FR2263769A1 - 2-Substd-tetrahydrodicycloalk (e,g) isoindolins - useful against rhino-and corona virus infections - Google Patents

2-Substd-tetrahydrodicycloalk (e,g) isoindolins - useful against rhino-and corona virus infections

Info

Publication number
FR2263769A1
FR2263769A1 FR7325569A FR7325569A FR2263769A1 FR 2263769 A1 FR2263769 A1 FR 2263769A1 FR 7325569 A FR7325569 A FR 7325569A FR 7325569 A FR7325569 A FR 7325569A FR 2263769 A1 FR2263769 A1 FR 2263769A1
Authority
FR
France
Prior art keywords
corona virus
tetrahydrodicycloalk
isoindolins
substd
virus infections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7325569A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of FR2263769A1 publication Critical patent/FR2263769A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Title cpds. of formula (I) (where m = 0-3) and their acceptable acid addn. salts are prepd. by reducing a cpd. (II) (where X is methylene or carbonyl). Redn is in inert solvent using mixed metal hydrides such as sodium bis(2-methoxyethoxy)aluminium-hydride or LiAlH4 etc. (I) have antiviral activity against rhino- and corona virus and may be used for the prevention, stabilisation or treatment of inflections caused by these viri in the upper respiratory tract. (I) do not show much irritation of the eye and nose tissue upon transnasal administration. They have low toxicity and show few side-effects.
FR7325569A 1972-07-13 1973-07-12 2-Substd-tetrahydrodicycloalk (e,g) isoindolins - useful against rhino-and corona virus infections Withdrawn FR2263769A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27159472A 1972-07-13 1972-07-13

Publications (1)

Publication Number Publication Date
FR2263769A1 true FR2263769A1 (en) 1975-10-10

Family

ID=23036246

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7325569A Withdrawn FR2263769A1 (en) 1972-07-13 1973-07-12 2-Substd-tetrahydrodicycloalk (e,g) isoindolins - useful against rhino-and corona virus infections

Country Status (8)

Country Link
JP (1) JPS4951265A (en)
BE (1) BE802239A (en)
DE (1) DE2334984A1 (en)
FR (1) FR2263769A1 (en)
IL (1) IL42729A0 (en)
LU (1) LU68017A1 (en)
NL (1) NL7309824A (en)
ZA (1) ZA734758B (en)

Also Published As

Publication number Publication date
NL7309824A (en) 1974-01-15
IL42729A0 (en) 1973-10-25
BE802239A (en) 1974-01-14
ZA734758B (en) 1974-06-26
LU68017A1 (en) 1973-09-14
JPS4951265A (en) 1974-05-18
DE2334984A1 (en) 1974-01-31

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Legal Events

Date Code Title Description
ST Notification of lapse