FR7519707A FR7519707A FR2276044A1 FR 2276044 A1 FR2276044 A1 FR 2276044A1 FR 7519707 A FR7519707 A FR 7519707A FR 7519707 A FR7519707 A FR 7519707A FR 2276044 A1 FR2276044 A1 FR 2276044A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- substd
- alkoxy
- amino
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
Abstract
1-Amino isoindoles, (I), their acid addition and quaternary salts, (where R is halogen, dialkylamino 1-4C alkoxy or methylene- or ethylene-dioxy; R1 is H, 1-4C alkyl or alkoxy, OH, 7-10C -phenylalkyl, Ph2CH or phenyl opt. substd. by halogen, OH, 1-4C -alkyl or -alkoxy; R2 is H or 1-4C alkyl; R3 is H, 1-4C alkyl or A-NR5R6, A is 1-4C alkylene; R5 and R6 are H or 1-4C alkyl or NR5R6 is a satd. 5 or 6-membered heterocyclic ring opt. contg. another O or N atom and opt. substd. by 1-4C alkyl, phenyl, benzyl or benzoylamine, R4 is an aromatic carbocyclic or heterocyclic ring system of one or two rings and in which a bicyclic ring system may contain a saturated or partly saturated rings and the aromatic ring may be substd. by 1-4C alkyl, halogen, 1-6C alkoxy, cycloalkoxy, CF3, 1-4C alkanoyl or alkanoylamino, 1-4C dialkylamino, CN, methyleneor ethylene-dioxy) are local anaesthetics and antiarrhythmic agents.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19742430354 DE2430354A1 (en) | 1974-06-25 | 1974-06-25 | NEW SUBSTITUTED 1-AMINO-ISOINDOLES, PROCESS FOR THEIR MANUFACTURING AND THESE PHARMACEUTICAL PREPARATIONS |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2276044A1 true FR2276044A1 (en) | 1976-01-23 |
Family
ID=5918862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7519707A Withdrawn FR2276044A1 (en) | 1974-06-25 | 1975-06-24 | Substd. 1-amino-isoindolenines - as local anaesthetics antiarrhythmic agents |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS51125071A (en) |
BE (1) | BE830506A (en) |
DE (1) | DE2430354A1 (en) |
DK (1) | DK285375A (en) |
FR (1) | FR2276044A1 (en) |
NL (1) | NL7507569A (en) |
SE (1) | SE7507178L (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007030582A2 (en) * | 2005-09-09 | 2007-03-15 | Bristol-Myers Squibb Company | Acyclic ikur inhibitors |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0208985A (en) * | 2001-04-19 | 2004-03-09 | Eisai Co Ltd | 2-iminopyrrolidine derivatives |
AU2004218187C1 (en) | 2003-02-19 | 2011-04-07 | Eisai R&D Management Co., Ltd. | Methods for producing cyclic benzamidine derivatives |
ES2436795T3 (en) | 2005-06-14 | 2014-01-07 | Merck Sharp & Dohme Corp. | Aspartyl protease heterocyclic inhibitors, preparation and use thereof |
-
1974
- 1974-06-25 DE DE19742430354 patent/DE2430354A1/en active Pending
-
1975
- 1975-06-20 BE BE157568A patent/BE830506A/en unknown
- 1975-06-23 SE SE7507178A patent/SE7507178L/en not_active Application Discontinuation
- 1975-06-24 FR FR7519707A patent/FR2276044A1/en not_active Withdrawn
- 1975-06-24 DK DK285375A patent/DK285375A/en unknown
- 1975-06-24 JP JP7702475A patent/JPS51125071A/en active Pending
- 1975-06-25 NL NL7507569A patent/NL7507569A/en unknown
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007030582A2 (en) * | 2005-09-09 | 2007-03-15 | Bristol-Myers Squibb Company | Acyclic ikur inhibitors |
WO2007030582A3 (en) * | 2005-09-09 | 2007-06-14 | Bristol Myers Squibb Co | Acyclic ikur inhibitors |
US7915410B2 (en) | 2005-09-09 | 2011-03-29 | Bristol-Myers Squibb Company | Acyclic IKur inhibitors |
US8357809B2 (en) | 2005-09-09 | 2013-01-22 | Bristol-Myers Squibb Company | Acyclic IKur inhibitors |
Also Published As
Publication number | Publication date |
---|---|
SE7507178L (en) | 1975-12-29 |
NL7507569A (en) | 1975-12-30 |
JPS51125071A (en) | 1976-11-01 |
DE2430354A1 (en) | 1976-01-15 |
BE830506A (en) | 1975-12-22 |
DK285375A (en) | 1975-12-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Withdrawal of published application |